Long-term treatment of persistent hyperinsulinaemic hypoglycaemia of infancy with diazoxide: a retrospective review of 77 cases and analysis of efficacy-predicting criteria

1998 ◽  
Vol 157 (8) ◽  
pp. 628-633 ◽  
Author(s):  
G. Touati ◽  
F. Poggi-Travert ◽  
H. Ogier de Baulny ◽  
J. Rahier ◽  
F. Brunelle ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Term Treatment ◽  
Hyperinsulinaemic Hypoglycaemia ◽  
Long Term Treatment

Long-term treatment with diazoxide in childhood hyperinsulinism

1986 ◽  
Vol 113 (4_Suppl) ◽  
pp. S340-S345 ◽  
Author(s):  
D. B. GRANT ◽  
D. B. DUNGER ◽  
E. C. BURNS
Keyword(s):  
Spontaneous Remission ◽  
Term Treatment ◽  
Hyperinsulinaemic Hypoglycaemia ◽  
Normal Intelligence ◽  
Subtotal Pancreatectomy ◽  
The Third ◽  
Long Term Treatment ◽  
Severe Retardation ◽  
Recurrent Hypoglycaemia

Abstract This paper reviews the outcome in 12 children with hyperinsulinaemic hypoglycaemia who first developed symptoms between the ages of 2 and 8 months and who were treated with diazoxide (5 - 20 mg/kg/day) for 2-13 years. Two cases required subtotal pancreatectomy at the ages of 5 and 10 years because of recurrent hypoglycaemia and one girl with severe retardation died at the age of 6 years while still on diazoxide therapy. Two patients aged 3.5 and 9 years are still on treatment and in 7 cases diazoxide was discontinued between the ages of 2.5 and 14 years, indicating that spontaneous remission can be expected in a high proportion of children with post-neonatal hyperinsulinaemic hypoglycaemia. Of the 9 children who started diazoxide within 3 months of the onset of symptoms, 5 are of normal intelligence and 4 are moderately retarded (IQs 63-71). In 3 children diazoxide was started 8 months to 3 years after the onset of symptoms; two are retarded (IQs 60-70) and the third was severely retarded and died aged 6 years.

PERSISTENT HYPERINSULINAEMIC HYPOGLYCAEMIA OF INFANCY: LONG-TERM TREATMENT WITH THE SOMATOSTATIN ANALOGUE SANDOSTATIN

1989 ◽  
Vol 31 (1) ◽  
pp. 71-80 ◽  
Author(s):  
BENJAMIN GLASER ◽  
HEDDY LANDAU ◽  
ADINA SMILOVICI and ◽  
RAFAEL NESHER
Keyword(s):  
Term Treatment ◽  
Somatostatin Analogue ◽  
Hyperinsulinaemic Hypoglycaemia ◽  
Long Term Treatment

Hypnotherapy is effective in the long-term treatment of functional dyspepsia

2001 ◽  
Vol 120 (5) ◽  
pp. A115-A115 ◽  
Author(s):  
E CALVERT ◽  
L HOUGHTON ◽  
P COOPER ◽  
P WHORWELL
Keyword(s):  
Functional Dyspepsia ◽  
Term Treatment ◽  
Long Term Treatment

1608: Long-Term Treatment with High Doses of Sildenafil Does Not Up-Regulate the Levels of Phosphodiesterase 5 (Pde5) in the Rat Penis

2004 ◽  
Vol 171 (4S) ◽  
pp. 424-424 ◽  
Author(s):  
Monica G. Ferrini ◽  
Eliane G. Valente ◽  
Jacob Rajfer ◽  
Nestor F. Gonzalez-Cadavid
Keyword(s):  
Term Treatment ◽  
Long Term Treatment ◽  
High Doses ◽  
Phosphodiesterase 5

Long-Term Treatment Outcomes for Heroin Dependence: The 11-Year Follow-Up of the ATOS Study

2013 ◽  
Author(s):  
Christina Marel ◽  
Maree Teesson ◽  
Shane Darke ◽  
Katherine Mills ◽  
Joanne Ross ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Term Treatment ◽  
Heroin Dependence ◽  
Long Term Treatment

Relevance of quantitative HBsAg (qHBsAg) during long-term treatment of chronic hepatitis B with nucleos(t)ide analogues (NUCs)

2011 ◽  
Vol 49 (01) ◽  
Author(s):  
J Jaroszewicz ◽  
H Ho ◽  
K Deterding ◽  
A Markova ◽  
K Wursthorn ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Term Treatment ◽  
Long Term Treatment
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