scholarly journals Role of the D2 dopamine receptor in molecular adaptation to chronic hypoxia in PC12 cells

1999 ◽  
Vol 438 (6) ◽  
pp. 750-759 ◽  
Author(s):  
S. Kobayashi ◽  
L. Conforti ◽  
W. H. Zhu ◽  
D. Beitner-Johnson ◽  
D. E. Millhorn
1999 ◽  
Vol 438 (6) ◽  
pp. 750-759 ◽  
Author(s):  
S. Kobayashi ◽  
L. Conforti ◽  
W. H. Zhu ◽  
D. Beitner-Johnson ◽  
D. E. Millhorn

2012 ◽  
Author(s):  
S. Espinoza ◽  
F. Manago ◽  
M. Messa ◽  
T. D. Sotnikova ◽  
M. Caron ◽  
...  

2012 ◽  
Author(s):  
S. Espinoza ◽  
F. Manago ◽  
M. Messa ◽  
T. D. Sotnikova ◽  
M. Caron ◽  
...  

2015 ◽  
Vol 60 (10) ◽  
pp. 2963-2975 ◽  
Author(s):  
Ganna Tolstanova ◽  
Xiaoming Deng ◽  
Amrita Ahluwalia ◽  
Brankica Paunovic ◽  
Alona Prysiazhniuk ◽  
...  

2020 ◽  
Author(s):  
Enrica Montalban ◽  
Albert Giralt ◽  
Lieng Taing ◽  
Yuki Nakamura ◽  
Claire Martin ◽  
...  

ABSTRACTForebrain dopaminoceptive neurons play a key role in movement, action selection, motivation, and working memory. Their activity is dysregulated in addiction, Parkinson’s disease and other conditions. To characterize the diverse dopamine target neuronal populations, we compare translating mRNAs in neurons of dorsal striatum and nucleus accumbens expressing D1 or D2 dopamine receptor and prefrontal cortex expressing D1 receptor. We identify D1/D2 and striatal dorso-ventral differences in the translational and splicing landscapes, which establish the characteristics of dopaminoceptive neurons. Expression differences and network analyses identify novel transcription factors with presumptive roles in these differences. Prostaglandin E2 appears as a candidate upstream regulator in the dorsal striatum, a hypothesis supported by converging functional evidence indicating its role in enhancing D2 dopamine receptor action. Our study provides powerful resources for characterizing dopamine target neurons, new information about striatal gene expression patterns, and reveals the unforeseen role of prostaglandin E2 in the dorsal striatum.


2000 ◽  
Vol 47 (3) ◽  
pp. 369-373 ◽  
Author(s):  
Christine Klein ◽  
Nadia Gurvich ◽  
Miguel Sena-Esteves ◽  
Susan Bressman ◽  
Mitchell F. Brin ◽  
...  

2003 ◽  
Vol 28 (7) ◽  
pp. 1317-1327 ◽  
Author(s):  
Oliver Kudlacek ◽  
Herwig Just ◽  
Vladimir M Korkhov ◽  
Nina Vartian ◽  
Markus Klinger ◽  
...  

1993 ◽  
Vol 21 (2) ◽  
pp. 113S-113S
Author(s):  
ROBERT WOODWARD ◽  
PHILIP G. STRANGE ◽  
LOUISE H. NAYLOR

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