Molecular characterization and complete genome analysis of human enterovirus 71 and coxsackievirus A16 from children with hand, foot and mouth disease in Thailand during 2008-2011

2011 ◽  
Vol 156 (11) ◽  
pp. 2007-2013 ◽  
Author(s):  
Jiratchaya Puenpa ◽  
Apiradee Theamboonlers ◽  
Sumeth Korkong ◽  
Piyada Linsuwanon ◽  
Chittima Thongmee ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Genome Analysis ◽  
Complete Genome ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Coxsackievirus A16 ◽  
Human Enterovirus 71 ◽  
Complete Genome Analysis

scholarly journals Detection of human enterovirus 71 and coxsackievirus A16 in children with hand, foot and mouth disease in China

2012 ◽  
Vol 5 (4) ◽  
pp. 1001-1004 ◽  
Author(s):  
LING CHEN ◽  
XIAOZHOU MOU ◽  
QIONG ZHANG ◽  
YIFEI LI ◽  
JIAN LIN ◽  
...  
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Coxsackievirus A16 ◽  
Human Enterovirus 71 ◽  
Foot And Mouth

Detection of human enterovirus 71 and Coxsackievirus A16 in an outbreak of hand, foot, and mouth disease in Henan Province, China in 2009

Virus Genes ◽  
2012 ◽  
Vol 46 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Xingliang Fan ◽  
Jun Jiang ◽  
Yanjing Liu ◽  
Xueyong Huang ◽  
Pengzhi Wang ◽  
...  
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Henan Province ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Coxsackievirus A16 ◽  
Human Enterovirus 71 ◽  
Foot And Mouth

Complete genome analysis of enterovirus 71 isolated from an outbreak in Taiwan and rapid identification of enterovirus 71 and coxsackievirus A16 by RT-PCR

2001 ◽  
Vol 65 (2) ◽  
pp. 331-339 ◽  
Author(s):  
Jing-Jou Yan ◽  
Ih-Jen Su ◽  
Po-Fu Chen ◽  
Ching-Chuan Liu ◽  
Chun-Keung Yu ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Complete Genome ◽  
Enterovirus 71 ◽  
Rapid Identification ◽  
Rt Pcr ◽  
Coxsackievirus A16 ◽  
Complete Genome Analysis

scholarly journals Onychomadesis associated with hand, foot, and mouth disease: a prospective observational study from North Chennai

2020 ◽  
Vol 6 (3) ◽  
pp. 367
Author(s):  
Saraswathy Pichaachari ◽  
Jayanthi Nagappan Subramaniam ◽  
Sajeetha Sundaram
Keyword(s):  
Clinical Diagnosis ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Time Interval ◽  
Benign Condition ◽  
Human Enterovirus 71 ◽  
Foot And Mouth ◽  
Hands And Feet

<p class="abstract"><strong>Background:</strong> Hand, foot, and mouth disease (HFMD) is a common febrile illness caused by coxsackievirus A16 and human enterovirus 71 characterized by vesicular eruptions on hands and feet and enanthem on oral mucosa. Resolves usually without complications but onychomadesis can occur as a late sequlae sometimes.</p><p class="abstract"><strong>Methods:</strong> Children with clinical diagnosis of HFMD between April to June 2018 were included in the study. Age, sex, duration of illness, cutaneous features and nail changes were noted at initial visit and during every week for next 6 weeks.<strong></strong></p><p class="abstract"><strong>Results:</strong> 58 children were recruited in the study with boys to girl’s ratio 1.2:1. The average age was 5.3 years. The vesicular lesions predominantly involved palms and soles (88.3%). 65.5% had history of fever and pruritis was the commonest cutaneous symptom. 27 children (48.21%) developed onychomadesis during follow up with average time interval of 3.2 weeks between the clinical diagnosis and nail shedding. Reassurance about spontaneous resolution of the condition given to the parents.</p><p class="abstract"><strong>Conclusions:</strong> Our study strengthened the association between the HFMD and occurrence of onychomadesis. Physician’s awareness about this benign condition is needed to avoid parental anxiety, unnecessary investigations and treatment for the children.   </p>

scholarly journals Study the current scenario of hand foot mouth disease an Indian prospective

2020 ◽  
Vol 7 (7) ◽  
pp. 1558
Author(s):  
Ravi Sahota ◽  
Navpreet Kaur ◽  
Gurpal Singh ◽  
Nisha Upadhyay
Keyword(s):  
Communicable Disease ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Neurological Complications ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Cross Sectional ◽  
Timely Initiation ◽  
Human Enterovirus 71 ◽  
Hand Foot Mouth Disease

