scholarly journals A mixture approach to investigate interstitial growth in engineering scaffolds

2015 ◽  
Vol 15 (2) ◽  
pp. 259-278 ◽  
Author(s):  
Franck J. Vernerey
Keyword(s):  
Interstitial Growth

scholarly journals TINJAUAN HISTOLOGIK TULANG RAWAN

2014 ◽  
Vol 6 (3) ◽  
Author(s):  
Sonny J. R. Kalangi
Keyword(s):  
Cartilage Formation ◽  
Proliferation And Differentiation ◽  
Interstitial Growth ◽  
Cellular Condensation

Abstract: Cartilage belongs to the suppportive tissue which is relatively dense. In an adult, this tissue is only found in two areas: extraskeletal cartilage and joints. During chondrogenesis in an embryo, messenchymal cells round up, retract their extensions, multiply rapidly, and form cellular condensation, cartilage formation area. The development of this ares occurs in two mechanisms: interstitial growth and apppositional growth. Injured cartilage will be repaired by the perichondrium. Its cells tend to fill spaces or deffects meanwhile chondrogenic cells of the perichondrium will undergone proliferation and differentiation to become chondroblast which produces new matrix.Keywords: cartilage, types of cartilageAbstrak: Tulang rawan merupakan jaringan ikat penahan berat yang relatif padat, tetapi tidak sekuat tulang. Dalam kehidupan pasca lahir, jaringan ini hanya ditemukan pada dua jenis tempat sesudah tidak tumbuh lagi, yaitu pada sejumlah bangunan tulang rawan ekstra-skeletal yang terdapat dalam tubuh dan pada persendian. Pada tempat pembentukan tulang rawan embrio, sel-sel mesenkim menyusutkan cabang-cabangnya dan mengumpul dalam agregasi padat yang dikenal sebagai pusat kondrifikasi. Pertumbuhan dalam perluasan pusat kondrifikasi terjadi melalui dua mekanisme berbeda, yaitu: pertumbuhan interstitial dan pertumbuhan aposisional. Cedera tulang rawan akibat trauma akan diperbaiki oleh perikondrium. Sel-sel perikondrium cenderung untuk mengisi kekosongan atau defek, sedangkan sel-sel kondrogenik dalam perikondrium akan berproliferasi dan berdiferensiasi menjadi kondroblas yang menghasilkan matriks baru.Kata kunci: kartilago, jenis kartilago

Asymmetry Of The Node Of Ranvier

1968 ◽  
Vol 3 (3) ◽  
pp. 341-356
Author(s):  
P. L. WILLIAMS ◽  
R. KASHEF
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Cell Body ◽  
Node Of Ranvier ◽  
Laryngeal Nerve ◽  
Growth Patterns ◽  
Differential Growth ◽  
Nerve Roots ◽  
Preferred Direction ◽  
Symmetrical Condition ◽  
Interstitial Growth

The nodal constrictions of Ranvier in normal limb nerves of mammals are bounded by asymmetric paranodal bulbs, the proximal bulb (nearer the cell body) being larger in all dimensions. This investigation was undertaken to determine whether the asymmetry results from partial damming of proximo-distally flowing axoplasm at the nodal constriction, or whether other features of local growth patterns are more relevant. The degree of asymmetry was estimated on teased, osmicated fibres from normal immature and mature limb nerves to skin and muscle and on ventral nerve roots. Estimates were also made on the central processes of dorsal root ganglionic cells with their contrasting direction of flow, after alteration of growth patterns in regenerates of crushed immature and mature nerves, and in the recurrent laryngeal nerve which pursues an exceptional course in relation to surrounding tissues. A polarization of asymmetry with larger proximal bulbs was found in uncomplicated limb nerves and after simultaneous regeneration and limb growth following crushing of immature nerves. Mixed populations (that is, with no preferred direction of asymmetry and often symmetrical bulbs) were found in dorsal and ventral nerve roots and the apical recurved segment of the recurrent laryngeal, whilst the mature regenerates closely approached the symmetrical condition. The descending and ascending limbs of the recurrent laryngeal nerve showed a reversal of polarization with respect to the cell body, but similar with respect to the cephalo-caudal body axis. It was concluded that damming of directionally flowing axoplasm was not causally related to the formation of asymmetric bulbs. The overall interstitial growth pattern of limb nerve elongation as revealed by internodal distance studies contrasts with the differential growth and maturation gradients shown by the various limb segments through which the nerve passes. These differences result in a relative movement between the myelinating and elongating Schwann cell and the surrounding limb tissues. The movements are considerable and unidirectional throughout most of the limb, the Schwann cells becoming relatively further removed from the limb apex, whilst the movements minimize at the limb root and apex. It is suggested that the altered mechanical conditions operating at the ‘advancing’ and ‘trailing’ ends of the cell are related to the dimensional differences of the paranodal apparatus comprising the bulb at each end of the cell, and secondarily result in asymmetric nodes of Ranvier.

scholarly journals P-141 * INTERSTITIAL GROWTH PATTERN AS ONE OF THE INDICATORS OF MALIGNANCY IN PRIMARY LUNG CANCER

2014 ◽  
Vol 18 (suppl 1) ◽  
pp. S37-S37
Author(s):  
S. Suzuki ◽  
G. Ishii ◽  
K. Aokage ◽  
T. Hishida ◽  
J. Yoshida ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Growth Pattern ◽  
Primary Lung Cancer ◽  
Interstitial Growth

Interstitial Growth of Bone Revisited

2004 ◽  
Vol 15 (2) ◽  
pp. 283-287
Author(s):  
Bernard G. Sarnat
Keyword(s):  
Interstitial Growth

Pleural sarcomatoid mesothelioma with an interstitial growth pattern

2020 ◽  
Vol 70 (2) ◽  
pp. 126-128
Author(s):  
Keita Miyakawa ◽  
Masahiro Yamamoto ◽  
Naoko Akiyama ◽  
Masatoshi Sado ◽  
Sayaka Yuzawa ◽  
...  
Keyword(s):  
Growth Pattern ◽  
Interstitial Growth ◽  
Sarcomatoid Mesothelioma

Multigenerational Interstitial Growth of Biological Tissues

2010 ◽  
Author(s):  
Gerard A. Ateshian ◽  
Tim Ricken
Keyword(s):  
Constitutive Relations ◽  
Biological Tissues ◽  
Reference Configuration ◽  
Solid Matrix ◽  
Current Configuration ◽  
Interstitial Growth

The objective of this study is to formulate a theory for multigenerational interstitial growth of biological tissues whereby each generation has a distinct reference configuration determined at the time of its deposition. In this model, the solid matrix of a growing tissue consists of a multiplicity of intermingled bodies, each of which represents a generation, all of which are constrained to move together in the current configuration. This proposed framework builds on the concept of constrained mixtures of solids originally formulated by Humphrey and Rajagopal (2002). The specific aim is to determine the form of constitutive relations for the solid constituents of a multigenerational tissue, and provide simple illustrations of the theory.

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