Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up

2020 ◽  
Author(s):  
Ehsan Sediqi ◽  
Alexandros Tsoposidis ◽  
Ville Wallenius ◽  
Hans Axelsson ◽  
Jan Persson ◽  
...  
Keyword(s):  
Heller Myotomy ◽  
Randomized Study ◽  
Laparoscopic Heller Myotomy ◽  
Pneumatic Dilatation ◽  
Prospective Randomized Study

1374: A Two Years Follow-Up, Prospective Randomized Study on Cystocele Repair with or without Pelvicol Implant

2007 ◽  
Vol 177 (4S) ◽  
pp. 453-453 ◽  
Author(s):  
Ervin Kocjancic ◽  
Simone Crivellaro ◽  
Fabio Bernasconi ◽  
Fabio Magatti ◽  
Bruno Frea ◽  
...  
Keyword(s):  
Randomized Study ◽  
Prospective Randomized Study

A prospective randomized study of follow-up after radical surgery for colorectal cancer

1997 ◽  
Vol 84 (5) ◽  
pp. 666-669 ◽  
Author(s):  
B. J. Kjeldsen ◽  
O. Kronborg ◽  
C. Fenger ◽  
O. D. Jørgensen
Keyword(s):  
Colorectal Cancer ◽  
Radical Surgery ◽  
Randomized Study ◽  
Prospective Randomized Study

A prospective randomized study comparing MRI-based and standard pathway for prostate cancer diagnosis: Three years follow up

2018 ◽  
Vol 17 (8) ◽  
pp. 176-177
Author(s):  
M. Manfredi ◽  
C. Fiori ◽  
I. Morra ◽  
M. Cossu ◽  
S. De Luca ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Diagnosis ◽  
Randomized Study ◽  
Prospective Randomized Study ◽  
Prostate Cancer Diagnosis

scholarly journals Standard-dose versus high-dose radiotherapy with concurrent chemotherapy in esophageal cancer: A prospective randomized study

2018 ◽  
Vol 07 (01) ◽  
pp. 27-30 ◽  
Author(s):  
Navin Nayan ◽  
M. Bhattacharyya ◽  
Vikas K. Jagtap ◽  
A. K. Kalita ◽  
R. Sunku ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Total Dose ◽  
Standard Dose ◽  
Randomized Study ◽  
Complete Response ◽  
Concurrent Chemotherapy ◽  
Prospective Randomized Study ◽  
High Dose ◽  
Large Sample Size

Abstract Objective: The objective of this study is comparision of local and distant control rates with high-dose versus standard-dose radiotherapy along with concurrent chemotherapy in esophageal cancer – a prospective randomized study. Materials and Methods: Histologically proven Stage I–III patients with carcinoma esophagus were randomized into two groups. One group has been treated with standard-dose radiotherapy, i.e., a total dose of 50.4 Gy (1.8 Gy/day, 28#, 5 days/week). The other group (study arm) has received high-dose radiotherapy, i.e. a total dose of 64.8 Gy (1.8 Gy/day, 36#, 5 days/week). Both groups have received 2 cycles of 3 weekly concurrent chemotherapy (cisplatin 75 mg/m[2] on day 1 and 5-fluorouracil 750 mg/m[2] continuous intravenous infusion over 24 h on day 1–4). Follow-up response evaluation was done by both endoscopy and computed tomography scan after 6–8 weeks and after 2 months thereafter. Results: Out of a total of 28 patients, 68% showed a complete response, 14% showed partial response, and 18% patients developed progressive disease at first and subsequent follow up (median follow-up of 21 months). Among the complete response patients, rates were higher in high-dose group compared to standard-dose radiotherapy group (71% vs. 64%, P = 0.38). Treatment-related toxicities were acceptable in both groups. Conclusion: High-dose radiotherapy with concurrent chemotherapy seems to be more effective with acceptable toxicity in our study. However, further follow-up and large sample size may be required to validate the current study conclusion.

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