Palladium-Catalyzed Regio- and Stereoselective Cross-Coupling of Vinylethylene Carbonates with Ketimine Esters to Generate (Z)-Tri- and Tetra-substituted Allylic Amino Acid Derivatives

2020 ◽  
Vol 22 (11) ◽  
pp. 4135-4140
Author(s):  
Miaolin Ke ◽  
Zhigang Liu ◽  
Guanxin Huang ◽  
Jiaqi Wang ◽  
Yuan Tao ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cross Coupling ◽  
Amino Acid Derivatives ◽  
Palladium Catalyzed

Palladium‐Catalyzed Allylic Alkylation of Aldimine Esters with Vinyl‐Cyclopropanes to Yield α,α‐Disubstituted α‐Amino Acid Derivatives

2019 ◽  
Vol 361 (22) ◽  
pp. 5105-5111 ◽  
Author(s):  
Jiahua Wang ◽  
Zonghao Dai ◽  
Cheng Xiong ◽  
Jin Zhu ◽  
Jinrong Lu ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Allylic Alkylation ◽  
Palladium Catalyzed

Palladium-Catalyzed Intermolecular Aminocarbonylation of Alkenes: Efficient Access of β-Amino Acid Derivatives

2015 ◽  
Vol 137 (7) ◽  
pp. 2480-2483 ◽  
Author(s):  
Jiashun Cheng ◽  
Xiaoxu Qi ◽  
Ming Li ◽  
Pinhong Chen ◽  
Guosheng Liu
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Efficient Access ◽  
Palladium Catalyzed

Synthesis of Chiral β-Fluoroalkyl β-Amino Acid Derivatives via Palladium-Catalyzed Hydrogenation

2019 ◽  
Vol 84 (16) ◽  
pp. 10371-10379 ◽  
Author(s):  
Mu-Wang Chen ◽  
Qin Yang ◽  
Zhihong Deng ◽  
Qiuping Ding ◽  
Yiyuan Peng
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Palladium Catalyzed

Palladium-Catalyzed Decarbonylation of Amino Acid Derivatives via C–C Bond and C–N Bond Dual Activations

2021 ◽  
Author(s):  
Jiamin Wu ◽  
Jinli Zhang ◽  
Yongjuan Jiao ◽  
Gongtao Deng ◽  
Yingmei Li ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Palladium Catalyzed

scholarly journals Palladium-catalyzed C–N and C–O bond formation of N-substituted 4-bromo-7-azaindoles with amides, amines, amino acid esters and phenols

2012 ◽  
Vol 8 ◽  
pp. 2004-2018 ◽  
Author(s):  
Rajendra Surasani ◽  
Dipak Kalita ◽  
A V Dhanunjaya Rao ◽  
K B Chandrasekhar
Keyword(s):  
Amino Acid ◽  
Bond Formation ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Amino Acid Esters ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed ◽  
Acid Esters

Simple and efficient procedures for palladium-catalyzed cross-coupling reactions of N-substituted 4-bromo-7-azaindole (1H-pyrrole[2,3-b]pyridine), with amides, amines, amino acid esters and phenols through C–N and C–O bond formation have been developed. The C–N cross-coupling reaction of amides, amines and amino acid esters takes place rapidly by using the combination of Xantphos, Cs2CO3, dioxane and palladium catalyst precursors Pd(OAc)2/Pd2(dba)3. The combination of Pd(OAc)2, Xantphos, K2CO3 and dioxane was found to be crucial for the C–O cross-coupling reaction. This is the first report on coupling of amides, amino acid esters and phenols with N-protected 4-bromo-7-azaindole derivatives.

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