Visual Analogue Score for Urinary Symptoms—VASUS, validation of a visual scale for lower urinary tract symptoms (LUTS) in an African country

Objective: Double-J stent is a common tool used in urological procedures that is inserted for 2–6 weeks, but it may induce abdominal and flank pain, incontinence and irritative urinary symptoms. Alleviation of such symptoms would be useful to improve the patients’ quality of life. Accordingly, in this study, the efficacy of cystone versus tamsulosin in the treatment of double-J stent-related lower urinary tract symptoms was determined. Materials and methods: In this randomised clinical trial, 128 patients who required double-J stent insertion after transureteral lithotripsy during 2018–2019 were enrolled. They were randomly assigned to receive either cystone, tamsulosin, both, or placebo. The international prostate symptom score and visual analogue score data were recorded at baseline, after 2 and 4 weeks across the groups. Results: The international prostate symptom score and visual analogue score factors were statistically different across the case groups receiving cystone, tamsulosin and both drugs versus placebo ( P=0.001). Two weeks after drug administration, the visual analogue score and international prostate symptom score were not statistically different in the tamsulosin, cystone and dual therapy groups; however, after 4 weeks the cystone group had the lowest symptoms. Conclusion: Both tamsulosin and cystone are efficient drugs which would relieve stent-related lower urinary tract symptoms. The administration of cystone with or without tamsulosin for 4 weeks may have the best result in reducing the visual analogue score and international prostate symptom score. Level of evidence: Level I, 1b, therapeutic study, randomised controlled trial

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STUDY OF PREVALENCE OF LOWER URINARY TRACT SYMPTOMS IN PATIENTS UNDERGOING INGUINAL HERNIA REPAIR AT SKMCH, MUZAFFARPUR, BIHAR

10.36106/ijsr/6736143 ◽

2021 ◽

pp. 51-53

Author(s):

Sanjay Kumar ◽

Kumar Vikram ◽

Manoj Kumar ◽

Debarshi Jana

Keyword(s):

Inguinal Hernia ◽

Urinary Tract ◽

Hernia Repair ◽

Inguinal Hernia Repair ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Urinary Symptoms ◽

Number Of Patients ◽

Urinary Tract Symptoms ◽

Lower Urinary

Background: Lower urinary tract symptoms (LUTS) are frequently associated with inguinal hernias. It is important to recognise and treat bladder outlet obstruction in patients before inguinal hernia repair to prevent recurrence of hernia. Methods: This prospective study was conducted at Department of Surgery, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar. Hundred patients who presented with inguinal hernia repair were evaluated for LUTS using AUA scoring for urinary symptoms, uroowmetry (Qmax) and post voidal residual urine using ultrasonography along with urine routine microscopic examination and urine culture and sensitivity. Results: Eleven patients out of 100 who came for hernia repair had clinically signicant LUTS due to benign enlargement of prostate (BEP) and required treatment for BEP but none of these 11 patients had urinary symptoms as primary complaint. Ten patients were found to have urinary tract infection without any urinary symptom. Three patients had urethral stricture out of which 2 had Qmax of <10 ml/second. Conclusions: Signicant number of patients (14 percent) with inguinal hernia had lower urinary tract symptoms. An effort should be made to identify LUTS in patients presenting with inguinal hernia before surgery and treat the cause of LUTS. Ten percent of patients had asymptomatic UTI with AUA score less than 8 but Qmax on uroowmetry was in between 10-15 ml/second.

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Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions

Journal of Aging Research ◽

10.1155/2018/1582092 ◽

2018 ◽

Vol 2018 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Chi-Hang Yee ◽

Ching Leung ◽

Yuki Yu-Ting Wong ◽

Sylvia Lee ◽

Jenny Li ◽

...

