Long-term outcomes of patients with recurrent squamous cell carcinoma of the esophagus undergoing salvage endoscopic resection after definitive chemoradiotherapy

2020 ◽  
Author(s):  
Mai Ego ◽  
Seiichiro Abe ◽  
Yukihiro Nakatani ◽  
Satoru Nonaka ◽  
Haruhisa Suzuki ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Long Term Outcomes ◽  
Definitive Chemoradiotherapy ◽  
Carcinoma Of The Esophagus ◽  
Recurrent Squamous Cell Carcinoma

Long-term outcome of endoscopic resection for intramucosal esophageal squamous cell cancer: a secondary analysis of the Japan Esophageal Cohort study

Endoscopy ◽  
2020 ◽  
Vol 52 (11) ◽  
pp. 967-975 ◽  
Author(s):  
Ichiro Oda ◽  
Yuichi Shimizu ◽  
Toshiyuki Yoshio ◽  
Chikatoshi Katada ◽  
Tetsuji Yokoyama ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Cumulative Incidence ◽  
Survival Rates ◽  
Secondary Analysis ◽  
Muscularis Mucosa ◽  
Long Term Outcomes

Background Prospectively collected long-term data of patients undergoing endoscopic resection for superficial esophageal squamous cell carcinoma (ESCC) are limited. The aim of this study was to determine the prospectively collected long-term outcomes of endoscopic resection for ESCC as a secondary analysis of the Japan Esophageal Cohort (JEC) study. Methods Patients who underwent endoscopic resection of intramucosal ESCC at 16 institutions between September 2005 and May 2010 were enrolled in the JEC study. All patients underwent endoscopic examination with iodine staining at 3 and 6 months after resection, and every 6 months thereafter. We investigated clinical courses after endoscopic resection, survival rates, and cumulative incidence of metachronous ESCC. Results 330 patients (mean age 67.0 years) with 396 lesions (mean size 20.4 mm) were included in the analysis. Lesions were diagnosed as high-grade intraepithelial neoplasia in 17.4 % and as squamous cell carcinoma in 82.6 % (limited to epithelium in 28.4 %, to lamina propria in 55.4 %, and to muscularis mucosa in 16.2 %). En bloc resection was achieved in 291 (73.5 %). The median follow-up period was 49.4 months. Local recurrences occurred in 13 patients (3.9 %) and were treated by endoscopic procedures. Lymph node metastasis occurred in two patients (0.6 %) after endoscopic resection. The 5-year overall, disease-specific, and metastasis-free survival rates were 95.1 %, 99.1 %, and 94.6 %, respectively. The 5-year cumulative incidence rate of metachronous ESCC was 25.7 %. Conclusions Our study demonstrated that endoscopic resection is an effective treatment for intramucosal ESCC, with favorable long-term outcomes.

T1 Squamous Cell Carcinoma of the Esophagus: Long-Term Outcomes and Prognostic Factors After Esophagectomy

2013 ◽  
Vol 21 (3) ◽  
pp. 932-938 ◽  
Author(s):  
Toshiaki Tanaka ◽  
Satoru Matono ◽  
Naoki Mori ◽  
Kazuo Shirouzu ◽  
Hiromasa Fujita
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prognostic Factors ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Long Term Outcomes ◽  
Carcinoma Of The Esophagus

Comparison of the Long-Term Outcomes of Endoscopic Resection for Superficial Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus in Japan

2014 ◽  
Vol 109 (3) ◽  
pp. 348-356 ◽  
Author(s):  
Kenichiro Nakagawa ◽  
Tomoyuki Koike ◽  
Katsunori Iijima ◽  
Hirohiko Shinkai ◽  
Waku Hatta ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Long Term Outcomes ◽  
Adenocarcinoma Of The Esophagus

Sa1246 LONG-TERM OUTCOMES IN THE PATIENTS WITH PT1A-MM/T1B-SM1 ESOPHAGEAL SQUAMOUS CELL CARCINOMA PRECEDING ENDOSCOPIC RESECTION

2019 ◽  
Vol 89 (6) ◽  
pp. AB186
Author(s):  
Yuko Hara ◽  
Akira Dobashi ◽  
Akio Koizumi ◽  
Hiroto Furuhashi ◽  
Hiroaki Matsui ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Long Term Outcomes

Long-term outcomes of combined endoscopic resection and chemoradiotherapy for esophageal squamous cell carcinoma with submucosal invasion

2018 ◽  
Vol 50 (8) ◽  
pp. 833-838 ◽  
Author(s):  
Shoichi Yoshimizu ◽  
Toshiyuki Yoshio ◽  
Akiyoshi Ishiyama ◽  
Tomohiro Tsuchida ◽  
Yusuke Horiuchi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Submucosal Invasion ◽  
Long Term Outcomes
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