Compound lesion of a basal cell carcinoma and a malignant melanoma: Is there a common genetic origin?

2014 ◽  
Vol 272 (2) ◽  
pp. 505-509
Author(s):  
Shachi Jenny Sharma ◽  
M. Kreisel ◽  
C. Holler ◽  
T. Kroll ◽  
U. Gamerdinger ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Genetic Origin

scholarly journals Colonisation of basal cell carcinoma and actinic keratosis by malignant melanoma in situ in a patient with xeroderma pigmentosum variant

2012 ◽  
Vol 2 (2) ◽  
pp. 47 ◽  
Author(s):  
Louise J. Smith ◽  
Ehab A. Husain
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Actinic Keratosis ◽  
Xeroderma Pigmentosum ◽  
Clinical Impression ◽  
Anatomical Site ◽  
History Of

Although malignant melanoma (MM) and both basal cell carcinoma (BCC) and actinic keratosis (AK) are sun-induced lesions, the coexistence of these entities at the same anatomical site (collision tumour) is exceedingly rare. We report the case of a 54-year-old woman with a known history of xeroderma pigmentosum variant (XPV) who presented with 2 separate skin lesions over the middle and upper right forearm, respectively. The clinical impression was that of BCCs or squamous cell lesions. On histological examination, both specimens showed features of melanoma <em>in situ </em>(MIS). In the first lesion, MIS merged with and colonised a superficial and focally invasive BCC. In the second lesion, MIS merged with an AK. No separate invasive nests of malignant melanoma were seen in either specimen. The atypical melanocytes were highlighted by Melan-A and HMB-45 immunostaining, whereas the epithelial cells in both the BCC and AK stained with the pancytokeratin MNF-116. The patient had a previous history of multiple MMs and non-melanomatous skin cancers and finally developed widespread metastatic malignant melanoma, which proved fatal. The rare and interesting phenomenon of collision tumours may pose diagnostic difficulties. To our knowledge, this is the first reported simultaneous presentation of cytologically malignant collision tumours in a patient with XPV.

Collision Tumor of Cutaneous Malignant Melanoma and Basal Cell Carcinoma

1998 ◽  
Vol 194 (9) ◽  
pp. 649-653 ◽  
Author(s):  
Eiichiro Hirakawa ◽  
Hiroshi Miki ◽  
Shoji Kobayashi ◽  
Yuri Nomura ◽  
Masaki Ohmori
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Collision Tumor ◽  
Cutaneous Malignant Melanoma

scholarly journals Apoptotic and mitotic indices in malignant melanoma and basal cell carcinoma.

1995 ◽  
Vol 48 (3) ◽  
pp. 242-244 ◽  
Author(s):  
E E Mooney ◽  
J M Ruis Peris ◽  
A O'Neill ◽  
E C Sweeney
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell

scholarly journals Malignant melanoma and basal cell carcinoma in a combined tumour

1999 ◽  
Vol 140 (2) ◽  
pp. 360-360 ◽  
Author(s):  
De Almeida Barbosa jr ◽  
Sales Guimarães ◽  
De Lourdes Lopes ◽  
Sadigursky ◽  
Bittencourt
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell

scholarly journals Malignant melanoma and basal cell carcinoma detection with 457 nm laser-induced fluorescence

2015 ◽  
pp. 180-185 ◽  
Author(s):  
Ivan Bratchenko ◽  
Dmitry Artemyev ◽  
Oleg Myakinin ◽  
Maria Vrakova ◽  
Kirill Shpuntenko ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Laser Induced Fluorescence
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