A broad clinical spectrum of PLCε1-related kidney disease and intrafamilial variability

2022 ◽  
Author(s):  
Esra Karabağ Yılmaz ◽  
Seha Saygili ◽  
Bora Gulhan ◽  
Nur Canpolat ◽  
Aysun Karabay Bayazıt ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Clinical Spectrum ◽  
Intrafamilial Variability

scholarly journals Clinical spectrum, prognosis and estimated prevalence of DNAJB11-kidney disease

2020 ◽  
Vol 98 (2) ◽  
pp. 476-487 ◽  
Author(s):  
Vinh T. Huynh ◽  
Marie-Pierre Audrézet ◽  
John A. Sayer ◽  
Albert C. Ong ◽  
Siriane Lefevre ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Clinical Spectrum

Cardiovascular Disease in Patients with Kidney Disease

2012 ◽  
Author(s):  
Ernest I Mandel ◽  
David M. Charytan
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
Bleeding Risk ◽  
Arterial Disease ◽  
The United States ◽  
Clinical Spectrum ◽  
Stage Renal Disease ◽  
End Stage

Cardiovascular disease (CVD) is prevalent in patients with chronic kidney disease (CKD) and is the leading cause of morbidity and mortality in dialysis patients. Clinical practice guidelines established by the National Kidney Foundation identify five stages of CKD defined by estimated glomerular filtration rate (eGFR) as determined by the abbreviated Modification of Diet in Renal Disease (MDRD) study equation. The National Health and Nutrition Epidemiology Survey (NHANES III) estimated that 13% of adults in the United States have CKD. An estimated 5 to 10% of the world's population—a staggering 300 to 600 million people—have CKD. This chapter covers the epidemiology, clinical spectrum, pathogenesis, and management of CVD in patients who have CKD. The clinical spectrum of CVD in patients with CKD is divided into four major categories: arterial disease, myocardial disease, disorders of cardiac rhythm, and valvular disease. Sections discuss some or all of the following: epidemiology/pathophysiology, diagnosis, management, risk factors, intervention, prevention. The chapter includes 4 tables and 6 figures. Figures present age-standardized rates of death, Kaplan–Meier estimates of rates of death, mortality by stage of CKD, hazard ratios and 95% confidence intervals for all-cause and cardiovascular mortality, cardio-renal syndrome pathophysiology, and ratios for actual to expected number of occurrences of sudden death. Tables list the five stages of CKD, types of CVD associated with CKD, risk factors for CVD in patients with CKD/end-stage renal disease (ESRD), and factors contributing to platelet dysfunction and enhanced bleeding risk in CKD/ESRD. This chapter contains 191 references.

The Clinical Spectrum of Anaphylaxis in North-West England

1996 ◽  
Vol 26 (12) ◽  
pp. 1364-1370 ◽  
Author(s):  
R. S. H. Pumphrey ◽  
S. J. Stanworth
Keyword(s):  
Clinical Spectrum ◽  
North West
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