Surgical strategy for T2 and T3 gallbladder cancer: is extrahepatic bile duct resection always necessary?

2013 ◽  
Vol 398 (8) ◽  
pp. 1137-1144 ◽  
Author(s):  
Sae Byeol Choi ◽  
Hyung Joon Han ◽  
Wan Bae Kim ◽  
Tae Jin Song ◽  
Sung Ock Suh ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Extrahepatic Bile Duct ◽  
Surgical Strategy ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection

Indication of extrahepatic bile duct resection for gallbladder cancer

2017 ◽  
Vol 403 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Hiroshi Kurahara ◽  
Kosei Maemura ◽  
Yuko Mataki ◽  
Masahiko Sakoda ◽  
Satoshi Iino ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Extrahepatic Bile Duct ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection

Clinical significance of extrahepatic bile duct resection for advanced gallbladder cancer

2006 ◽  
Vol 94 (4) ◽  
pp. 298-306 ◽  
Author(s):  
Yoshihiro Sakamoto ◽  
Tomoo Kosuge ◽  
Kazuaki Shimada ◽  
Tsuyoshi Sano ◽  
Taizo Hibi ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Clinical Significance ◽  
Extrahepatic Bile Duct ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection ◽  
Advanced Gallbladder Cancer

scholarly journals Indications for extrahepatic bile duct resection due to perineural invasion in patients with gallbladder cancer

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Suguru Maruyama ◽  
Hiromichi Kawaida ◽  
Naohiro Hosomura ◽  
Hidetake Amemiya ◽  
Ryo Saito ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Perineural Invasion ◽  
Extrahepatic Bile Duct ◽  
Lymphatic Invasion ◽  
Prognostic Impact ◽  
Clinicopathological Factors ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection ◽  
Male Sex

Abstract Background The indications for extrahepatic bile duct (EHBD) resection remain a major controversy in the surgical management of patients with gallbladder cancer. On the other hand, perineural invasion (PNI) was reported as an important factor in patients with gallbladder cancer because gallbladder cancer cells frequently spread to the tissues surrounding the EHBD via perineural routes. We assessed the correlation of PNI with clinicopathological factors in patients with gallbladder cancer to elucidate EHBD resection indications specifically in patients with PNI. Methods This retrospective study assessed the PNI status of 50 patients with gallbladder cancer who underwent curative resection and examined the correlation between the presence of PNI and clinicopathological factors. Results Thirteen patients (26%) were PNI positive. PNI was significantly correlated with male sex, proximal-type tumor, lymphatic and vascular invasion, and advanced T stage. Multivariate analysis found that PNI positivity (p < 0.001), lymphatic invasion (p = 0.007), and nodal stage (p < 0.001) were independent prognostic factors. PNI was never observed in patients with stage T1 cancer. Conversely, PNI was detected rarely in distal-type tumors, all of whom developed various types of recurrences. Conclusions These results clearly demonstrated the prognostic impact of PNI in patients with gallbladder cancer. We suggest that EHBD resection in combination with cholecystectomy may not be useful for distal-type tumors from a perspective of PNI.

scholarly journals Patterns of recurrence after resection of gallbladder cancer without routine extrahepatic bile duct resection

HPB ◽  
2014 ◽  
Vol 16 (7) ◽  
pp. 635-640 ◽  
Author(s):  
Jimme K. Wiggers ◽  
Bas Groot Koerkamp ◽  
Zachri Ovadia ◽  
Olivier R.C. Busch ◽  
Dirk J. Gouma ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Extrahepatic Bile Duct ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection ◽  
Patterns Of Recurrence

scholarly journals A case with massive hemobilia long-term after internal drainage surgery for congenital biliary dilation

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Shunryo Minezaki ◽  
Takeyuki Misawa ◽  
Makoto Watanabe ◽  
Hideki Takahashi ◽  
Takashi Koenuma ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gastrointestinal Bleeding ◽  
Pathological Condition ◽  
Extrahepatic Bile Duct ◽  
Pathological Examination ◽  
Emergency Setting ◽  
Internal Drainage ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection ◽  
Life Threatening

Abstract Background Currently, there is an unwavering consensus that the standard surgery for congenital biliary dilation (CBD) is extrahepatic bile duct resection and choledochojejunostomy. However, decades prior, choledochocyst–gastrointestinal anastomosis without extrahepatic bile duct resection (internal drainage surgery, IDS) was preferred for CBD because of its simplicity. Currently, there is almost no chance of a surgeon encountering a patient who has undergone old-fashioned IDS, which has been completely obsolete due to the risk of carcinogenesis from the remaining bile duct. Moreover, the pathological condition long after IDS is unclear. Herein, we report a case of life-threatening bile duct bleeding as well as carcinoma of the bile duct 62 years after IDS in a patient with CBD. Case presentation An 82-year-old Japanese woman with hemorrhagic shock due to gastrointestinal bleeding was transferred to our hospital. She had a medical history of unspecified surgery for CBD at the age of 20. Based on imaging findings and an understanding of the historical transition of the surgical procedure for CBD, the cause of gastrointestinal bleeding was determined to be rupture of the pseudoaneurysm of the dilated bile duct that remained after IDS. Hemostasis was successfully performed by transcatheter arterial embolization (TAE) in an emergency setting. Then, elective surgery for extrahepatic bile duct resection and choledochojejunostomy was performed to prevent rebleeding. Pathological examination revealed severely and chronically inflamed mucosa of the bile duct. Additionally, cholangiocarcinoma (Tis, N0, M0, pStage 0) was incidentally revealed. Conclusion It has been indicated that not only carcinogenesis, but also a risk of life-threatening bleeding exists due to long-lasting chronic inflammation to the remnant bile duct after IDS for CBD. Additionally, both knowledge of which CBD operation was performed, and an accurate clinical history are important for the diagnosis of hemobilia.

Discrepancy between volume and functional recovery in early phase liver regeneration following extended hepatectomy with extrahepatic bile duct resection

2019 ◽  
Vol 49 (10) ◽  
pp. 1227-1235 ◽  
Author(s):  
Takashi Maeda ◽  
Yukihiro Yokoyama ◽  
Tomoki Ebata ◽  
Tsuyoshi Igami ◽  
Takashi Mizuno ◽  
...  
Keyword(s):  
Bile Duct ◽  
Liver Regeneration ◽  
Functional Recovery ◽  
Early Phase ◽  
Extrahepatic Bile Duct ◽  
Extended Hepatectomy ◽  
Bile Duct Resection ◽  
Extrahepatic Bile Duct Resection
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