Open versus minimally invasive liver surgery for colorectal liver metastases (LapOpHuva): a prospective randomized controlled trial

2019 ◽  
Vol 33 (12) ◽  
pp. 3926-3936 ◽  
Author(s):  
Ricardo Robles-Campos ◽  
Víctor Lopez-Lopez ◽  
Roberto Brusadin ◽  
Asunción Lopez-Conesa ◽  
Pedro José Gil-Vazquez ◽  
...  
Trials ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Åsmund Avdem Fretland ◽  
Airazat M Kazaryan ◽  
Bjørn Atle Bjørnbeth ◽  
Kjersti Flatmark ◽  
Marit Helen Andersen ◽  
...  

Author(s):  
Andrea Ruzzenente ◽  
◽  
Andrea Ciangherotti ◽  
Luca Aldrighetti ◽  
Giuseppe Maria Ettorre ◽  
...  

Abstract Background Although isolated caudate lobe (CL) liver resection is not a contraindication for minimally invasive liver surgery (MILS), feasibility and safety of the procedure are still poorly investigated. To address this gap, we evaluate data on the Italian prospective maintained database on laparoscopic liver surgery (IgoMILS) and compare outcomes between MILS and open group. Methods Perioperative data of patients with malignancies, as colorectal liver metastases (CRLM), hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), non-colorectal liver metastases (NCRLM) and benign liver disease, were retrospectively analyzed. A propensity score matching (PSM) analysis was performed to balance the potential selection bias for MILS and open group. Results A total of 224 patients were included in the study, 47 and 177 patients underwent MILS and open isolated CL resection, respectively. The overall complication rate was comparable between the two groups; however, severe complication rate (Dindo–Clavien grade ≥ 3) was lower in the MILS group (0% versus 6.8%, P = ns). In-hospital mortality was 0% in both groups and mean hospital stay was significantly shorter in the MILS group (P = 0.01). After selection of 42 MILS and 43 open CL resections by PSM analysis, intraoperative and postoperative outcomes remained similar except for the hospital stay which was not significantly shorter in MILS group. Conclusions This multi-institutional cohort study shows that MILS CL resection is feasible and safe. The surgical procedure can be technically demanding compared to open resection, whereas good perioperative outcomes can be achieved in highly selected patients.


2015 ◽  
Vol 40 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Satit Thiengwittayaporn ◽  
Yupadee Fusakul ◽  
Nunnapat Kangkano ◽  
Chanintorn Jarupongprapa ◽  
Narattaphol Charoenphandhu

Trials ◽  
2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Jennifer Straatman ◽  
Nicole van der Wielen ◽  
Miguel A Cuesta ◽  
Suzanne S Gisbertz ◽  
Koen J Hartemink ◽  
...  

2018 ◽  
Vol 268 (6) ◽  
pp. e69 ◽  
Author(s):  
Anthony K. C. Chan ◽  
Saurabh Jamdar ◽  
Aali J. Sheen ◽  
Ajith K. Siriwardena

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