Allogeneic Adipose-Derived Stem Cells Protect Fat Grafts at the Early Stage and Improve Long-Term Retention in Immunocompetent Rats

2015 ◽  
Vol 39 (4) ◽  
pp. 625-634 ◽  
Author(s):  
Jun Zhang ◽  
Yunchuan Wang ◽  
Bin Zhao ◽  
Lei Fan ◽  
Xiaozhi Bai ◽  
...  
Keyword(s):  
Stem Cells ◽  
Early Stage ◽  
Adipose Derived Stem Cells ◽  
Fat Grafts ◽  
Term Retention ◽  
Long Term Retention

scholarly journals Early stage visual-orthographic processes predict long-term retention of word form and meaning: A visual encoding training study

2013 ◽  
Vol 26 (4) ◽  
pp. 440-461 ◽  
Author(s):  
Fan Cao ◽  
Ben Rickles ◽  
Marianne Vu ◽  
Ziheng Zhu ◽  
Derek Ho Lung Chan ◽  
...  
Keyword(s):  
Early Stage ◽  
Word Form ◽  
Training Study ◽  
Term Retention ◽  
Visual Encoding ◽  
Long Term Retention

Utilizing Muscle-Derived Stem Cells to Enhance Long-Term Retention and Aesthetic Outcome of Autologous Fat Grafting: Pilot Study in Mice

2011 ◽  
Vol 36 (1) ◽  
pp. 186-192 ◽  
Author(s):  
Zhiqiang Ma ◽  
Duanyang Han ◽  
Peipei Zhang ◽  
Jenny F. Yang ◽  
Yiqiang Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Pilot Study ◽  
Fat Grafting ◽  
Aesthetic Outcome ◽  
Autologous Fat Grafting ◽  
Autologous Fat ◽  
Term Retention ◽  
Long Term Retention

scholarly journals ROLE OF FLIPPED CLASSROOM METHOD IN SHORT AND LONG TERM RETENTION IN ANATOMY

2020 ◽  
Author(s):  
Payal Kasat ◽  
Vishwajit Deshmukh ◽  
Gayatri Muthiyan ◽  
Gugapriya T.S. ◽  
Aaditya Tarnekar ◽  
...  
Keyword(s):  
Medical Education ◽  
Flipped Classroom ◽  
Early Stage ◽  
Student Centered ◽  
Assessment Scores ◽  
Term Retention ◽  
Short And Long Term ◽  
Long Term Retention ◽  
Teaching Learning

Introduction: Medical education is changing towards more flexible, effective, active and student-centered teaching strategies that reduces the limitations of traditional methods of education. Recently, the flipped classroom method has been suggested to support this transition. However, research on the use of flipped classroom method in medical education is at its early stage and little is known about its effect on students learning in relation to short and long-term retention of the topics. Aims: The present paper aims to study the comparative effect of traditional and flipped classroom method on short-term and long-term memories of first MBBS students in Anatomy with the aid of technology to promote learning. Materials and methods: 50 first year MBBS students were subjected to traditional and flipped classroom module separately. Immediate assessments were done at the completion of the module. Followed by a gap of 2 months, the students were again assessed on the content taught in the module as a part of formative assessment. The data so obtained was compared and analyzed statistically. Result: The assessment scores showed differences between the two methods of teaching in short as well as long term. The flipped classroom method was observed to have significant long-term retention which was evident by assessment scores. Conclusion: The study concludes that flipped classroom method serves as an advantageous tool and motivating factor for effective learning, understanding and retention of conceptual and factual anatomical content. Keywords: Traditional classroom, flipped classroom, teaching learning method

Quantifying Long-Term Retention of Excised Fat Grafts

2017 ◽  
Vol 139 (5) ◽  
pp. 1223-1232 ◽  
Author(s):  
Mikkel Herly ◽  
Mathias Ørholt ◽  
Peter V. Glovinski ◽  
Christian B. Pipper ◽  
Helle Broholm ◽  
...  
Keyword(s):  
Fat Grafts ◽  
Term Retention ◽  
Long Term Retention

scholarly journals Human adipose-derived stem cells enriched with VEGF-modified mRNA promote angiogenesis and long-term graft survival in a fat graft transplantation model

