Total Thyroidectomy for Benign Thyroid Disorders in an Endemic Region

2001 ◽  
Vol 25 (3) ◽  
pp. 307-310 ◽  
Author(s):  
Anjali Mishra ◽  
Amit Agarwal ◽  
Gaurav Agarwal ◽  
S.K. Mishra
2010 ◽  
Vol 34 (3) ◽  
pp. 527-531 ◽  
Author(s):  
Ranjith Sukumar ◽  
Amit Agarwal ◽  
Sushil Gupta ◽  
Anjali Mishra ◽  
Gaurav Agarwal ◽  
...  

2019 ◽  
Vol 6 (7) ◽  
pp. 2267
Author(s):  
Ahmed Mohamed Gamal ◽  
Nagm Eldin Abu Elnaga ◽  
Mahmoud Thabet Ayoub ◽  
Abdel Radi Abdel Salam Farghally

Background: Although total thyroidectomy has become the operation of choice in treatment of BMNG, it leads to permanent hypothyroidism which lead the patient to take a lifelong exogenous hormone replacement therapy, which involves daily administration of levothyroxine at a dose that must be in close follow-up in terms of thyroid hormone levels. In addition, reaching euthyroid status using hormone replacement therapy can be affected in  presence of other medical problems that interfere with absorption of the drug as mal-absorption syndrome. When all these are considered, there is a necessity of a novel method to avoid the occurrence of postoperative hypothyroidism.Methods: A case series prospective study carried out over 30 patients with benign thyroid disorders for whom total thyroidectomy is indicated to evaluate the capacity of auto-implanted thyroid tissue in achieving an euthyroid state without any need for life-long hormone replacement therapy. Postoperative Assessment consists of repeated thyroid function tests and thyroid scan with complementary SPECT/CT.Results: significant gradual increase in serum levels of T3 and T4 with corresponding decrease in TSH levels returning to normal levels 6-9 months postoperatively. Thyroid scan with complementary SPECT/CT was done for 15 patients to evaluate the functional capacity of the thyroid implant.  Among the 15 patients, 13 patients have functioning thyroid implant (success percent: 6.6%). whereas 2 patients show non functioning thyroid implant (failure percent: 13.3%).Conclusions: Thyroid Auto-transplantation following total thyroidectomy in benign thyroid disorders is an effective method to prevent postoperative hypothyroidism.


2015 ◽  
Vol 87 (4) ◽  
pp. 309-316
Author(s):  
Sophocles Lanitis ◽  
V. Ganis ◽  
G. Sgourakis ◽  
P. Brotzakis ◽  
A. Bryonidou ◽  
...  

1999 ◽  
Vol 26 (11) ◽  
pp. 1453-1457 ◽  
Author(s):  
E. K. J. Pauwels ◽  
W. H. Thomson ◽  
J. A. K. Blokland ◽  
M. E. Schmidt ◽  
M. Bourguignon ◽  
...  

2014 ◽  
Vol 75 (4) ◽  
pp. 241-246 ◽  
Author(s):  
Delphine Bernard ◽  
Marie Dominique Desruet ◽  
Marianne Wolf ◽  
Julie Roux ◽  
Camille Boin ◽  
...  

2014 ◽  
Vol 272 (9) ◽  
pp. 2457-2461 ◽  
Author(s):  
Peter Ambe ◽  
Katharina Lindecke ◽  
W. T. Knoefel ◽  
Alexander Rehders

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Adel Alawady ◽  
Alaal Khalil ◽  
salah abdelaal ◽  
Mohamed Alkilany ◽  
Hassan Ashour

Author(s):  
Nicolas Aide ◽  
Elif Hindié ◽  
Stéphane Bardet ◽  
David Taïeb

2007 ◽  
Vol 12 (4) ◽  
pp. 202-204
Author(s):  
Rajiv Singh ◽  
Mark Aitken

Background: Improvements in health service provision need not be costly and indeed may save money. Administration of radio iodine (131I) to patients with thyrotoxicosis in the UK is often delayed because few endocrinologists have appropriate Administration of Radioactive Substances Advisory Committee (ARSAC) certification. Hence referral must be made to an oncologist. We tried to reduce the time to treatment by acquiring an appropriate licence for an endocrinologist and hence eliminating need for further referral. Methods: An observational study of 414 doses of 131I administered to 353 patients for benign thyroid disorders at a district general hospital by either endocrinologist or oncologist. After decision to treat had been made, the time taken for treatment to be given was compared between the groups. Results: An endocrinologist licensed to prescribe 131I reduced the time taken from referral to administration of 131I from 28 to 12 days ( P < 0.001) compared with oncologists. A further group seen by another endocrinologist and then referred to the licensed endocrinologist also had their delay reduced to 19 days. Treatment was administered within three weeks in 88% of treatments by the endocrinologist, 62% by the non-licensed endocrinologist and only 28% by oncologists. Conclusions: Improving treatment times for patients were achieved at no extra cost and indeed freed up time for oncologists. Encouraging alternative means of delivering services can result in not only better services but also in cost savings. As certification is simple, endocrinologists should be encouraged to deliver 131I themselves rather than devolving care to other practitioners.


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