Immunogold and freeze etch electron microscopic studies of merosin localization in basal lamina of human skeletal muscle fibers

1997 ◽  
Vol 93 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Y. Wakayama ◽  
Makoto Murahashi ◽  
Takahiro Jimi ◽  
Hiroko Kojima ◽  
Seiji Shibuya ◽  
...  
1990 ◽  
Vol 13 (5) ◽  
pp. 376-380 ◽  
Author(s):  
Stirling Carpenter ◽  
George Karpati ◽  
Elizabeth Zubrzycka-Gaarn ◽  
Dennis E. Bulman ◽  
Peter N. Ray ◽  
...  

1973 ◽  
Vol 344 (1) ◽  
pp. 1-12 ◽  
Author(s):  
P. D. Gollnick ◽  
R. B. Armstrong ◽  
C. W. Saubert ◽  
W. L. Sembrowich ◽  
R. E. Shepherd ◽  
...  

2000 ◽  
Vol 279 (5) ◽  
pp. E1191-E1195 ◽  
Author(s):  
M. Gaster ◽  
J. Franch ◽  
P. Staehr ◽  
H. Beck-Nielsen ◽  
T. Smith ◽  
...  

Prompted by our recent observations that GLUT-1 is expressed in fetal muscles, but not in adult muscle fibers, we decided to investigate whether GLUT-1 expression could be reactivated. We studied different stimuli concerning their ability to induce GLUT-1 expression in mature human skeletal muscle fibers. Metabolic stress (obesity, non-insulin-dependent diabetes mellitus), contractile activity (training), and conditions of de- and reinnervation (amyotrophic lateral sclerosis) could not induce GLUT-1 expression in human muscle fibers. However, regenerating muscle fibers in polymyositis expressed GLUT-1. In contrast to GLUT-1, GLUT-4 was expressed in all investigated muscle fibers. Although the significance of GLUT-1 in adult human muscle fibers appears limited, GLUT-1 may be of importance for the glucose supplies in immature and regenerating muscle.


Sign in / Sign up

Export Citation Format

Share Document