Skin absorption of the industrial catalyst dimethylethylamine in vitro in guinea pig and human skin, and of gaseous dimethylethylamine in human volunteers

1997 ◽  
Vol 70 (5) ◽  
pp. 309-313 ◽  
Author(s):  
Thomas Lundh ◽  
Anders Boman ◽  
Bengt Åkesson
Keyword(s):  
Guinea Pig ◽  
Human Skin ◽  
Skin Absorption ◽  
Industrial Catalyst ◽  
Human Volunteers

Use of a Simple in vitro Test to Assess Loss of Chemical due to Volatility during an in vitro Human Skin Absorption Study

2019 ◽  
Vol 32 (3) ◽  
pp. 117-124 ◽  
Author(s):  
Sébastien Grégoire ◽  
Richard Cubberley ◽  
Hélène Duplan ◽  
Joan Eilstein ◽  
Nicola J. Hewitt ◽  
...  
Keyword(s):  
Human Skin ◽  
In Vitro Test ◽  
Skin Absorption ◽  
Absorption Study ◽  
Vitro Test

scholarly journals Anti-Aging Potential of Substance P-Based Hydrogel for Human Skin Longevity

2019 ◽  
Vol 20 (18) ◽  
pp. 4453 ◽  
Author(s):  
Da Jung Kim ◽  
Song Sun Chang ◽  
Jungsun Lee
Keyword(s):  
Substance P ◽  
Human Skin ◽  
Collagen Synthesis ◽  
Skin Penetration ◽  
Dermal Fibroblasts ◽  
Toxicity Tests ◽  
Skin Absorption ◽  
Collagen Production ◽  
Anti Inflammatory

Skin aging is generally caused by a decline in the components of the extracellular matrix (e.g., collagen and elastin) and due to inflammatory phenomena. Many growth factors and peptides with cell-growth and collagen-synthesis activities have shown promise in their application in anti-aging materials. However, the effect of collagen production, without anti-inflammatory effect, and skin penetration may not be enough for their use in anti-aging agents. Previously, we reported a substance P (SP)-based hydrogel (SP gel) that had potential wound-healing activities via induction of skin cell regeneration and collagen synthesis. Here, we analyzed the anti-aging activities and skin absorption effects of SP gel to extend its characterization. Toxicity tests, performed on human dermal fibroblasts (HDFs) and on a reconstructed 3D human skin model, indicated SP gel to be safe for long-term use, without causing irritation, even at high concentrations. In-vitro analysis revealed that SP gel elicited stronger collagen production activities than SP alone, and promoted anti-inflammatory effects with increased skin absorption properties. Moreover, SP gel did not induce melanin synthesis in a keratinocyte-melanocyte co-culture system. Together, the results suggest that SP gel has potential cosmetic effects and applicability as a novel ingredient in anti-aging products.

In Vitro Human Skin Absorption of Solvent-Deposited Solids: Niacinamide and Methyl Nicotinate

2021 ◽  
Author(s):  
Gerald B. Kasting ◽  
Matthew A. Miller ◽  
Lijing Xu ◽  
Fang Yu ◽  
Joanna Jaworska
Keyword(s):  
Human Skin ◽  
Skin Absorption ◽  
Methyl Nicotinate

An FTIR investigation of isocyanate skin absorption using in vitro guinea pig skin

2006 ◽  
Vol 8 (5) ◽  
pp. 523 ◽  
Author(s):  
Dhimiter Bello ◽  
Thomas J. Smith ◽  
Susan R. Woskie ◽  
Robert P. Streicher ◽  
Mark F. Boeniger ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Skin Absorption ◽  
Pig Skin ◽  
Ftir Investigation

Human skin absorption of bis-2-(chloroethyl)sulphide (sulphur mustard)in vitro

2000 ◽  
Vol 20 (5) ◽  
pp. 349-355 ◽  
Author(s):  
R. P. Chilcott ◽  
J. Jenner ◽  
W. Carrick ◽  
S. A. M. Hotchkiss ◽  
P. Rice
Keyword(s):  
Human Skin ◽  
Skin Absorption ◽  
Sulphur Mustard

In vitro degradation of the stereoisomers of soman in guinea-pig, mouse and human skin

1989 ◽  
Vol 38 (14) ◽  
pp. 2263-2268 ◽  
Author(s):  
Cornelia J. van Dongen ◽  
Jan de Lange ◽  
John van Genderen
Keyword(s):  
Guinea Pig ◽  
Human Skin ◽  
In Vitro Degradation
Sign in / Sign up

Export Citation Format

Share Document