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Fei Yu ◽  
Nevin Witman ◽  
Dan Yan ◽  
Siyi Zhang ◽  
Meng Zhou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Graft Survival ◽  
Fat Graft ◽  
Adipose Derived Stem Cells ◽  
Fat Grafts ◽  
Apoptosis And Necrosis ◽  
Transplantation Model

Abstract Background Fat grafting, as a standard treatment for numerous soft tissue defects, remains unpredictable and technique-dependent. Human adipose-derived stem cells (hADSCs) are promising candidates for cell-assisted therapy to improve graft survival. As free-living fat requires nutritional and respiratory sources to thrive, insufficient and unstable vascularization still impedes hADSC-assisted therapy. Recently, cytotherapy combined with modified mRNA (modRNA) encoding vascular endothelial growth factor (VEGF) has been applied for the treatment of ischemia-related diseases. Herein, we hypothesized that VEGF modRNA (modVEGF)-engineered hADSCs could robustly enhance fat survival in a fat graft transplantation model. Methods hADSCs were acquired from lipoaspiration and transfected with modRNAs. Transfection efficiency and expression kinetics of modRNAs in hADSCs were first evaluated in vitro. Next, we applied an in vivo Matrigel plug assay to assess the viability and angiogenic potential of modVEGF-engineered hADSCs at 1 week post-implantation. Finally, modVEGF-engineered hADSCs were co-transplanted with human fat in a murine model to analyze the survival rate, re-vascularization, proliferation, fibrosis, apoptosis, and necrosis of fat grafts over long-term follow-up. Results Transfections of modVEGF in hADSCs were highly tolerable as the modVEGF-engineered hADSCs facilitated burst-like protein production of VEGF in both our in vitro and in vivo models. modVEGF-engineered hADSCs induced increased levels of cellular proliferation and proangiogenesis when compared to untreated hADSCs in both ex vivo and in vivo assays. In a fat graft transplantation model, we provided evidence that modVEGF-engineered hADSCs promote the optimal potency to preserve adipocytes, especially in the long-term post-transplantation phase. Detailed histological analysis of fat grafts harvested at 15, 30, and 90 days following in vivo grafting suggested the release of VEGF protein from modVEGF-engineered hADSCs significantly improved neo-angiogenesis, vascular maturity, and cell proliferation. The modVEGF-engineered hADSCs also significantly mitigated the presence of fibrosis, apoptosis, and necrosis of grafts when compared to the control groups. Moreover, modVEGF-engineered hADSCs promoted graft survival and cell differentiation abilities, which also induced an increase in vessel formation and the number of surviving adipocytes after transplantation. Conclusion This current study demonstrates the employment of modVEGF-engineered hADSCs as an advanced alternative to the clinical treatment involving soft-tissue reconstruction and rejuvenation.

Long-term retention is greater following closed-book tests than open-book tests

2006 ◽  
Author(s):  
Pooja K. Agarwal ◽  
Jeffrey D. Karpicke ◽  
Sean H. Kang ◽  
Henry L. Roediger ◽  
Kathleen B. McDermott
Keyword(s):  
Open Book ◽  
Term Retention ◽  
Long Term Retention

Retrieval practice promotes long-term retention irrespective of the placement

2020 ◽  
Author(s):  
alice latimier ◽  
Arnaud Rierget ◽  
Son Thierry Ly ◽  
Franck Ramus
Keyword(s):  
Retention Interval ◽  
Retrieval Practice ◽  
Memory Retention ◽  
Term Retention ◽  
Long Term Retention

The current study aimed at comparing the effect of three placements of the re-exposure episodes on memory retention (interpolated-small, interpolated-medium, postponed), depending on whether retrieval practice or re-reading was used, and on retention interval (one week vs one month).

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