The significance of urinary beta-2 microglobulin level for differential diagnosis of familial Mediterranean fever and acute appendicitis

2016 ◽  
Vol 35 (7) ◽  
pp. 1669-1672 ◽  
Author(s):  
Yunus Ugan ◽  
Hakan Korkmaz ◽  
Atalay Dogru ◽  
Yavuz Savas Koca ◽  
Ayse Balkarlı ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Acute Appendicitis ◽  
Mediterranean Fever ◽  
Beta 2 ◽  
Beta 2 Microglobulin

scholarly journals The evaluation of ENA-78 and fibrinogen levels for the differential diagnosis of familial Mediterranean fever and acute appendicitis

2019 ◽  
Vol 43 (3) ◽  
pp. 141-147
Author(s):  
Murat Güzel ◽  
Recep Aktimur ◽  
Kadir Yıldırım ◽  
Sude Hatun Aktimur ◽  
Mehmet Hakan Taşkın ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Acute Appendicitis ◽  
Acute Peritonitis ◽  
Significant Difference ◽  
Mediterranean Fever ◽  
Group 2 ◽  
Wbc Count ◽  
Higher Sensitivity ◽  
Group 1

Abstract Background Familial Mediterranean fever (FMF) is a disorder mainly present in the Mediterranean region, characterized by abdominal attacks that mimic acute peritonitis. Therefore, FMF might be confused with other conditions presenting with acute abdominal pain, particularly acute appendicitis (AA). We aimed to evaluate whether epithelial-derived neutrophil-activating peptide-78 (ENA-78) and fibrinogen levels and white blood cell (WBC) counts could be used as potential markers in the differential diagnosis of acute FMF attacks and AA. Methods The study involved three groups: patients with AA who underwent surgery (group 1, n = 30), patients with FMF attacks (group 2, n = 30), and patients with FMF who were attack-free (n = 30, controls), which included patients who were diagnosed as having FMF previously but had no attacks for a month. Results Significant differences were detected in the ENA-78 and fibrinogen levels between group 1 and group 2. No significant difference was found in the WBC count between group 1 and group 2. It was concluded that the WBC count was more sensitive (66%) for group 1, and fibrinogen showed higher sensitivity (86%) and specificity (96%) for group 2 compared with the other parameters. Conclusions We suggest that AA can be distinguished in patients with signs of peritonitis who were diagnosed as having FMF previously with the use of ENA-78 and fibrinogen levels; fibrinogen and ENA-78 might be helpful in discriminating between FMF attacks and AA.

Resistin and visfatin: are they valuable enough to be the differential diagnosis in familial Mediterranean fever with acute appendicitis?

2011 ◽  
Vol 31 (2) ◽  
pp. 225-229 ◽  
Author(s):  
Bunyamin Kisacik ◽  
Mehmet Fatih Erol ◽  
Gulsen Yilmaz ◽  
Fatma Meric Yilmaz ◽  
Yuksel Maras ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Acute Appendicitis ◽  
Mediterranean Fever

scholarly journals Beta-2-Microglobulin Levels of Dialysis Patients with Renal Amyloidosis Secondary to Familial Mediterranean Fever

Nephron ◽  
1994 ◽  
Vol 68 (1) ◽  
pp. 152-152
Author(s):  
Cem Sungur ◽  
Seza Ozen ◽  
Cumhur Ozkuyumcu ◽  
Tekin Akpolat ◽  
Unal Yasavul ◽  
...  
Keyword(s):  
Familial Mediterranean Fever ◽  
Renal Amyloidosis ◽  
Dialysis Patients ◽  
Mediterranean Fever ◽  
Beta 2 ◽  
Beta 2 Microglobulin

Sacroiliitis in familial Mediterranean fever and seronegative spondyloarthropathy: importance of differential diagnosis

2005 ◽  
Vol 25 (8) ◽  
pp. 641-644 ◽  
Author(s):  
Birol Balaban ◽  
Evren Yasar ◽  
Ahmet Ozgul ◽  
Kemal Dincer ◽  
Tunc Alp Kalyon
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Seronegative Spondyloarthropathy ◽  
Mediterranean Fever

scholarly journals Familial Mediterranean Fever Is Important in the Differential Diagnosis of Recurrent Aseptic Meningitis in Japan

2020 ◽  
Vol 59 (1) ◽  
pp. 125-128
Author(s):  
Takahiro Hosoi ◽  
Kazuhiro Ishii ◽  
Naoki Tozaka ◽  
Dai Kishida ◽  
Yoshiki Sekijima ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Familial Mediterranean Fever ◽  
Aseptic Meningitis ◽  
Mediterranean Fever ◽  
Recurrent Aseptic Meningitis

scholarly journals Diffuse Skin Tightness in Familial Mediterranean Fever: A Case Report and Review of Literature

2015 ◽  
Vol 4 (4) ◽  
pp. 169-72
Author(s):  
Elham Behrangi ◽  
Nasrin Shayanfar ◽  
Hadi Mohagheghian Yaghoubi ◽  
Saman Aghabekloo ◽  
Zahra Azizian
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Systemic Sclerosis ◽  
Familial Mediterranean Fever ◽  
Physical Examination ◽  
Autosomal Recessive ◽  
Review Of Literature ◽  
Case Presentation ◽  
Tight Skin ◽  
Mediterranean Fever

Introduction: Familial Mediterranean Fever (FMF) is an autosomal recessive inherited disorder that has skin presentations like vasculitis and paniculitis. There has not been shown any association between systemic sclerosis and FMF in studies. Hence, we report a case of FMF with diffuse skin tightness. Case Presentation: An 18-year-old girl known as a case of FMF for 3 years presents to our department with tight skin since childhood. The stiffness of skin appeared when she was about 7 years old. In physical examination, tight skin with general induration in all surfaces of skin, sclerodactyly and beaked nose microstomia are noticed. The findings of all hematological, biochemical and pathological studies were normal. Conclusion: Finally, it may be concluded that FMF should be considered as a differential diagnosis in patients attending with skin tightness and the possible etiology is cytokines. [GMJ.2015;4(4):169-72]

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