Keyword(s):

Urinary Tract ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

White Matter Lesions ◽

Community Dwelling ◽

Urinary Symptoms ◽

Cerebral White Matter ◽

Mri Brain ◽

Urinary Tract Symptoms ◽

Lower Urinary

Aim. We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function.Methods. A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment. WMLs were graded using the Fazekas scale from 0 to 3. A separate telephone interview was carried out to assess the urinary symptoms in these subjects using the questionnaire Overactive Bladder-Validated 8-Question Awareness Tool (OAB-V8).Results. 800 community-dwelling elderly subjects were recruited to undergo MRI brain. In this cohort, 431 subjects responded to the telephone interview concerning their urinary symptoms. Among the respondents, 21.1% did not exhibit any WML on their MRI brain. Most of the subjects (52.6%) exhibited grade 1 WML. On logistic regression, age was found to be positively correlated with the Fazekas score (correlation coefficient 0.203,p≤0.01). Using a cutoff of 8 on OAB-V8, 22% of the respondents experienced OAB. Presence of WML, hypertension, or diabetes mellitus was not found to be correlated with storage urinary symptoms or OAB-V8 total score. Multiple logistic regression analysis did not show the presence of WML to be associated with the diagnosis of OAB (adjusted OR 1.13, 95% CI 0.65–1.96,p=0.659).Conclusions. WML is associated with age and is common in the elderly population. Mild WML is subclinical, with no obvious neurological and urinary symptoms. Our cohort did not demonstrate a relationship between WML and lower urinary tract symptoms.

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The Comprehensive Assessment of Self-Reported Urinary Symptoms: A New Tool for Research on Subtypes of Patients with Lower Urinary Tract Symptoms

The Journal of Urology ◽

10.1097/ju.0000000000000140 ◽

2019 ◽

Vol 201 (6) ◽

pp. 1177-1183 ◽

Cited By ~ 5

Author(s):

Kevin P. Weinfurt ◽

James W. Griffith ◽

Kathryn E. Flynn ◽

David Cella ◽

Tamara Bavendam ◽

...

Keyword(s):

Urinary Tract ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Comprehensive Assessment ◽

Urinary Symptoms ◽

Urinary Tract Symptoms ◽

Lower Urinary

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Seasonal Variation of Urinary Symptoms in Korean Men with Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

The World Journal of Men s Health ◽

10.5534/wjmh.2015.33.2.81 ◽

2015 ◽

Vol 33 (2) ◽

pp. 81 ◽

Cited By ~ 5

Author(s):

Ho Chul Choi ◽

Jong Kyu Kwon ◽

Joo Yong Lee ◽

Jang Hee Han ◽

Hae Do Jung ◽

...

Keyword(s):

Seasonal Variation ◽

Urinary Tract ◽

Benign Prostatic Hyperplasia ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Prostatic Hyperplasia ◽

Urinary Symptoms ◽

Urinary Tract Symptoms ◽

Lower Urinary

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Prevalence of lower urinary tract symptoms in patients undergoing inguinal hernia repair

International Surgery Journal ◽

10.18203/2349-2902.isj20194177 ◽

2019 ◽

Vol 6 (10) ◽

pp. 3576

Author(s):

Sudhir Kumar Jain ◽

Tariq Hameed ◽

Shankar Sundarraj ◽

Faiz Manzar Ansari

Keyword(s):

Inguinal Hernia ◽

Urinary Tract ◽

Hernia Repair ◽

Inguinal Hernia Repair ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Urinary Symptoms ◽

Number Of Patients ◽

Urinary Tract Symptoms ◽

Lower Urinary

Background: Lower urinary tract symptoms (LUTS) are frequently associated with inguinal hernias. It is important to recognise and treat bladder outlet obstruction in patients before inguinal hernia repair to prevent recurrence of hernia.Methods: This prospective study was conducted at Maulana Azad Medical College. Hundred patients who presented with inguinal hernia repair were evaluated for LUTS using AUA scoring for urinary symptoms, uroflowmetry (Qmax) and post voidal residual urine using ultrasonography along with urine routine microscopic examination and urine culture and sensitivity.Results: Eleven patients out of 100 who came for hernia repair had clinically significant LUTS due to benign enlargement of prostate (BEP) and required treatment for BEP but none of these 11 patients had urinary symptoms as primary complaint. Ten patients were found to have urinary tract infection without any urinary symptom. Three patients had urethral stricture out of which 2 had Qmax of <10 ml/second.Conclusions: Significant number of patients (14 percent) with inguinal hernia had lower urinary tract symptoms. An effort should be made to identify LUTS in patients presenting with inguinal hernia before surgery and treat the cause of LUTS. Ten percent of patients had asymptomatic UTI with AUA score less than 8 but Qmax on uroflowmetry was in between 10-15 ml/second.

