Pediatric visceral leishmaniasis: a retrospective study to propose the diagnostic tests algorithm in southern Iran

Author(s):  
Zahra Rezaei ◽  
Bahman Pourabbas ◽  
Sadaf Asaei ◽  
Vera Kühne ◽  
Shima Sepehrpour ◽  
...  
Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1163
Author(s):  
Fien Vanroye ◽  
Dorien Van den Bossche ◽  
Isabel Brosius ◽  
Bieke Tack ◽  
Marjan Van Esbroeck ◽  
...  

COVID-19 Antibody Detecting Rapid Diagnostic Tests (COVID-19 Ab RDTs) are the preferred tool for SARS-CoV-2 seroprevalence studies, particularly in low- and middle-income countries. The present study challenged COVID-19 Ab RDTs with pre-pandemic samples of patients exposed to tropical pathogens. A retrospective study was performed on archived serum (n = 94) and EDTA whole blood (n = 126) samples obtained during 2010–2018 from 196 travelers with malaria (n = 170), schistosomiasis (n = 25) and dengue (n = 25). COVID-19 Ab RDTs were selected based on regulatory approval status, independent evaluation results and detecting antigens. Among 13 COVID-19 Ab RDT products, overall cross-reactivity was 18.5%; cross-reactivity for malaria, schistosomiasis and dengue was 20.3%, 18.1% and 7.5%, respectively. Cross-reactivity for current and recent malaria, malaria antibodies, Plasmodium species and parasite densities was similar. Cross-reactivity among the different RDT products ranged from 2.7% to 48.9% (median value 14.5%). IgM represented 67.9% of cross-reactive test lines. Cross-reactivity was not associated with detecting antigens, patient categories or disease (sub)groups, except for schistosomiasis (two products with ≥60% cross-reactivity). The high cross-reactivity for malaria, schistosomiasis and—to a lesser extent—dengue calls for risk mitigation when using COVID-19 Ab RDTs in co-endemic regions.


Author(s):  
Luciana Silami Carvalho ◽  
Maria das Graças Braga ◽  
Dário Alves da Silva Costa ◽  
Taynãna César Simões ◽  
Mariana Dias Lula ◽  
...  

2013 ◽  
Vol 22 (3) ◽  
pp. 424-426 ◽  
Author(s):  
Monique Paiva de Campos ◽  
Denise Amaro da Silva ◽  
Maria de Fátima Madeira ◽  
Artur Augusto Mendes Velho Júnior ◽  
Fabiano Borges Figueiredo

In Brazil, American visceral leishmaniasis (AVL) is caused byLeishmania (Leishmania) chagasi and its main vector isLutzomyia longipalpis. Cases of canine visceral leishmaniasis (CVL) in non-endemic areas have been reported over the last few years throughout the country. The objective of this research note is to describe an autochthonous case of CVL that occurred in the municipality of Volta Redonda, state of Rio de Janeiro, an area where the disease is not endemic, alerting veterinarians and the scientific community to the expansion of this important zoonosis and advising veterinary practitioners on how to deal with a suspicion of CVL. Canine visceral leishmaniasis can be misdiagnosed within a broad spectrum of canine diseases based on clinical and laboratory findings. Therefore, knowledge of its clinical manifestations, specific and sensitive laboratory diagnostic tests and parasitological procedures are of the utmost importance for rapid confirmation and notification of a case, thus contributing directly to the control of a focus.


2018 ◽  
Vol 49 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Manijeh Nourian ◽  
Aliehsan Heidari ◽  
Saleheh Tajali ◽  
Erfan Ghasemi ◽  
Mehdi Mohebali ◽  
...  

Visceral leishmaniasis (VL) is a neglected disease. Our retrospective study describes 38 clinical and epidemiological characteristics of VL in patients admitted to a paediatric hospital in Tehran, Iran, who came from different geographical regions, indicating that the disease has spread to most parts of the country. Some 76.3% of the children documented suffered with symptoms of the disease for two months before admission.


Author(s):  
Marleen Boelaert ◽  
Francois Chappuis ◽  
Joris Menten ◽  
Johan van Griensven ◽  
Temmy Sunyoto ◽  
...  

AIDS Care ◽  
2021 ◽  
pp. 1-9
Author(s):  
Zahra Gheibi ◽  
Hassan Joulaei ◽  
Mohammad Fararouei ◽  
Mostafa Shokoohi ◽  
Zohre Foroozanfar ◽  
...  

2019 ◽  
pp. 170-180
Author(s):  
Marleen Boelaert ◽  
Suman Rijal ◽  
François Chappuis

2012 ◽  
Vol 55 (10) ◽  
pp. 1312-1319 ◽  
Author(s):  
Jane Cunningham ◽  
Epco Hasker ◽  
Pradeep Das ◽  
Sayda El Safi ◽  
Hiro Goto ◽  
...  

2007 ◽  
Vol 5 (S11) ◽  
pp. S31-S39 ◽  
Author(s):  
Marleen Boelaert ◽  
Sujit Bhattacharya ◽  
François Chappuis ◽  
Sayda H. El Safi ◽  
Asrat Hailu ◽  
...  

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