Measuring health-related quality of life and neutropenia-specific concerns among older adults undergoing chemotherapy: validation of the Functional Assessment of Cancer Therapy–Neutropenia (FACT-N)

2007 ◽  
Vol 16 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Lynne I. Wagner ◽  
Jennifer L. Beaumont ◽  
Beiying Ding ◽  
Jennifer Malin ◽  
Amy Peterman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Cancer Therapy ◽  
Functional Assessment ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals HEALTH-RELATED QUALITY OF LIFE (HRQoL) ASSESSMENT FOLLOWING RADICAL CYSTECTOMY IN POPULATION OF A SOUTH ASIAN COUNTRY

2018 ◽  
Vol 4 (3) ◽  
Author(s):  
Nasira Hayat ◽  
Suhaib Bin Bilal Hafi ◽  
Farhana Badar ◽  
Irfan Ahmed
Keyword(s):  
Quality Of Life ◽  
Cancer Therapy ◽  
Radical Cystectomy ◽  
South Asian ◽  
Functional Assessment ◽  
Well Being ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Purpose: Radical cystectomy is carried out for muscle invasive bladder (BL) cancer, which greatly affects the quality of life. The objective of our study was to assess the health-related quality of life (HRQoL) in patients following radicalcystectomy.Methods: A retrospective review was done in patients that underwent radical cystectomy between July 2009 and November 2014 at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan. HRQoLassessments of 34 patients done during clinical psychology review were included in this study. HRQoL was assessed using functional assessment of cancer therapy-BL questionnaire.Results: Low scores were observed in physical well-being and emotional well-being domains with mean scores of 7.32 and 7.97, respectively. Patients scored high on social and family well-being, functional well-being and additionalconcerns, with mean scores of 24.9, 17.24 and 21.73, respectively.Conclusions: Psychological evaluation and rehabilitation should be an integral part of surveillance after radical cystectomy.Key words: Bladder cancer, functional assessment of cancer therapy-bladder, health-related quality of life, radicalcystectomy, South Asian

Measuring Health-Related Quality of Life in Patients With Hepatobiliary Cancers: The Functional Assessment of Cancer Therapy–Hepatobiliary Questionnaire

2002 ◽  
Vol 20 (9) ◽  
pp. 2229-2239 ◽  
Author(s):  
Nancy Heffernan ◽  
David Cella ◽  
Kimberly Webster ◽  
Linda Odom ◽  
Mary Martone ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Therapy ◽  
Functional Assessment ◽  
Health Related Quality ◽  
Item Generation ◽  
Validity Testing ◽  
Related Quality ◽  
Health Related ◽  
Disease Specific

PURPOSE: This is the first report on the development and initial validation of the Functional Assessment of Cancer Therapy–Hepatobiliary (FACT-Hep) questionnaire, a 45-item self-report instrument designed to measure health-related quality of life (HRQL) in patients with hepatobiliary cancers. The FACT-Hep consists of the 27-item FACT-G, which assesses generic HRQL concerns, and the newly validated 18-item Hepatobiliary Subscale (HS), which assesses disease-specific issues. PATIENTS AND METHODS: The development of the HS followed a four-phase process of item generation, item reduction, scale construction, and reliability/validity testing. Two independent samples were studied: item generation (sample 1; n = 30) and reliability/validity testing (sample 2; n = 51). RESULTS: In sample 2, all subscales and aggregated scores showed high internal consistency at initial assessment (Cronbach’s alpha range, 0.72 to 0.94) and retesting (Cronbach’s alpha range, 0.81 to 0.94). Measurement stability over a 3- to 7-day period was also high for all aggregated scales (test-retest correlation range, 0.84 to 0.91; intraclass correlation coefficient range, 0.82 to 0.90). Convergent and divergent validity were demonstrated by examining relationships between FACT subscales and mood, social support, and social desirability. Finally, when performance status and treatment status were used to divide sample 2, the HS differentiated groups to a degree comparable to the Physical and Functional Well-Being subscales of the FACT-G, thereby contributing favorably to a 32-item Trial Outcome Index. In addition to the 18 validated, scored items in the HS, seven treatment-related items may be appended, if clinically indicated, as a separate subscale. CONCLUSION: The 45-item FACT-Hep can be used independently as a brief measure of disease-related symptoms and functioning. Alone or paired with the FACT-G, the HS has promise for use in assessing the disease-specific HRQL of patients with hepatobiliary cancers.

