Association of torque teno virus (TTV) and torque teno mini virus (TTMV) with liver disease among patients coinfected with human immunodeficiency virus and hepatitis C virus

2012 ◽  
Vol 32 (2) ◽  
pp. 289-297 ◽  
Author(s):  
M. García-Álvarez ◽  
J. Berenguer ◽  
E. Álvarez ◽  
M. Guzmán-Fulgencio ◽  
J. Cosín ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Torque Teno Virus ◽  
Immunodeficiency Virus

Liver histopathology in human immunodeficiency virus-hepatitis C virus co-infected patients with fatal liver disease

2005 ◽  
Vol 20 (5) ◽  
pp. 739-745 ◽  
Author(s):  
MATHIAS LICHTERFELD ◽  
SUSANNE HAAS ◽  
HANS-PETER FISCHER ◽  
ESTER VOIGT ◽  
JURGEN K ROCKSTROH ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Virus Hepatitis ◽  
Fatal Liver ◽  
Liver Histopathology ◽  
Immunodeficiency Virus

Cellular and molecular interactions in coinfection with hepatitis C virus and human immunodeficiency virus

2008 ◽  
Vol 10 ◽  
Author(s):  
Barbara Roe ◽  
William W. Hall
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Immune Responses ◽  
Molecular Mechanisms ◽  
Direct Result ◽  
Rapid Progression ◽  
Immunodeficiency Virus ◽  
Apoptotic Pathways

Coinfection with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is associated with increased HCV replication and a more rapid progression to severe liver disease, including the development of cirrhosis and hepatocellular carcinoma. In this review, we discuss the current understanding of the pathogenesis of HCV/HIV coinfection and the cellular and molecular mechanisms associated with the accelerated course of liver disease. The strength and breadth of HCV-specific T-cell responses are reduced in HCV/HIV-coinfected patients compared with those infected with HCV alone, suggesting that the immunosuppression induced by HIV compromises immune responses to HCV. HCV is not directly cytopathic, but many of the pathological changes observed in the liver of infected patients are a direct result of the intrahepatic antiviral immune responses. Apoptosis also has a role in HCV-mediated liver damage through the induction of apoptotic pathways involving the host immune response and HCV viral proteins. This review summarises the evidence correlating the role of cell-mediated immune responses and apoptosis with liver disease progression in HCV/HIV-coinfected patients.

IL28B polymorphisms are associated with severity of liver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus

2013 ◽  
Vol 66 (2) ◽  
pp. 170-178 ◽  
Author(s):  
María Guzmán-Fulgencio ◽  
Juan Berenguer ◽  
Mónica García-Álvarez ◽  
Amanda Fernández-Rodríguez ◽  
María A. Jiménez-Sousa ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Hiv Patients ◽  
Immunodeficiency Virus
Sign in / Sign up

Export Citation Format

Share Document