Intracranial hemorrhage in infants as a serious, and preventable consequence of late form of vitamin K deficiency: a selfie picture of Turkey, strategies for tomorrow

2014 ◽  
Vol 30 (8) ◽  
pp. 1375-1382 ◽  
Author(s):  
Ekrem Unal ◽  
Serkan Ozsoylu ◽  
Ayse Bayram ◽  
Mehmet Akif Ozdemir ◽  
Ebru Yilmaz ◽  
...  
2017 ◽  
Vol 37 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Sudhir Adhikari ◽  
Eva Gauchan ◽  
Tejesh Malla ◽  
Brijesh Sathian ◽  
Kalipatanam Seshagiri Rao

Vitamin K deficiency bleeding (VKDB) can manifest as intracranial hemorrhage (ICH) and is still prevalent in poor resource countries. Infants aged one to twelve months with the diagnosis of ICH from 1st July 2011 to 30th June 2016 were included. There were 16 cases of ICH attributed to vitamin K deficiency. Clinical presentations were anemia16 (100%), bulged fontanel 13(81.3%), seizures 10(62.5%), vomiting 8(50%) and fever 9(56.3%). Mean INR at admission was 8.575±7.267 and 1.868±0.838 after three doses of vitamin K administration. Sites of intracranial bleed were parenchymal 5(31.3%), subdural 4(25%), extradural 2(12.5%), ventricular 2(12.5%). In 3(18.8%) of cases bleeding was more extensive involving more than one site. Mortality was 4(25%) and 3(18.8%) had abnormal neurological findings at discharge. There is an urgent need for national policy for vitamin K prophylaxis at birth.


2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Boonchai Boonyawat ◽  
Yiwa Suksawat ◽  
Punchama Pacharn ◽  
Piradee Suwanpakdee ◽  
Chanchai Traivaree

Vitamin K deficiency bleeding (VKDB) is a life-threatening condition and can be found in children as early as neonatal period with early onset intracranial hemorrhage (ICH). Here, we reported a 1-year-old boy who initially presented with intracranial hemorrhage secondary to vitamin K deficiency since 3 months of age and later found to have XL-CGD which was complicated by malabsorption due to severe vaccine-associated mycobacterial disease.


2012 ◽  
Vol 54 (4) ◽  
pp. 552-557 ◽  
Author(s):  
Fatima S. Alatas ◽  
Makoto Hayashida ◽  
Toshiharu Matsuura ◽  
Isamu Saeki ◽  
Yusuke Yanagi ◽  
...  

2007 ◽  
Vol 14 (5) ◽  
pp. 323-329 ◽  
Author(s):  
Mikiko Miyasaka ◽  
Shunsuke Nosaka ◽  
Hirokazu Sakai ◽  
Yoshiyuki Tsutsumi ◽  
Masayuki Kitamura ◽  
...  

2018 ◽  
Vol 45 (2) ◽  
pp. 461-465 ◽  
Author(s):  
Genichiro Sotodate ◽  
Atsushi Matsumoto ◽  
Yu Konishi ◽  
Yukiko Toya ◽  
Mikiya Endo ◽  
...  

PEDIATRICS ◽  
1984 ◽  
Vol 74 (2) ◽  
pp. 315-316
Author(s):  
TAKESHI NAGAO ◽  
KENTARO NAKAYAMA

To the Editor.— Lane et al1 reported a case of fatal intracranial hemorrhage in a normal infant who was retrospectively determined to have had vitamin K deficiency. This paper rings the alarm against the tendency toward cessation of routine prophylactic administration of vitamin K at birth for full-term infants. We support this opinion because there are many cases of intracranial hemorrhage due to "idiopathic" vitamin K deficiency in infancy in Japan and this may be related to abandonment of routine vitamin K administration at birth.


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