Lower serum uric acid is associated with mild cognitive impairment in early Parkinson’s disease: a 4-year follow-up study

2016 ◽  
Vol 123 (12) ◽  
pp. 1399-1402 ◽  
Author(s):  
Maria Teresa Pellecchia ◽  
Riccardo Savastano ◽  
Marcello Moccia ◽  
Marina Picillo ◽  
Pietro Siano ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Uric Acid ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Serum Uric Acid ◽  
Lower Serum ◽  
Follow Up Study ◽  
Early Parkinson’S Disease

Analyses of Visuospatial and Visuoperceptual Errors as Predictors of Dementia in Parkinson’s Disease Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

2020 ◽  
pp. 1-11
Author(s):  
Iván Galtier ◽  
Antonieta Nieto ◽  
María Mata ◽  
Jesús N. Lorenzo ◽  
José Barroso
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Poor Performance ◽  
Subjective Cognitive Decline ◽  
Independent Risk Factors

ABSTRACT Objective: Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) in Parkinson’s disease (PD) are considered as the risk factors for dementia (PDD). Posterior cortically based functions, such as visuospatial and visuoperceptual (VS-VP) processing, have been described as predictors of PDD. However, no investigations have focused on the qualitative analysis of the Judgment of Line Orientation Test (JLOT) and the Facial Recognition Test (FRT) in PD-SCD and PD-MCI. The aim of this work was to study the VS-VP errors in JLOT and FRT. Moreover, these variables are considered as predictors of PDD. Method: Forty-two PD patients and 19 controls were evaluated with a neuropsychological protocol. Patients were classified as PD-SCD and PD-MCI. Analyses of errors were conducted following the procedure described by Ska, Poissant, and Joanette (1990). Follow-up assessment was conducted to a mean of 7.5 years after the baseline. Results: PD-MCI patients showed a poor performance in JLOT and FRT total score and made a greater proportion of severe intraquadrant (QO2) and interquadrant errors (IQO). PD-SCD showed a poor performance in FRT and made mild errors in JLOT. PD-MCI and QO2/IQO errors were independent risk factors for PDD during the follow-up. Moreover, the combination of both PD-MCI diagnosis and QO2/IQO errors was associated with a greater risk. Conclusions: PD-MCI patients presented a greater alteration in VS-VP processing observable by the presence of severe misjudgments. PD-SCD patients also showed mild difficulties in VS-SP functions. Finally, QO2/IQO errors in PD-MCI are a useful predictor of PDD, more than PD-MCI diagnosis alone.

Gender differences in non-motor symptoms in early Parkinson's disease: A 2-years follow-up study on previously untreated patients

2014 ◽  
Vol 20 (8) ◽  
pp. 850-854 ◽  
Author(s):  
Marina Picillo ◽  
Roberto Erro ◽  
Marianna Amboni ◽  
Katia Longo ◽  
Carmine Vitale ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Gender Differences ◽  
Parkinson's Disease ◽  
Motor Symptoms ◽  
Follow Up Study ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

Serum uric acid level and its association with motor subtypes and non-motor symptoms in early Parkinson's disease: PALS study

2018 ◽  
Vol 55 ◽  
pp. 50-54 ◽  
Author(s):  
Xinxin Huang ◽  
Samuel Yong-Ern Ng ◽  
Nicole Shuang-Yu Chia ◽  
Sanchalika Acharyya ◽  
Fiona Setiawan ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Motor Symptoms ◽  
Non Motor Symptoms ◽  
Early Parkinson’S Disease

Transcranial magnetic stimulation follow-up study in early Parkinson's disease: A decline in compensation with disease progression?

2015 ◽  
Vol 30 (8) ◽  
pp. 1098-1106 ◽  
Author(s):  
Maja Kojovic ◽  
Panagiotis Kassavetis ◽  
Matteo Bologna ◽  
Isabel Pareés ◽  
Ignacio Rubio-Agusti ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Transcranial Magnetic Stimulation ◽  
Disease Progression ◽  
Magnetic Stimulation ◽  
Follow Up Study ◽  
Early Parkinson’S Disease

Striatal subregional 6-[18F]fluoro-L-dopa uptake in early Parkinson's disease: A two-year follow-up study

2006 ◽  
Vol 21 (7) ◽  
pp. 958-963 ◽  
Author(s):  
Anna Brück ◽  
Sargo Aalto ◽  
Elina Nurmi ◽  
Tero Vahlberg ◽  
Jörgen Bergman ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Follow Up Study ◽  
Early Parkinson’S Disease ◽  
Dopa Uptake

Cognitive impairment in patients with Parkinson’s disease: A 30-month follow-up study

2016 ◽  
Vol 151 ◽  
pp. 65-69 ◽  
Author(s):  
Ling Chen ◽  
Cuiyu Yu ◽  
Ning Zhang ◽  
Junjun Liu ◽  
Weiguo Liu
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Follow Up Study

scholarly journals Ventricular enlargement and mild cognitive impairment in early Parkinson's disease

2010 ◽  
Vol 26 (2) ◽  
pp. 297-301 ◽  
Author(s):  
Turi O. Dalaker ◽  
Robert Zivadinov ◽  
Deepa Preeti Ramasamy ◽  
Mona K. Beyer ◽  
Guido Alves ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Ventricular Enlargement ◽  
Early Parkinson’S Disease

scholarly journals Quality of Life and Mild Cognitive Impairment in Early Parkinson’s Disease: Does Subtype Matter?

2015 ◽  
Vol 4 (3) ◽  
pp. 331-336 ◽  
Author(s):  
Rachael A. Lawson ◽  
Alison J. Yarnall ◽  
Gordon W. Duncan ◽  
Tien K. Khoo ◽  
David P. Breen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Early Parkinson’S Disease
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