Motor cortex excitability changes preceding voluntary muscle activity in simple reaction time task

2006 ◽  
Vol 98 (2) ◽  
pp. 212-219 ◽  
Author(s):  
M. Nikolova ◽  
N. Pondev ◽  
L. Christova ◽  
W. Wolf ◽  
A. R. Kossev
2009 ◽  
Vol 101 (6) ◽  
pp. 2859-2871 ◽  
Author(s):  
Nandakumar S. Narayanan ◽  
Mark Laubach

To understand how different parts of the frontal cortex control the timing of action, we characterized the firing patterns of single neurons in two areas of rodent frontal cortex—dorsomedial prefrontal cortex (dmPFC) and motor cortex—during a simple reaction time task. Principal component analysis was used to identify major patterns of delay-related activity in frontal cortex: ramping activity and sustained delay activity. These patterns were similar in dmPFC and motor cortex and did not change as animals learned to respond at novel delays. Many neurons in both areas were modulated early in the delay period. Other neurons were modulated in a persistent manner over the duration of the delay period. Delay-related modulations started earlier in motor cortex than in dmPFC and terminated around different task events (at the time of release in dmPFC, just before release of the lever in motor cortex). A subpopulation of neurons was found in dmPFC, but not motor cortex, that fired in response to the trigger stimulus. These results suggest that populations of neurons in rodent frontal cortex are coordinated during delay periods to enable proactive inhibitory control of action.


1976 ◽  
Vol 16 (3) ◽  
pp. 311-315 ◽  
Author(s):  
Patricia T. Michie ◽  
Alex M. Clarke ◽  
John D. Sinden ◽  
Leonard C.T. Glue

1999 ◽  
Vol 128 (1-2) ◽  
pp. 256-261 ◽  
Author(s):  
Gregor Thut ◽  
Claude-Alain Hauert ◽  
Stéphanie Morand ◽  
Margitta Seeck ◽  
Theodor Landis ◽  
...  

1991 ◽  
Vol 73 (3) ◽  
pp. 863-866 ◽  
Author(s):  
Jos J. Adam ◽  
Loe M. A. Van Veggel

The present study evaluated the potential for neuroanatomical factors to operate in a simple reaction time task. That is, response latencies were recorded for all ten fingers on a Donders' A reaction time task. Two finger-placement conditions were used, a single response key condition and a multiple response key condition. This latter condition required subjects to place all ten fingers on response keys. 30 male, right-handed subjects participated. No significant effects were found, indicating that there are no intrinsically slow or fast fingers. This finding is discussed in the context of reaction time differences between individual stimulus-response (finger) pairs in choice-reaction time tasks.


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