Antibiotic therapy in fully impacted lower third molar surgery: randomized three-arm, double-blind, controlled trial

2015 ◽  
Vol 19 (4) ◽  
pp. 341-346 ◽  
Author(s):  
Basílio Almeida Milani ◽  
Henrique Camargo Bauer ◽  
Hélio Sampaio-Filho ◽  
Anna Carolina Ratto Tempestini Horliana ◽  
Flávio Eduardo Guillin Perez ◽  
...  
2020 ◽  
pp. 1-10
Author(s):  
E. Ferrés-Amat ◽  
J. Espadaler-Mazo ◽  
J.L. Calvo-Guirado ◽  
E. Ferrés-Amat ◽  
J. Mareque-Bueno ◽  
...  

The aim of this study was to investigate the effect of a probiotic in preventing infections after third molar surgery. Thirty-eight patients were consecutively enrolled to a double-blind randomised placebo-controlled trial. Patients were asked to take one tablet two times a day containing a mixture of Levilactobacillus brevis CECT7480 (KABP-052) and Lactoplantibacillus plantarum CECT7481 (KABP-051) or placebo for the first post-intervention week. The primary outcome was the postoperative infection rate. Secondary outcomes included swelling, eating difficulties and postoperative pain recorded by the patient using a visual analogue scale (VAS) during the first postoperative week. No statistically significant difference in the infection rate between the groups was found; with only three cases of infections reported (one in the probiotic group and two in the placebo group) on the first week. Compared to placebo, treatment with the probiotic showed a significantly higher reduction in pain and eating difficulties scores at 5, 6 and 7 days post-surgery. Swelling values were not significantly different between the groups at any time point. The findings of this pilot study justify a larger study to clarify the possible role of these bacterial strains on the post-operative pain management following third molar surgery.


Author(s):  
Shivangi Gaur ◽  
Madhulaxmi Marimuthu ◽  
P Wahab ◽  
Dr Navaneetha Krishnan ◽  
Subhashini Ramasubbu

Sign in / Sign up

Export Citation Format

Share Document