Expression of Ki-67 antigen using monoclonal antibody MIB-1 in children with post-streptococcal glomerulonephritis

2000 ◽  
Vol 14 (5) ◽  
pp. 389-392 ◽  
Author(s):  
W. Y. Chung ◽  
Y. J. Kim
1995 ◽  
Vol 177 (4) ◽  
pp. 375-377 ◽  
Author(s):  
YASUO YAMADA ◽  
HIDEMI YAMAUCHI ◽  
KENJI KAKIZAKI ◽  
HIROYOSHI SUZUKI

1998 ◽  
Vol 27 (4) ◽  
pp. 251-256 ◽  
Author(s):  
C. Laprie ◽  
J. Abadie ◽  
M. F. Amardeilh ◽  
I. Raymond ◽  
M. Delverdier

2003 ◽  
Vol 61 (3A) ◽  
pp. 547-551 ◽  
Author(s):  
Antonio Fernandes Ferrari ◽  
Maria Betânia Mahler Araújo ◽  
Paulo Henrique Aguiar ◽  
José Pindaro Pereira Plese

In the past few years, the monoclonal antibody MIB-1 has been used by researchers in order to retrospectively study paraffin imbibed tumor fragments. The medulloblastoma is the most common malignant central nervous system tumor in childhood. The objectives were: determination of the mean Mib-1 LI value from these patients, as well as the prognostic value of the method.This retrospective study represents an analysis of the cellular proliferation index of posterior fossa medulloblastomas collected from 22 patients at A.C. Camargo Hospital, from January 1990 to December 1999. The histopathological diagnosis was confirmed by H&E and proliferative index (LI) was achived with Mib-1 which detects proliferating cells during G1, G2, S and M phases.The results demostrated that the mean Mib-1 was 30,1%, and ranged from 5,2% to 62,0%.In conclusion, this method has prognostic value, has to be used as routine for patients harboring medulloblastomas and the ones who have PI greater than the mean value found in this study, should be treated aggressively.


1995 ◽  
Vol 134 (1-2) ◽  
pp. 35-39 ◽  
Author(s):  
P. H. Aguiar ◽  
M. Tatagiba ◽  
E. Dankoweit-Timpe ◽  
C. Matthies ◽  
M. Samii ◽  
...  

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