scholarly journals Risk factors, aetiology and outcome of ischaemic stroke in young adults: the Swiss Young Stroke Study (SYSS)

2015 ◽  
Vol 262 (9) ◽  
pp. 2025-2032 ◽  
Author(s):  
Barbara Goeggel Simonetti ◽  
Marie-Luise Mono ◽  
Uyen Huynh-Do ◽  
Patrik Michel ◽  
Celine Odier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Young Stroke ◽  
Stroke In Young Adults ◽  
Stroke Study ◽  
Stroke In Young

scholarly journals Erratum to: Risk factors, aetiology and outcome of ischaemic stroke in young adults: the Swiss Young Stroke Study (SYSS)

2015 ◽  
Vol 263 (1) ◽  
pp. 199-200 ◽  
Author(s):  
Barbara Goeggel Simonetti ◽  
Marie-Luise Mono ◽  
Uyen Huynh-Do ◽  
Patrik Michel ◽  
Celine Odier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Young Stroke ◽  
Stroke In Young Adults ◽  
Stroke Study ◽  
Stroke In Young

Traditional Risk Factors and Ischemic Stroke in Young Adults: The Baltimore-Washington Cooperative Young Stroke Study

1996 ◽  
Vol 53 (7) ◽  
pp. 603-607 ◽  
Author(s):  
J. Rohr ◽  
S. Kittner ◽  
B. Feeser ◽  
J. R. Hebel ◽  
M.-G. Whyte ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischemic Stroke ◽  
Young Stroke ◽  
Stroke In Young Adults ◽  
Stroke Study ◽  
Traditional Risk Factors ◽  
Stroke In Young

Ischaemic stroke in young adults: risk factors and long-term consequences

2014 ◽  
Vol 10 (6) ◽  
pp. 315-325 ◽  
Author(s):  
Noortje A. M. M. Maaijwee ◽  
Loes C. A. Rutten-Jacobs ◽  
Pauline Schaapsmeerders ◽  
Ewoud J. van Dijk ◽  
Frank-Erik de Leeuw
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Stroke In Young Adults ◽  
Long Term Consequences ◽  
Stroke In Young

scholarly journals Global Outcome Assessment Life-long after stroke in young adults initiative—the GOAL initiative: study protocol and rationale of a multicentre retrospective individual patient data meta-analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e031144
Author(s):  
Merel Ekker ◽  
Mina Jacob ◽  
Myrna van Dongen ◽  
Karoliina Aarnio ◽  
Arunkar Annamalai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Secondary Prevention ◽  
Stroke Risk ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Stroke Patients ◽  
Young Stroke ◽  
Stroke In Young Adults ◽  
Stroke In Young

IntroductionWorldwide, 2 million patients aged 18–50 years suffer a stroke each year, and this number is increasing. Knowledge about global distribution of risk factors and aetiologies, and information about prognosis and optimal secondary prevention in young stroke patients are limited. This limits evidence-based treatment and hampers the provision of appropriate information regarding the causes of stroke, risk factors and prognosis of young stroke patients.Methods and analysisThe Global Outcome Assessment Life-long after stroke in young adults (GOAL) initiative aims to perform a global individual patient data meta-analysis with existing data from young stroke cohorts worldwide. All patients aged 18–50 years with ischaemic stroke or intracerebral haemorrhage will be included. Outcomes will be the distribution of stroke aetiology and (vascular) risk factors, functional outcome after stroke, risk of recurrent vascular events and death and finally the use of secondary prevention. Subgroup analyses will be made based on age, gender, aetiology, ethnicity and climate of residence.Ethics and disseminationEthical approval for the GOAL study has already been obtained from the Medical Review Ethics Committee region Arnhem-Nijmegen. Additionally and when necessary, approval will also be obtained from national or local institutional review boards in the participating centres. When needed, a standardised data transfer agreement will be provided for participating centres. We plan dissemination of our results in peer-reviewed international scientific journals and through conference presentations. We expect that the results of this unique study will lead to better understanding of worldwide differences in risk factors, causes and outcome of young stroke patients.

scholarly journals Ischaemic stroke in young adults: a global perspective

2020 ◽  
Vol 91 (4) ◽  
pp. 411-417 ◽  
Author(s):  
Esther Boot ◽  
Merel Sanne Ekker ◽  
Jukka Putaala ◽  
Steven Kittner ◽  
Frank-Erik De Leeuw ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Developed Countries ◽  
Social Consequences ◽  
Global Perspective ◽  
High Morbidity ◽  
Stroke In Young Adults ◽  
Rising Incidence ◽  
Stroke In Young

