Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol

2013 ◽  
Vol 36 (9) ◽  
pp. 1319-1326 ◽  
Author(s):  
Lian Hua Luo ◽  
Jeong-Woo Seo ◽  
Sun-Yeon Heo ◽  
Baek-Rock Oh ◽  
Dae-Hyuk Kim ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Aldehyde Dehydrogenases ◽  
Hydroxypropionic Acid ◽  
Identification And Characterization

scholarly journals Identification and characterization of acetyltransferase-type toxin-antitoxin locus in Klebsiella pneumoniae

2018 ◽  
Vol 108 (4) ◽  
pp. 336-349 ◽  
Author(s):  
Hongliang Qian ◽  
Qingqing Yao ◽  
Cui Tai ◽  
Zixin Deng ◽  
Jianhua Gan ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Identification And Characterization

Identification and Characterization of a Putative Dihydroorotase, KPN01074, from Klebsiella pneumoniae

2010 ◽  
Vol 29 (6) ◽  
pp. 445-452 ◽  
Author(s):  
Chuan-Cheng Wang ◽  
Huai-Wen Tsau ◽  
Wei-Ti Chen ◽  
Cheng-Yang Huang
Keyword(s):  
Klebsiella Pneumoniae ◽  
Identification And Characterization

scholarly journals Identification and Characterization of NDM-1-producing Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae in China

2019 ◽  
Vol 39 (2) ◽  
pp. 167-175 ◽  
Author(s):  
Zhou Liu ◽  
Yi Gu ◽  
Xin Li ◽  
Yanyan Liu ◽  
Ying Ye ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Identification And Characterization

Identification and characterization of Th cell epitopes in MrkD adhesin of Klebsiella pneumoniae

2010 ◽  
Vol 49 (1-2) ◽  
pp. 8-13 ◽  
Author(s):  
Yang Li ◽  
Zhi-jie Li ◽  
Wen-yu Han ◽  
Lian-cheng Lei ◽  
Chang-jiang Sun ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Th Cell ◽  
Identification And Characterization

scholarly journals Identification and Characterization of a New Porin Gene of Klebsiella pneumoniae: Its Role in β-Lactam Antibiotic Resistance

1999 ◽  
Vol 181 (9) ◽  
pp. 2726-2732 ◽  
Author(s):  
Antonio Doménech-Sánchez ◽  
Santiago Hernández-Allés ◽  
Luis Martínez-Martínez ◽  
Vicente J. Benedí ◽  
Sebastián Albertí
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Blot Analysis ◽  
Southern Blot Analysis ◽  
Functional Characterization ◽  
Standard Laboratory ◽  
Lactam Antibiotic ◽  
Resistant Strains ◽  
Identification And Characterization

ABSTRACT Klebsiella pneumoniae porin genes were analyzed to detect mutations accounting for the porin deficiency observed in many β-lactam-resistant strains. PCR and Southern blot analysis revealed the existence of a third porin gene in addition to the OmpK36 and OmpK35 porin genes previously described. This new porin gene was designated ompK37 and is present in all of the clinical isolates tested. The OmpK37 porin gene was cloned, sequenced, and overexpressed in Escherichia coli. In contrast to that of the major porins, OmpK37 porin expression was only detectable by Western blot analysis in porin-deficient β-lactam-resistant strains, suggesting strong down regulation under standard laboratory conditions. Functional characterization suggested a narrower pore for the OmpK37 porin than for K. pneumoniae porins OmpK36 and OmpK35. This correlated with the susceptibility to certain β-lactam antibiotics, since a K. pneumoniae strain expressing porin OmpK37, but not porin OmpK36 or OmpK35, was less susceptible to β-lactam antibiotics than the same strain expressing either porin OmpK36 or OmpK35.

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