Self-Healing Congenital Langerhans Cell Histiocytosis Presenting as Neonatal Papulovesicular Eruption

2001 ◽  
Vol 5 (6) ◽  
pp. 486-489 ◽  
Author(s):  
Kelli W. Morgan ◽  
Jeffrey P. Callen
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Self Healing

Acral, Pure Cutaneous, Self-Healing, Late-Onset, Cellulitis-Like Langerhans Cell Histiocytosis

2009 ◽  
Vol 13 (1) ◽  
pp. 43-47
Author(s):  
Prafulla Kumar Sharma ◽  
Sunil Sabhnani ◽  
Minakshi Bhardwaj ◽  
Hemanta Kumar Kar
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Clinical Presentation ◽  
Late Onset ◽  
Early Adulthood ◽  
Langerhans Cell ◽  
Self Healing ◽  
Diagnostic Dilemma

Background: An unusual and not yet reported clinical presentation of pure cutaneous Langerhans cell histiocytosis (LCH) that was a diagnostic dilemma. Objective: To bring to light the newer presentation of this disease. Method: The case was managed on clinical grounds initially as cellulitis. However, after the investigations and confirmation of the diagnosis, she was managed symptomatically. Results: Pure cutaneous LCH may manifest in early adulthood with features of cellulitis, erythematous edematous vesicular plaques, and nodules distributed in the flexural acral areas. Conclusion: Pure cutaneous LCH may have an acute late onset with unusual morphology as cellulitis, inverse acral distribution, and self-healing.

Self-Healing Congenital Langerhans Cell Histiocytosis Presenting as Neonatal Papulovesicular Eruption

2001 ◽  
Vol 5 (6) ◽  
pp. 486-489 ◽  
Author(s):  
Kelli W. Morgan ◽  
Jeffrey P. Callen
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Rare Condition ◽  
Signs And Symptoms ◽  
Male Infant ◽  
Skin Lesions ◽  
Langerhans Cell ◽  
Self Healing ◽  
Systemic Involvement ◽  
S 100 ◽  
Simplex Virus

Background: Congenital self-healing Langerhans cell histiocytosis (CSHLCH) is a rare condition which may present at birth or during the neonatal period. It is usually characterized by the eruption of multiple, disseminated, red-brown papules and nodules which may increase in size and number during the first few weeks of life. Systemic signs are usually absent except for occasional mild hepatomegaly. Objective: We present a 3.5-kg male infant who presented at birth with numerous diffuse, erythematous, crusted erosions. He was presumed to have congenital herpes simplex virus (HSV) and was started on IV acyclovir. Histopathologic examination revealed a mixed inflammatory infiltrate with numerous histiocytes which were S-100 and peanut agglutin positive consistent with CSHLCH. Further workup did not reveal any signs of systemic involvement. Conclusion: CSHLCH has rarely been reported to present as a papulovesicular eruption at birth. In these cases, a viral etiology is commonly entertained in the differential diagnosis. Despite the spontaneous regression of skin lesions in CSHLCH, close followup is required to evaluate for systemic signs and symptoms associated with latent Letterer–Siwe disease.

Congenital Langerhans Cell Histiocytosis: The Self-Healing Variety

2004 ◽  
Vol 26 (6) ◽  
pp. 398-402 ◽  
Author(s):  
Mandeep Walia ◽  
Premila Paul ◽  
Sharmila Mishra ◽  
Rajesh Mehta
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
The Self ◽  
Self Healing

Late-onset self-healing reticulohistiocytosis: Pediatric case of Hashimoto?Pritzker type Langerhans cell histiocytosis

2007 ◽  
Vol 34 (3) ◽  
pp. 205-209 ◽  
Author(s):  
Kyoko NAKAHIGASHI ◽  
Miyuki OHTA ◽  
Rie SAKAI ◽  
Yasushi SUGIMOTO ◽  
Yukiko IKOMA ◽  
...  
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Late Onset ◽  
Langerhans Cell ◽  
Self Healing ◽  
Pediatric Case

Congenital Self Healing Langerhans Cell Histiocytosis

2017 ◽  
Vol 85 (4) ◽  
pp. 316-317
Author(s):  
Sunil Gothwal ◽  
Anand Kumar Gupta ◽  
Ramesh Choudhary
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Self Healing

Late-onset self-healing Langerhans cell histiocytosis in a patient with atopic dermatitis

2014 ◽  
Vol 41 (5) ◽  
pp. 450-451 ◽  
Author(s):  
Takeshi Nakahara ◽  
Makiko Kido-Nakahara ◽  
Eriko Itoh ◽  
Masutaka Furue
Keyword(s):  
Atopic Dermatitis ◽  
Langerhans Cell Histiocytosis ◽  
Late Onset ◽  
Langerhans Cell ◽  
Self Healing

scholarly journals Langerhans Cell Histiocytosis of the Temporal Bone in Children: Two Cases Report

2021 ◽  
Vol 3 (3) ◽  
pp. 24-26
Author(s):  
Y. Labani ◽  
O. Oulghoul ◽  
O. Benhoummad ◽  
Y. Rochdi ◽  
A. Raji
Keyword(s):  
Computed Tomography ◽  
Temporal Bone ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Bone Lesions ◽  
Self Healing ◽  
Multisystem Disease ◽  
Inflammatory Polyp ◽  
First Case ◽  
Bone Biopsies

Langerhans cell histiocytosis is a rare hematologic disease due to multiplication and accumulation of Langerhans cells, which are immature dendritic cells. The clinical presentation is highly variable and can range from isolated, self-healing skin or bone lesions to life-threatening multisystem disease. We report 2 cases confirmed by Histological and immunohistochemical evaluation of temporal bone biopsies. The first case is a 2-year-old child with chronic bilateral otorrhea and polyuria-polydipsia syndrome. Physical examination showed bilateral retroauricular redness and induration with filling all of the right and left external ear canal. Computed tomography showed osseous lysis of the temporal bone bilaterally. Magnetic resonance imaging of the brain showed the presence of pituitary infiltration. The second case is 2-year-old girl with chronic left otorrhea. Clinical examination objectified the presence of redness and induration in the left mastoid with the presence of an inflammatory polyp filling the entire left external auditory canal. Computed tomography revealed a left temporal bone lysis. Both patients were treated with chemotherapy.

Congenital self-healing Langerhans cell histiocytosis: The need for a long term follow up

2003 ◽  
Vol 42 (3) ◽  
pp. 245-246 ◽  
Author(s):  
Margarita Larralde ◽  
Alicia Rositto ◽  
Margarita Giardelli ◽  
Carlos F. Gatti ◽  
Andrea Santos-Munoz
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Self Healing ◽  
Long Term Follow Up
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