scholarly journals Evaluation of the health-related quality of life of hematopoietic stem cell transplantation patients

2011 ◽  
Vol 19 (6) ◽  
pp. 1322-1328 ◽  
Author(s):  
Carla Libralli Tostes dos Santos ◽  
Namie Okino Sawada ◽  
Jair Lício Ferreira dos Santos
Keyword(s):  
Quality Of Life ◽  
Cancer Therapy ◽  
Functional Assessment ◽  
Positive Impact ◽  
Demographic Data ◽  
Health Related Quality ◽  
Hematopoietic Stem ◽  
Related Quality ◽  
Health Related

This study evaluates the Health-Related Quality of Life of patients undergoing analogous and allogeneic transplantation at three different points in time: before, 30 and 180 days after transplantation, along with correlated clinical and socio-demographic data. Two questionnaires were used for data collection: the first addressed clinical and socio-demographic data and the second was the Functional Assessment Cancer Therapy translated and validated for Brazilian Portuguese. The initial sample was composed of 30 patients while 26 were ultimately evaluated at the three points. The set of results indicated a positive impact on Health-Related Quality of Life six months after transplantation. Despite the fact that there were additional concerns and some aspects such as physical and functional aspects were affected 30 days after the procedure, the Functional Assessment Cancer Therapy scores obtained six months after HSCT improved in all components, reaching levels above those prior to the procedure, especially physical and emotional aspects and the relationship with the physician.

scholarly journals Measuring Health-Related Quality of Life in Leukemia: The Functional Assessment of Cancer Therapy – Leukemia (FACT-Leu) Questionnaire

2012 ◽  
Vol 15 (8) ◽  
pp. 1051-1058 ◽  
Author(s):  
David Cella ◽  
Sally E. Jensen ◽  
Kimberly Webster ◽  
Du Hongyan ◽  
Jin-Shei Lai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Therapy ◽  
Functional Assessment ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Association between eHealth Literacy and Health-Related Quality of Life among Chinese Older Adults: A Cross-Sectional Study (Preprint)

2020 ◽  
Author(s):  
Shaojie Li ◽  
Yongtian Yin ◽  
Lijun Chen ◽  
Guanghui Cui ◽  
Jiaqin Li ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Mental Component Summary ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Chinese Older Adults ◽  
Ehealth Literacy ◽  
Related Quality ◽  
Health Related

BACKGROUND Older adults’ health literacy levels are crucial to improving health outcomes and health-related quality of life (HRQoL). However, the impact of eHealth literacy on HRQoL in older adults is unclear. OBJECTIVE The aim of this study was to examine the association between eHealth literacy and HRQoL of older adults and provide reference for the development of network intervention measures related to the health quality of life of the older adults. METHODS An anonymous cross-sectional survey was conducted among 1,201 adults aged 60 or older from Jinan, China. The eHealth Literacy Scale and Short-Form Health Survey (SF-12) were used to measure eHealth literacy and HRQoL. We used linear regression to test the adjusted association between eHealth literacy and HRQoL. RESULTS Most participants (88.9%) had inadequate eHealth literacy. Lower eHealth literacy was related to older age ( F=12.618, P<.001), female gender( t=3.303, P<.01), living in rural areas( F=11.356, P<.001), having less education( F=59.084, P<.001), being unmarried, divorced or widowed( t=4.416, P<.001), having a lower family income( F=38.017, P<.001), living with others(χ2=4.319, P<.05), and not having health insurance( F=12.713, P<.001). There were significant differences across physical functioning( t=-4.862, P<.001), role- physical( t=-2.485, P<.05), bodily pain( t=-3.470, P<.01), general health( t=-4.449, P<.001), vitality( t=-3.498, P<.001), role-emotional( t=-2.654, P<.01), mental health( t=-4.150, P<.001), physical component summary( t=-6.350, P<.001) and mental component summary( t=-4.483, P<.001) between adequate eHealth literacy and inadequate eHealth literacy. After controlling for age, gender, and other covariates, adequate eHealth literacy was positively related to physical component summary ( beta=7.6, P<.001) and mental component summary(beta=4.6, P=.001). CONCLUSIONS This study showed that Chinese older adults with higher eHealth literacy were more likely to contribute to higher HRQoL. Thus, Older adults’ eHealth literacy levels need to be taken into account when formulating health education and promotion programs for older adults, especially when the expected outcome is to improve HRQoL.

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