Combined craniofacial resection of anterior skull base tumors: long-term results and experience of single institution

2010 ◽  
Vol 34 (1) ◽  
pp. 101-113 ◽  
Author(s):  
Bashar Abuzayed ◽  
Bulent Canbaz ◽  
Galip Zihni Sanus ◽  
Seckin Aydin ◽  
Harun Cansiz
2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P37-P37
Author(s):  
Marc A. Cohen ◽  
Jonathan Liang ◽  
Bert W O'Malley ◽  
Jason G Newman

Objective 1) Learn if margins of resection in anterior skull base tumors that are entirely or endoscopic-assisted are comparable with those undergoing traditional craniofacial resection. 2) Understand if there is a difference in patient mortality with traditional CFR compared to endoscopic-assisted surgery. Methods Retrospective review was conducted of patients undergoing surgery at our institution for malignant lesions of the anterior skull base between 2000–2006. 46 patients were identified. 20 underwent endoscopic-assisted or total endoscopic resection. Margins were evaluated by the pathologist. Recurrence rates were calculated based on the presence or absence of recurrence at the last office visit. Follow-up times ranged from 1 month to 5 years. Results Of the 20 patients undergoing endoscopic or endoscopic assisted CFR of anterior skull base lesions, 15/20 patients had negative margins (75%), 4/20 had positive margins (20%), and 1/20 had close margins (5%). In those patients undergoing traditional CFR, 17/26 patients had negative margins (65%), 8/26 had positive margins (30%), and 1/26 (4%) had close margins. Recurrence was noted in 9/26 (35%) of those who underwent traditional CFR and 6/20 (30%) of those with endoscopic assistance. Conclusions There does not appear to be increased risk of positive margins or recurrence in those undergoing endscopic or endoscopic-assisted resection. Endoscopy may aid in identifying margins of tumor in the anterior skull base, leading to a greater likelihood of cure. Endoscopic resections have the potential to avoid morbity and should be considered oncologically sound in the appropriate patient with a skull base lesion.


1988 ◽  
Vol 10 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Narayan Sundaresan ◽  
Jatin P. Shah

2011 ◽  
Vol 3 (3) ◽  
pp. 156-160
Author(s):  
Aliasgar Moiyadi ◽  
Deepa Nair ◽  
Prathamesh S Pai

ABSTRACT Management of anterior skull base tumors has progressed steadily since AS Ketcham popularized the craniofacial surgical technique in the seventies with good results. In the past two decades, endoscopic sinonasal tumor resection has been established as an additional treatment option. For tumors that cross the anterior skull base, a cranial access is vital to encompass the tumor all around. For a select group of these transcranial lesions, the sinonasal component is suitable for an endoscopic endonasal oncologically safe resection along with a traditional transcranial access to complete the resection. This article endeavors to describe the endoscopicassisted craniofacial combining the advantages of a transnasal minimal access to reduce facial morbidity and the transcranial access for superior control of tumors with adequate margins.


1995 ◽  
Vol 82 (6) ◽  
pp. 1002-1010 ◽  
Author(s):  
Joram Raveh ◽  
Jon B. Turk ◽  
Kurt Lädrach ◽  
Rolf Seiler ◽  
Nelson Godoy ◽  
...  

✓ The extended anterior subcranial approach differs significantly from more traditional surgical approaches to the skull base in that it allows a broad inferior access to the anterior skull base planes with tumor exposure from below rather than via the transfrontal route. The authors initially used the subcranial approach in 1978 for the treatment of high-velocity skull base trauma and certain craniofacial anomalies. In 1980 they expanded the indications to include the combined neurosurgical—otolaryngological resection of various skull base tumors. Osteotomy of the frontonasoorbital external skeletal frame provides optimum anterior access to the orbital and sphenoethmoidal planes as well as to the nasal and paranasal cavities while avoiding frontal lobe retraction and the external facial incisions characteristic of transcranial and transfacial approaches. The improved visualization of the anterior skull base and clival—sphenoidal region facilitates en bloc tumor removal, optic nerve decompression, exposure of the medial aspect of the cavernous sinus, and watertight realignment of the anterior cranial base dura. In this report the authors present their experience over the past 13 years with 104 patients who underwent operation via the extended subcranial approach. Because extensive frontal lobe manipulation and external facial incisions are avoided with this approach, intensive care unit and overall hospital stay are reduced, related complications are minimized, and postoperative cosmetic appearance is enhanced. The extended anterior subcranial method is therefore an excellent alternative to traditional transfacial-transcranial skull base approaches for the removal of selected skull base tumors.


1996 ◽  
Vol 75 (6) ◽  
pp. 377-380 ◽  
Author(s):  
Laurence J. DiNardo ◽  
Robert L. Rumsey

The evolution of skull base surgery has facilitated the extirpation of previously unresectable tumors. As experience with skull base surgery increases, the feasibility of resection and long-term outcomes is becoming apparent for the more common lesions. Neoplasms such as malignant schwannomas are rare and, therefore, defy single-institution analysis. The treatment and four-year follow-up of a malignant paranasal sinus and anterior skull base schwannoma is described. Analysis of the literature confirms the low incidence of this tumor and supports the efficacy of skull base surgery in its treatment.


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