The incidence of postoperative cerebrospinal fluid leakage after elective cranial surgery: a systematic review

2021 ◽  
Author(s):  
Birgit Coucke ◽  
Lura Van Gerven ◽  
Steven De Vleeschouwer ◽  
Frank Van Calenbergh ◽  
Johannes van Loon ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage ◽  
Cranial Surgery

scholarly journals Cerebrospinal fluid leakage after cranial surgery in the pediatric population—a systematic review and meta-analysis

2021 ◽  
Author(s):  
Emma M. H. Slot ◽  
Kirsten M. van Baarsen ◽  
Eelco W. Hoving ◽  
Nicolaas P. A. Zuithoff ◽  
Tristan P. C van Doormaal
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Cerebrospinal Fluid ◽  
Pediatric Population ◽  
Meta Analysis ◽  
Leakage Rate ◽  
Csf Leak ◽  
Cerebrospinal Fluid Leakage ◽  
Cranial Surgery ◽  
Csf Leakage

Abstract Background Cerebrospinal fluid (CSF) leakage is a common complication after neurosurgical intervention. It is associated with substantial morbidity and increased healthcare costs. The current systematic review and meta-analysis aim to quantify the incidence of cerebrospinal fluid leakage in the pediatric population and identify its risk factors. Methods The authors followed the PRISMA guidelines. The Embase, PubMed, and Cochrane database were searched for studies reporting CSF leakage after intradural cranial surgery in patients up to 18 years old. Meta-analysis of incidences was performed using a generalized linear mixed model. Results Twenty-six articles were included in this systematic review. Data were retrieved of 2929 patients who underwent a total of 3034 intradural cranial surgeries. Surprisingly, only four of the included articles reported their definition of CSF leakage. The overall CSF leakage rate was 4.4% (95% CI 2.6 to 7.3%). The odds of CSF leakage were significantly greater for craniectomy as opposed to craniotomy (OR 4.7, 95% CI 1.7 to 13.4) and infratentorial as opposed to supratentorial surgery (OR 5.9, 95% CI 1.7 to 20.6). The odds of CSF leakage were significantly lower for duraplasty use versus no duraplasty (OR 0.41 95% CI 0.2 to 0.9). Conclusion The overall CSF leakage rate after intradural cranial surgery in the pediatric population is 4.4%. Risk factors are craniectomy and infratentorial surgery. Duraplasty use is negatively associated with CSF leak. We suggest defining a CSF leak as “leakage of CSF through the skin,” as an unambiguous definition is fundamental for future research.

scholarly journals Effectiveness of Dural Sealants in Prevention of Cerebrospinal Fluid Leakage After Craniotomy: A Systematic Review

2018 ◽  
Vol 118 ◽  
pp. 368-376.e1 ◽  
Author(s):  
Ahmet Kinaci ◽  
Ale Algra ◽  
Simon Heuts ◽  
Devon O'Donnell ◽  
Albert van der Zwan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage

scholarly journals Effectiveness of Sealants in Prevention of Cerebrospinal Fluid Leakage after Spine Surgery: A Systematic Review

2019 ◽  
Vol 127 ◽  
pp. 567-575.e1 ◽  
Author(s):  
Ahmet Kinaci ◽  
Nizar Moayeri ◽  
Albert van der Zwan ◽  
Tristan P.C. van Doormaal
Keyword(s):  
Systematic Review ◽  
Cerebrospinal Fluid ◽  
Spine Surgery ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage

Traumatic Cerebrospinal Fluid Leakage

1983 ◽  
Vol 16 (3) ◽  
pp. 623-632 ◽  
Author(s):  
James Ryan Chandler
Keyword(s):  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage

Skull Base Abnormalities Associated with Spontaneous Cerebrospinal Fluid Leakage

2012 ◽  
Vol 73 (S 02) ◽  
Author(s):  
A. Patrona ◽  
K. Schwager ◽  
R. Behr
Keyword(s):  
Cerebrospinal Fluid ◽  
Skull Base ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage

Cerebrospinal Fluid Leakage

2020 ◽  
Author(s):  
Keyword(s):  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage

Preventive Management of Cerebrospinal Fluid Leakage in Translabyrinthine Surgery

1996 ◽  
Vol 106 (5) ◽  
pp. 610-613 ◽  
Author(s):  
Lance R. Meyerson ◽  
Edwin M. Monsell ◽  
Jack P. Rock
Keyword(s):  
Cerebrospinal Fluid ◽  
Cerebrospinal Fluid Leakage ◽  
Fluid Leakage
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