Genome-wide linkage analysis assessing parent-of-origin effects in the inheritance of birth weight

2002 ◽  
Vol 110 (5) ◽  
pp. 503-509 ◽  
Author(s):  
Robert S. Lindsay ◽  
Sayuko Kobes ◽  
William C. Knowler ◽  
Robert L. Hanson
Keyword(s):  
Birth Weight ◽  
Linkage Analysis ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Genome-Wide Linkage Analysis Assessing Parent-of-Origin Effects in the Inheritance of Type 2 Diabetes and BMI in Pima Indians

Diabetes ◽  
2001 ◽  
Vol 50 (12) ◽  
pp. 2850-2857 ◽  
Author(s):  
R. S. Lindsay ◽  
S. Kobes ◽  
W. C. Knowler ◽  
P. H. Bennett ◽  
R. L. Hanson
Keyword(s):  
Type 2 Diabetes ◽  
Linkage Analysis ◽  
Pima Indians ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Parent-Of-Origin Effects in Autism Identified through Genome-Wide Linkage Analysis of 16,000 SNPs

PLoS ONE ◽  
2010 ◽  
Vol 5 (9) ◽  
pp. e12513 ◽  
Author(s):  
Delphine Fradin ◽  
Keely Cheslack-Postava ◽  
Christine Ladd-Acosta ◽  
Craig Newschaffer ◽  
Aravinda Chakravarti ◽  
...  
Keyword(s):  
Linkage Analysis ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Genome-wide random regression analysis for parent-of-origin effects of body composition allometries in mouse

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Jingli Zhao ◽  
Shuling Li ◽  
Lijuan Wang ◽  
Li Jiang ◽  
Runqing Yang ◽  
...  
Keyword(s):  
Body Composition ◽  
Regression Analysis ◽  
Random Regression ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts

2012 ◽  
Vol 158A (4) ◽  
pp. 784-794 ◽  
Author(s):  
Min Shi ◽  
Jeffrey C. Murray ◽  
Mary L. Marazita ◽  
Ronald G. Munger ◽  
Ingo Ruczinski ◽  
...  
Keyword(s):  
Orofacial Clefts ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects ◽  
Genome Wide Study

scholarly journals Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

2018 ◽  
Vol 27 (16) ◽  
pp. 2927-2939 ◽  
Author(s):  
Gabriel Cuellar Partida ◽  
Charles Laurin ◽  
Susan M Ring ◽  
Tom R Gaunt ◽  
Allan F McRae ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects ◽  
Genome Wide Survey

scholarly journals Assessment of Parent-of-Origin Effects in Linkage Analysis of Quantitative Traits

2001 ◽  
Vol 68 (4) ◽  
pp. 951-962 ◽  
Author(s):  
Robert L. Hanson ◽  
Sayuko Kobes ◽  
Robert S. Lindsay ◽  
William C. Knowler
Keyword(s):  
Linkage Analysis ◽  
Quantitative Traits ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals CmCGG Methylation-Independent Parent-of-Origin Effects on Genome-Wide Transcript Levels in Isogenic Reciprocal F1 Triploid Plants

DNA Research ◽  
2013 ◽  
Vol 21 (2) ◽  
pp. 141-151 ◽  
Author(s):  
M. T. A. Donoghue ◽  
A. Fort ◽  
R. Clifton ◽  
X. Zhang ◽  
P. C. McKeown ◽  
...  
Keyword(s):  
Transcript Levels ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects

scholarly journals A statistical test for detecting parent-of-origin effects when parental information is missing

2017 ◽  
Vol 16 (4) ◽  
Author(s):  
Chiara Sacco ◽  
Cinzia Viroli ◽  
Mario Falchi
Keyword(s):  
Study Data ◽  
Epigenetic Mechanism ◽  
Parental Origin ◽  
Reference Allele ◽  
Parental Effect ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Related Individuals ◽  
Origin Effects ◽  
Parental Information

AbstractGenomic imprinting is an epigenetic mechanism that leads to differential contributions of maternal and paternal alleles to offspring gene expression in a parent-of-origin manner. We propose a novel test for detecting the parent-of-origin effects (POEs) in genome wide genotype data from related individuals (twins) when the parental origin cannot be inferred. The proposed method exploits a finite mixture of linear mixed models: the key idea is that in the case of POEs the population can be clustered in two different groups in which the reference allele is inherited by a different parent. A further advantage of this approach is the possibility to obtain an estimation of parental effect when the parental information is missing. We will also show that the approach is flexible enough to be applicable to the general scenario of independent data. The performance of the proposed test is evaluated through a wide simulation study. The method is finally applied to known imprinted genes of the MuTHER twin study data.

scholarly journals A powerful genome-wide feasible approach to detect parent-of-origin effects in studies of quantitative traits

2009 ◽  
Vol 18 (3) ◽  
pp. 379-384 ◽  
Author(s):  
Nadezhda M Belonogova ◽  
Tatiana I Axenovich ◽  
Yurii S Aulchenko
Keyword(s):  
Quantitative Traits ◽  
Genome Wide ◽  
Parent Of Origin ◽  
Origin Effects
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