scholarly journals Synthesis of bis-amino acid derivatives by Suzuki cross-coupling, Michael addition and substitution reactions

Amino Acids ◽  
2008 ◽  
Vol 36 (3) ◽  
pp. 429-436 ◽  
Author(s):  
P. M. T. Ferreira ◽  
L. S. Monteiro ◽  
M.-J. R. P. Queiroz ◽  
G. Pereira
Keyword(s):  
Amino Acid ◽  
Michael Addition ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Substitution Reactions

Highly Stereoselective Michael Addition Reactions of CamTHP*-Desymmetrized Glycinamide for the Synthesis of Functionally Dense Amino Acid Derivatives

2004 ◽  
Vol 6 (24) ◽  
pp. 4427-4429 ◽  
Author(s):  
Darren J. Dixon ◽  
Richard A. J. Horan ◽  
Nathaniel J. T. Monck ◽  
Paul Berg
Keyword(s):  
Amino Acid ◽  
Michael Addition ◽  
Amino Acid Derivatives ◽  
Addition Reactions

Enantioselective conjugate addition of hydroxylamines to α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal Rh(iii) complex

2017 ◽  
Vol 4 (4) ◽  
pp. 573-577 ◽  
Author(s):  
Tao Deng ◽  
Ganesh Kumar Thota ◽  
Yi Li ◽  
Qiang Kang
Keyword(s):  
Amino Acid ◽  
Michael Addition ◽  
Conjugate Addition ◽  
Amino Acid Derivatives ◽  
Highly Efficient

A highly efficient chiral-at-metal Rh(iii) complex catalyzed asymmetric aza-Michael addition was developed, affordingN-protected β-amino acid derivatives with excellent enantioselectivity.

scholarly journals Substrate-controlled Diastereoselective Michael Addition of Alkylidene Malonates by Grignard Reagents

2019 ◽  
Vol 25 (1) ◽  
pp. 116-121
Author(s):  
Wei Zhou ◽  
Qingwei Xiao ◽  
Yuanyuan Chang ◽  
Qifa Liu ◽  
Xiaohao Zang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Michael Addition ◽  
Chiral Auxiliary ◽  
Grignard Reagents ◽  
Amino Acid Derivatives ◽  
Catalyst Free ◽  
Chemical Efficiency

AbstractHerein is described a diastereoselective Michael addition of Grignard reagents to α, β- unsaturated diethyl malonates incorporated with a 2-oxazolidone chiral auxiliary. The catalyst-free Michael addition proceeds with good chemical efficiency and excellent stereoselectivity; and it provides new thoughts to the asymmetric synthesis of β-substituted β3 amino acid derivatives.

Straightforward synthesis of fluorinated amino acids by Michael addition of ethyl bromodifluoroacetate to α,β-unsaturated α-amino acid derivatives

2018 ◽  
Vol 211 ◽  
pp. 100-108 ◽  
Author(s):  
Ivan S. Kondratov ◽  
Maxym Ya. Bugera ◽  
Nataliya A. Tolmachova ◽  
Constantin G. Daniliuc ◽  
Günter Haufe
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Michael Addition ◽  
Amino Acid Derivatives ◽  
Fluorinated Amino Acids

Iron-Catalyzed Oxidative CH/CH Cross-Coupling: An Efficient Route to α-Quaternary α-Amino Acid Derivatives

2013 ◽  
Vol 52 (49) ◽  
pp. 12942-12945 ◽  
Author(s):  
Kaizhi Li ◽  
Guangying Tan ◽  
Jingsheng Huang ◽  
Feijie Song ◽  
Jingsong You
Keyword(s):  
Amino Acid ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Efficient Route
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