Background: The hand-foot-mouth disease (HFMD) is an acute communicable disease, mostly affecting children under 5 years of age and caused by human enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16). The usual incubation period is 3 to 7 days. Early symptoms are likely to be fever often followed by a sore throat followed by loss of appetite and general malaise. Aim and objectives was to study the trend of hand foot and mouth disease in a private hospital in Uttarakhand over 5 successive years.Methods: This cross-sectional study was carried among 297 cases of HFMD newborn screened at pediatrics department of Sahota Super-specialty hospital, Kashipur, Uttarakhand during year 2015 to 2019 after ethical clearance of institutional ethical committee. Diagnosis is coded with ICD-10. SPSS version 20 was used to calculate frequencies and percentiles.Results: Almost 29 cases of HMFD were picked in 2015, 32 cases in 2016, 43 cases in 2017, 81 cases in 2018, 112 in 2019. Fever observed in 86% cases. Neurological complications were observed in 9 (3%) cases, pneumonitis in 14 (4.7%) cases, cardiomyopathy observed in 3 (<1%) case. One death was reported.Conclusions: It is vital to screen patients with HFMD for these abnormal clinical presentations, allowing timely initiation of appropriate interventions to reduce the mortality. Increased awareness about vaccination in a developing nation like India and vaccination program at the grass root levels have eradicated certain lethal diseases.

scholarly journals Complete genome analysis demonstrates multiple introductions of enterovirus 71 and coxsackievirus A16 recombinant strains into Thailand during the past decade

2018 ◽  
Vol 7 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Pirom Noisumdaeng ◽  
Kantima Sangsiriwut ◽  
Jarunee Prasertsopon ◽  
Chompunuch Klinmalai ◽  
Sunchai Payungporn ◽  
...  
Keyword(s):  
Genome Analysis ◽  
Complete Genome ◽  
Enterovirus 71 ◽  
Coxsackievirus A16 ◽  
Multiple Introductions ◽  
Recombinant Strains ◽  
The Past ◽  
Complete Genome Analysis

scholarly journals Hand, Foot and Mouth Disease (HFMD): An Update

2017 ◽  
Vol 40 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Probir Kumar Sarkar ◽  
Nital Kumar Sarker ◽  
Md Abu Tayab
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Coxsackie Virus ◽  
Asia Pacific ◽  
Human Enterovirus ◽  
Small Scale ◽  
Human Enterovirus 71 ◽  
Mild Disease ◽  
Foot And Mouth

Hand, foot, and mouth disease (HFMD) also known as vesicular stomatitis with exanthema, first reported in New Zealand in 1957 is caused by Coxsackie virus A16 (CVA16), human enterovirus 71 (HEV71) and occasionally by other HEV-A serotypes, such as Coxsackie virus A6 and Coxsackie virus A10, are also associated with HFMD and herpangina. While all these viruses can cause mild disease in children, EV71 has been associated with neurological disease and mortality in large outbreaks in the Asia Pacific region over the last decade. It is highly contagious and is spread through direct contact with the mucus, saliva, or feces of an infected person. This is characterized by erythrematous papulo vesicular eruptions over hand, feet, perioral area, knee, buttocks and also intra-orally mostly in children, typically occurs in small epidemics usually during the summer and autumn months. HFMD symptoms are usually mild and resolve on their own in 7 to 10 days. Treatment is symptomatic but good hygiene during and after infection is very important in preventing the spread of the disease. Though only small scale outbreaks have been reported from United States, Europe, Australia Japan and Brazil for the first few decade, since 1997 the disease has conspicuously changed its behavior as noted in different Southeast Asian countries. There was sharp rise in incidence, severity, complications and even fatal outcomes that were almost unseen before that period. There are reports of disease activity in different corners of India since 2004, and the largest outbreak of HFMD occurred in eastern part of India in and around Kolkata in 2007and Bhubaneswar, Odisha in 2009. In recent years there are cases of HFMD have been seen in Bangladesh also. Although of milder degree, continuous progress to affect larger parts of the neighboring may indicate vulnerability of Bangladesh from possible future outbreaks.Bangladesh J Child Health 2016; VOL 40 (2) :115-119

scholarly journals An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China

2010 ◽  
Vol 7 (1) ◽  
pp. 94 ◽  
Author(s):  
Yan Zhang ◽  
Zhen Zhu ◽  
Weizhong Yang ◽  
Jun Ren ◽  
Xiaojuan Tan ◽  
...  
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Human Enterovirus ◽  
Human Enterovirus 71 ◽  
Foot And Mouth
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