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Lower urinary tract symptoms associated with neurological conditions: Observations on a clinical sample of outpatients neurorehabilitation service

Archivio Italiano di Urologia e Andrologia ◽

10.4081/aiua.2015.2.154 ◽

2015 ◽

Vol 87 (2) ◽

pp. 154 ◽

Cited By ~ 5

Author(s):

Fabrizio Torelli ◽

Erica Terragni ◽

Salvatore Blanco ◽

Natale Di Bella ◽

Marco Grasso ◽

...

Keyword(s):

Multiple Sclerosis ◽

Urinary Tract ◽

Lower Urinary Tract Symptoms ◽

Urge Incontinence ◽

Lower Urinary Tract ◽

Clinical Sample ◽

Urinary Symptoms ◽

Urinary Tract Symptoms ◽

Neurological Conditions ◽

Lower Urinary

Objectives: The overall aims of this study were to investigate the lower urinary tract symptoms (LUTS) associated with neurological conditions and their prevalence and impact on a clinical sample of outpatients of a neurorehabilitation service. Materials and methods: We reviewed the files of 132 patients treated in our neurorehabilitation service from December 2012 to December 2013. Patients were divided into several subgroups based on the neurological diagnosis: Multiple Sclerosis (MS), other demyelinating diseases, Peripheral Neuropathy, neurovascular disorders (ND), neoplastic disease, traumatic brain injury (TBI), Parkinson and Parkinsonism, spinal cord injuries (SCI). Urinary status was based on medical evaluations of history of LUTS, type, degree, onset and duration of symptoms. We tried to analyze prevalence, kind of disorder, timing of presentation (if before or after the neurological onset) and eventual persistence of urological disorders (in the main group and in all subgroups). Results: At the time of admission to our rehabilitation service, LUTS were observed in 14 out of 132 cases (11%). A high proportion of these outpatients (64.2%) presented bothersome urinary symptoms such as incontinence, frequency and urgency (storage LUTS). The most frequent symptom was urinary urge incontinence (42.8%). This symptom was found to be prevalent in the multiple sclerosis and neurovascular disorders. In 93% the urinary symptoms arose as a result of neurologic conditions and 78.5% did not present a complete recovery of urological symptoms in spite of improved selfreported functional activity limitations. None of these patients performed urological rehabilitation. Conclusions: Neurological disorders are a significant issue in rehabilitation services and it can lead to lower tract dysfunction, which causes LUTS. Storage symptoms are more common, especially urge incontinence. Current literature reports that a further optimization of the rehabilitation potential of neurologically ill patients is possible through an implementation of urological basic measures into the neurological treatment routine.

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Cystoscopic Findings in Women with Minimal and Maximal Lower Urinary Tract Symptoms

10.21203/rs.3.rs-124452/v1 ◽

2020 ◽

Author(s):

Ioana Marcu ◽

Jeffrey Gavard ◽

Golnar Varizabadi ◽

Joe Shi ◽

Andrew Steele ◽

...

Keyword(s):

Urinary Tract ◽

Interstitial Cystitis ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Urinary Symptoms ◽

