Regulation of the Na + 2Cl - K + cotransporter in in vitro perfused rectal gland tubules of Squalus acanthias

1998 ◽  
Vol 436 (4) ◽  
pp. 521-528 ◽  
Author(s):  
R. Warth ◽  
M. Bleich ◽  
I. Thiele ◽  
F. Lang ◽  
R. Greger
Keyword(s):  
Squalus Acanthias ◽  
Rectal Gland

Mechanism of active chloride secretion by shark rectal gland: role of Na-K-ATPase in chloride transport

1977 ◽  
Vol 233 (4) ◽  
pp. F298-F306 ◽  
Author(s):  
P. Silva ◽  
J. Stoff ◽  
M. Field ◽  
L. Fine ◽  
J. N. Forrest ◽  
...  
Keyword(s):  
Chloride Transport ◽  
Sodium Concentration ◽  
Chloride Secretion ◽  
Squalus Acanthias ◽  
Rectal Gland ◽  
Tentative Hypothesis ◽  
Shark Rectal Gland ◽  
Electrochemical Equilibrium

The isolated rectal gland of Squalus acanthias was stimulated to secrete chloride against an electrical and a chemical gradient when perfused in vitro by theophylline and/or dibutyryl cyclic AMP. Chloride secretion was depressed by ouabain which inhibits Na-K-ATPase. Thiocyanate and furosemide also inhibited chloride secretion but ethoxzolamide, a carbonic anhydrase inhibitor, did not. Chloride transport was highly dependent on sodium concentration in the perfusate. The intracellular concentration of chloride averaged 70-80 meq/liter in intact glands, exceeding the level expected at electrochemical equilibrium and suggesting active transport of chloride into the cell. These features suggest a tentative hypothesis for chloride secretion by the rectal gland in which the uphill transport of chloride into the cytoplasm is coupled through a membrane carrier to the downhill movement of sodium along its electrochemical gradient. The latter is maintained by the Na-K-ATPase pump while chloride is extruded into the duct by electrical forces.

pH-regulatory mechanisms in in vitro perfused rectal gland tubules of Squalus acanthias

1998 ◽  
Vol 436 (2) ◽  
pp. 248-254 ◽  
Author(s):  
M. Bleich ◽  
R. Warth ◽  
I. Thiele ◽  
R. Greger
Keyword(s):  
Squalus Acanthias ◽  
Regulatory Mechanisms ◽  
Rectal Gland

Osmotically Induced Conductance and Capacitance Changes in in vitro Perfused Rectal Gland Tubules of Squalus acanthias

1998 ◽  
Vol 21 (5) ◽  
pp. 317-324 ◽  
Author(s):  
I. Thiele ◽  
R. Warth ◽  
M. Bleich ◽  
S. Waldegger ◽  
F. Lang ◽  
...  
Keyword(s):  
Squalus Acanthias ◽  
Rectal Gland

The effect of organotin compounds on chloride secretion by the in vitro perfused rectal gland of Squalus acanthias

1989 ◽  
Vol 100 (2) ◽  
pp. 307-314 ◽  
Author(s):  
Richard Solomon ◽  
Stephanie Lear ◽  
Robert Cohen ◽  
Kate Spokes ◽  
Patricio Silva ◽  
...  
Keyword(s):  
Chloride Secretion ◽  
Squalus Acanthias ◽  
Organotin Compounds ◽  
Rectal Gland

Potassium channels in the basolateral membrane of the rectal gland of the dogfish (Squalus acanthias)

1987 ◽  
Vol 409 (1-2) ◽  
pp. 100-106 ◽  
Author(s):  
Rainer Greger ◽  
Heinz Gögelein ◽  
Eberhard Schlatter
Keyword(s):  
Potassium Channels ◽  
Basolateral Membrane ◽  
Squalus Acanthias ◽  
Rectal Gland
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