Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas

2008 ◽  
Vol 134 (12) ◽  
pp. 1267-1276 ◽  
Author(s):  
Davut Pehlivan ◽  
Esra Gunduz ◽  
Mehmet Gunduz ◽  
Hitoshi Nagatsuka ◽  
Levent Bekir Beder ◽  
...  
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Poor Prognosis ◽  
Squamous Cell Carcinomas ◽  
Chromosome 14Q

scholarly journals Loss of Heterozygosity of 3p21 and 9p21 in Head and Neck Squamous Cell Carcinomas and its Prognostic Implication.

1999 ◽  
Vol 102 (5) ◽  
pp. 613-621 ◽  
Author(s):  
Kazuto Matsuura ◽  
Kiyoto Shiga ◽  
Junkichi Yokoyama ◽  
Masaru Tateda ◽  
Hiroshi Nakano ◽  
...  
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Prognostic Implication

scholarly journals Genome-Wide Analyses on Loss of Heterozygosity in Head and Neck Squamous Cell Carcinomas

2003 ◽  
Vol 83 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Levent Bekir Beder ◽  
Mehmet Gunduz ◽  
Mamoru Ouchida ◽  
Kunihiro Fukushima ◽  
Esra Gunduz ◽  
...  
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Genome Wide

scholarly journals Genome-wide Loss of Heterozygosity Analysis in Head and Neck Squamous Cell Carcinomas

2005 ◽  
Vol 14 (2) ◽  
pp. 229-231
Author(s):  
Levent Beder ◽  
Mehmet Gunduz ◽  
Keihachi Fukunishi ◽  
Yumiko Hiura ◽  
Kazunori Nishizaki ◽  
...  
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Genome Wide

Loss of heterozygosity studies in squamous cell carcinomas of the head and neck

Head & Neck ◽  
1996 ◽  
Vol 18 (3) ◽  
pp. 248-253 ◽  
Author(s):  
David T. Ransom ◽  
J. Helen Leonard ◽  
John H. Kearsley ◽  
Gavin R. Turbett ◽  
Kathy Heel ◽  
...  
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas

scholarly journals Endogenously-Activated Ultrasmall-in-Nano Therapeutics: Assessment on 3D Head and Neck Squamous Cell Carcinomas

Cancers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1063 ◽  
Author(s):  
Melissa Santi ◽  
Ana Katrina Mapanao ◽  
Domenico Cassano ◽  
Ylea Vlamidis ◽  
Valentina Cappello ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Poor Prognosis ◽  
Noble Metals ◽  
Patient Survival ◽  
3D Models ◽  
Squamous Cell Carcinomas ◽  
Metastasis Formation ◽  
Therapeutic Evaluation ◽  
Patient Survival Rate

Negative or positive HPV-associated Head and Neck Squamous Cell Carcinomas (HNSCCs) are high recurrence neoplasms usually resulting in a poor prognosis, mainly due to metastasis formation. Despite the low overall patient survival rate and the severe side effects, the treatment of choice is still cisplatin-based chemotherapy. Here, we report a straightforward protocol for the production of high throughput 3D models of negative or positive HPV-associated HNSCCs, together with their employment in the therapeutic evaluation of gold ultrasmall-in-nano architectures comprising an endogenously-activatable cisplatin prodrug. Beyond enhancing the biosafety of cisplatin, our approach paves the way for the establishment of synergistic co-therapies for HNSCCs based on excretable noble metals.

Loss of imprinting and loss of heterozygosity on 11p15.5 in head and neck squamous cell carcinomas

Head & Neck ◽  
2001 ◽  
Vol 23 (10) ◽  
pp. 851-859 ◽  
Author(s):  
Cl�udia A. Rainho ◽  
Luiz P. Kowalski ◽  
Silvia R. Rogatto
Keyword(s):  
Head And Neck ◽  
Loss Of Heterozygosity ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Loss Of Imprinting

scholarly journals Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas

Oncotarget ◽  
2011 ◽  
Vol 2 (12) ◽  
pp. 1165-1175 ◽  
Author(s):  
Daniela Gasparotto ◽  
Jerry Polesel ◽  
Alessandra Marzotto ◽  
Roberta Colladel ◽  
Sara Piccinin ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Poor Prognosis ◽  
Squamous Cell Carcinomas

Adjuvant chemo- and radiotherapy for poor prognosis head and neck squamous cell carcinomas

2005 ◽  
Vol 56 (3) ◽  
pp. 353-364 ◽  
Author(s):  
Jacques Bernier ◽  
David G. Pfister ◽  
Jay S. Cooper
Keyword(s):  
Head And Neck ◽  
Squamous Cell ◽  
Poor Prognosis ◽  
Squamous Cell Carcinomas
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