High-efficient production of citric acid by Aspergillus niger from high concentration of substrate based on the staged-addition glucoamylase strategy

2017 ◽  
Vol 40 (6) ◽  
pp. 891-899 ◽  
Author(s):  
Baoshi Wang ◽  
Hua Li ◽  
Linghuan Zhu ◽  
Fengling Tan ◽  
Youran Li ◽  
...  
Keyword(s):  
Citric Acid ◽  
Aspergillus Niger ◽  
Efficient Production ◽  
High Concentration ◽  
High Efficient

Efficient production of citric acid in segmented fermentation using Aspergillus niger based on recycling of a pellet-dispersion strategy

RSC Advances ◽  
2016 ◽  
Vol 6 (107) ◽  
pp. 105003-105009
Author(s):  
Baoshi Wang ◽  
Jian Chen ◽  
Hua Li ◽  
Fuxin Sun ◽  
Youran Li ◽  
...  
Keyword(s):  
Citric Acid ◽  
Aspergillus Niger ◽  
Batch Fermentation ◽  
Fermentation Process ◽  
Efficient Production

Segmentation recycling fermentation based on a pellet-dispersion strategy to reconstruct the traditional citric acid batch fermentation process is reported.

scholarly journals High-Efficient Production of Adipose-Derived Stem Cell (ADSC) Secretome Through Maturation Process and Its Non-scarring Wound Healing Applications

2021 ◽  
Vol 9 ◽  
Author(s):  
Young-Hyeon An ◽  
Dae Hyun Kim ◽  
Eun Jung Lee ◽  
Dabin Lee ◽  
Mihn Jeong Park ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Tissue Repair ◽  
High Dose ◽  
Efficient Production ◽  
Skin Defect ◽  
High Concentration ◽  
Tissue Repair And Regeneration ◽  
High Efficient ◽  
Related Proteins

Recently, the stem cell-derived secretome, which is the set of proteins expressed by stem cells and secreted into the extracellular space, has been demonstrated as a critical contributor for tissue repair. In this study, we have produced two sets of high concentration secretomes from adipose-derived mesenchymal stem cells (ADSCs) that contain bovine serum or free of exogenous molecules. Through proteomic analysis, we elucidated that proteins related to extracellular matrix organization and growth factor-related proteins are highly secreted by ADSCs. Additionally, the application of ADSC secretome to full skin defect showed accelerated wound closure, enhanced angiogenic response, and complete regeneration of epithelial gaps. Furthermore, the ADSC secretome was capable of reducing scar formation. Finally, we show high-dose injection of ADSC secretome via intraperitoneal or transdermal delivery demonstrated no detectable pathological conditions in various tissues/organs, which supports the notion that ADSC secretome can be safely utilized for tissue repair and regeneration.

scholarly journals The Effect of Lipids on Citric Acid Production by an Aspergillus niger Mutant

1963 ◽  
Vol 30 (3) ◽  
pp. 365-379 ◽  
Author(s):  
N. F. MILLIS ◽  
B. H. TRUMPY ◽  
B. M. PALMER
Keyword(s):  
Citric Acid ◽  
Aspergillus Niger ◽  
Acid Production ◽  
Citric Acid Production
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