Bladder Pain ◽

Asymptomatic Patients ◽

Urinary Tract Symptoms ◽

Objective Evidence ◽

Lower Urinary

Abstract Background: Glomerulations are not specific for interstitial cystitis/bladder pain syndrome (IC/BPS). Controversy exists about whether cystoscopic findings differ between patients with and without lower urinary tract symptoms. We sought to compare the prevalence of cystoscopic findings in women with “no or minimal” urinary symptoms to those with a “high” symptom burden. Methods: This is a prospective cohort study performed at a University Educational Facility. Participants in this study were part of a larger prospective study, in which female patients scheduled to undergo routine gynecologic procedures were all consented for cystoscopy with hydrodistension (CWHD). We defined the “minimally symptomatic group” as those with <1 on each of the O’Leary/Sant Interstitial Cystitis Symptom Index (ICSI) subscores and without history of IC/BPS. The “highly symptomatic” cohort of women had composite ICSI score > 12 and a Burning/Pain subscore of 4 or 5. All were non-smokers. Results: 84 women underwent CWHD, with 33 having minimal symptoms and 51 being highly symptomatic. The two groups were not statistically different when assessing for ‘any glomerulations’ compared to ‘no glomerulations.’ However, minimally symptomatic women had an eight-fold lower prevalence of significant glomerulations than highly symptomatic women 3.0% versus 23.5% vs 3.0%, p< 0.05. Pairwise comparisons showed significant differences between > 10 glomerulations in 3 or 4 quadrants and no glomerations, with 4% of minimally symptomatic women having > 10 glomerulations in 3 or 4 quadrants versus 28.6% of highly symptomatic women having > 10 glomerations in 3 or 4 quadrants (p<0.05). Conclusion: Extensive glomerulations (>10 in 3 or 4 quadrants) are rare in women without urinary symptoms. These findings contrast with prior limited prospective data which quoted similar incidence of glomerulations in IC/BPS patients and asymptomatic patients. This study highlights the importance of evaluating objective evidence on CWHD and merits further investigation.

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Triptorelin for the relief of lower urinary tract symptoms in men with advanced prostate cancer: results of a prospective, observational, grouped-analysis study

Therapeutic Advances in Urology ◽

10.1177/1756287217712379 ◽

2017 ◽

Vol 9 (7) ◽

pp. 179-190 ◽

Cited By ~ 3

Author(s):

Thierry Gil ◽

Fouad Aoun ◽

Patrick Cabri ◽

Valérie Perrot ◽

Roland van Velthoven

Keyword(s):

Prostate Cancer ◽

Urinary Tract ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Specific Antigen ◽

Urinary Symptoms ◽

Release Formulation ◽

Extended Release Formulation ◽

Urinary Tract Symptoms ◽

Lower Urinary

Background: Lower urinary tract symptoms (LUTSs) may develop in men with prostate cancer (PCa) and can impact quality of life (QoL). Gonadotropin-releasing hormone (GnRH) agonists as androgen deprivation therapy are standard treatment for PCa, however, data are limited on their effects on LUTSs. A grouped analysis of national observational, non-interventional studies initiated in clinical practice was performed to assess the effectiveness of triptorelin in reducing moderate or severe LUTSs, measured using the International Prostate Symptom Score (IPSS) in men with advanced or metastatic PCa. Methods: Men with PCa and LUTSs scheduled to receive triptorelin (3-month or 1-month extended release formulation) were recruited into prospective, non-interventional studies at centres in Algeria, Australia, Belgium, China, Hungary, Romania and South Korea. The primary effectiveness endpoint was the proportion of patients with moderate or severe LUTSs, assessed by IPSS, after 48 weeks. Secondary endpoints included: total IPSS, QoL due to urinary symptoms (IPSS Question 8) and prostate-specific antigen (PSA) levels at 24 and 48 weeks. Results: A total of 2701 patients were recruited; 1851 patients with moderate or severe LUTSs at baseline (IPSS > 7), received triptorelin and had follow-up IPSS (efficacy population). The proportion of patients with moderate or severe LUTSs was reduced to 67.2% from baseline at week 48, following a reduction to 75.9% at week 24: the overall time effect was significant ( p < 0.001). QoL due to urinary symptoms significantly improved from a mean score of 3.7 at baseline, to adjusted means of 2.5 and 2.1, at weeks 24 and 48, respectively ( p < 0.001 versus baseline). Mean PSA levels were reduced from 158.8 ng/ml at baseline to 11.5 and 16.0 ng/ml at weeks 24 and 48, respectively. Conclusions: Within the limitations of these observational studies, improvements in LUTSs and QoL observed after 24 weeks and maintained at 48 weeks indicate that triptorelin-induced effects improve LUTSs in patients with advanced PCa.

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