Guillain-Barre Syndrome (GBS) is a post-infectious neuropathy
typically described as a bilateral ascending paralysis of the lower
extremities. There are, however, multiple lesser known subtypes of
the syndrome that can affect both adult and pediatric populations.
The Pharyngeal- Brachial-Cervical (PCB) variant is one of the rarer
forms, which presents with weakness of the neck, oropharynx, and
upper extremities. This atypical presentation can be confused with
other diagnoses, and early detection is important for preventing
potentially life-threatening complications. To date, only ten cases
of this entity have been reported in children. Below we report on
a 15-year-old female who presented with left arm weakness who
subsequently progressed to classic GBS and review the literature
on this GBS variant in children.