Ischaemic stroke at young age is an increasing problem in both developing and developed countries due to rising incidence, high morbidity and mortality and long-term psychological, physical and social consequences. Compared with stroke in older adults, stroke in young adults is more heterogeneous due to the wide variety of possible underlying risk factors and aetiologies. In this review, we will provide an overview of the global variation in the epidemiology of stroke in young adults, with special attention to differences in geography, ethnicity/race and sex, as well as traditional and novel risk factors for early-onset ischaemic stroke, such as air pollution. Understanding global differences is an important prerequisite for better region-specific prevention and treatment of this devastating condition.

scholarly journals Erratum: Ischaemic stroke in young adults: risk factors and long-term consequences

2014 ◽  
Vol 10 (11) ◽  
pp. 612-612
Author(s):  
Noortje A. M. M. Maaijwee ◽  
Loes C. A. Rutten-Jacobs ◽  
Pauline Schaapsmeerders ◽  
Ewoud J. van Dijk ◽  
Frank-Erik de Leeuw
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Stroke In Young Adults ◽  
Long Term Consequences ◽  
Stroke In Young

scholarly journals Risk factors for acute ischaemic stroke in young adults in South India

2007 ◽  
Vol 78 (9) ◽  
pp. 959-963 ◽  
Author(s):  
K Lipska ◽  
P N Sylaja ◽  
P S Sarma ◽  
K R Thankappan ◽  
V R Kutty ◽  
...  
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Ischaemic Stroke ◽  
Acute Ischaemic Stroke ◽  
South India ◽  
Stroke In Young Adults ◽  
Stroke In Young

scholarly journals Epidemiology and characteristics of ischaemic stroke in young adults in Aragon

2021 ◽  
Author(s):  
H. Tejada Meza ◽  
J. Artal Roy ◽  
C. Pérez Lázaro ◽  
M. Bestué Cardiel ◽  
O. Alberti González ◽  
...  
Keyword(s):  
Young Adults ◽  
Ischaemic Stroke ◽  
Stroke In Young Adults ◽  
Stroke In Young

scholarly journals Prevalence and outcome of young stroke patients with middle cerebral artery stenosis

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wenjuan Xu ◽  
Xiaoyu Zhang ◽  
Huan Chen ◽  
Zhangning Zhao ◽  
Meijia Zhu
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Risk Factor ◽  
Factor Score ◽  
Unfavorable Outcome ◽  
Stroke Patients ◽  
Young Stroke ◽  
Stroke In Young Adults ◽  
Risk Factor Score ◽  
Stroke In Young

Abstract Background Etiologies of acute ischemic stroke in young adults are heterogeneous. Middle cerebral artery (MCA) stenosis is a common finding in Asians which may be an important cause of stroke in young adults. However, studies of stroke in young Asian populations are rare. Our study was to investigate the prevalence and outcome of young stroke patients with MCA stenosis in Chinese populations. Methods Young patients with MCA territory infarction between January 2013 and September 2018 were retrospectively recruited. Subjects were defined as stenosis group (MCA stenosis ≥50%) and no-stenosis group (MCA stenosis<50% or no stenosis) by their MCA stenosis. For patients in stenosis group, they were categorized as uni-MCA stenosis subgroup and multiple stenosis subgroup. Demographic data, risk factors, imaging feature and complications were compared between groups. Prevalence of MCA stenosis and risk factor score (score ≥ 2 or 3) in different age groups were investigated. Modified Rankin Scale (mRS) was used for evaluating functional outcome at discharge (unfavorable outcome: 3–6). Binary logistic regression was performed to determine independent risk factors of unfavorable outcome. Results Two hundred forty-nine young stroke patients were included in our study and 110 (44.2%) patients were defined as stenosis group. 55 (50%) patients were categorized as uni-MCA stenosis subgroup and 55 (50%) were multiple stenosis subgroup. The most common traditional vascular risk factors included hypertension, hyperlipemia, smoking, hyperhomocysteinemia and alcohol consumption. Prevalence of risk factor score ≥ 2 or 3 increased with age, but not incidence of MCA stenosis. By TOAST classification, the most common etiologies were large-artery atherosclerosis (41.0%) and small vessel disease (33.7%). Compared with no-stenosis group, patients in stenosis group were more likely to have large territorial infarct, develop complications and have unfavorable outcome. No significant difference was found between patients in uni-MCA stenosis and multiple stenosis subgroups except history of stroke/TIA, risk factor score ≥ 3 and silent infarct. By logistic regression, hypertension (OR = 3.561; 95%CI, 1.494 to 8.492; p = 0.004), NIHSS scores at admission (OR = 1.438; 95%CI, 1.276 to 1.620; p = 0,000) and infarct size (p = 0.015) independently predicted unfavorable outcome. Conclusions Forty-four point two percent young Chinese adults with MCA territory infarction had MCA stenosis. Prevalence of MCA stenosis did not increase with age. Patients with MCA stenosis had worse clinical outcome, however, only hypertension, NIHSS scores at admission and infarct size were independent predictors.

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