scholarly journals TINJAUAN HISTOLOGIK TULANG RAWAN

2014 ◽  
Vol 6 (3) ◽  
Author(s):  
Sonny J. R. Kalangi

Abstract: Cartilage belongs to the suppportive tissue which is relatively dense. In an adult, this tissue is only found in two areas: extraskeletal cartilage and joints. During chondrogenesis in an embryo, messenchymal cells round up, retract their extensions, multiply rapidly, and form cellular condensation, cartilage formation area. The development of this ares occurs in two mechanisms: interstitial growth and apppositional growth. Injured cartilage will be repaired by the perichondrium. Its cells tend to fill spaces or deffects meanwhile chondrogenic cells of the perichondrium will undergone proliferation and differentiation to become chondroblast which produces new matrix.Keywords: cartilage, types of cartilageAbstrak: Tulang rawan merupakan jaringan ikat penahan berat yang relatif padat, tetapi tidak sekuat tulang. Dalam kehidupan pasca lahir, jaringan ini hanya ditemukan pada dua jenis tempat sesudah tidak tumbuh lagi, yaitu pada sejumlah bangunan tulang rawan ekstra-skeletal yang terdapat dalam tubuh dan pada persendian. Pada tempat pembentukan tulang rawan embrio, sel-sel mesenkim menyusutkan cabang-cabangnya dan mengumpul dalam agregasi padat yang dikenal sebagai pusat kondrifikasi. Pertumbuhan dalam perluasan pusat kondrifikasi terjadi melalui dua mekanisme berbeda, yaitu: pertumbuhan interstitial dan pertumbuhan aposisional. Cedera tulang rawan akibat trauma akan diperbaiki oleh perikondrium. Sel-sel perikondrium cenderung untuk mengisi kekosongan atau defek, sedangkan sel-sel kondrogenik dalam perikondrium akan berproliferasi dan berdiferensiasi menjadi kondroblas yang menghasilkan matriks baru.Kata kunci: kartilago, jenis kartilago

2005 ◽  
Vol 173 (4S) ◽  
pp. 387-387
Author(s):  
Quan Wu ◽  
Jian-Dang Shi ◽  
Yu Liu ◽  
Ke-Ming Wang ◽  
Helmut Klocker ◽  
...  

2020 ◽  
Vol 3 (2) ◽  
pp. 216-242 ◽  
Author(s):  
Mayuri Shukla ◽  
Areechun Sotthibundhu ◽  
Piyarat Govitrapong

The revelation of adult brain exhibiting neurogenesis has established that the brain possesses great plasticity and that neurons could be spawned in the neurogenic zones where hippocampal adult neurogenesis attributes to learning and memory processes. With strong implications in brain functional homeostasis, aging and cognition, various aspects of adult neurogenesis reveal exuberant mechanistic associations thereby further aiding in facilitating the therapeutic approaches regarding the development of neurodegenerative processes in Alzheimer’s Disease (AD). Impaired neurogenesis has been significantly evident in AD with compromised hippocampal function and cognitive deficits. Melatonin the pineal indolamine augments neurogenesis and has been linked to AD development as its levels are compromised with disease progression. Here, in this review, we discuss and appraise the mechanisms via which melatonin regulates neurogenesis in pathophysiological conditions which would unravel the molecular basis in such conditions and its role in endogenous brain repair. Also, its components as key regulators of neural stem and progenitor cell proliferation and differentiation in the embryonic and adult brain would aid in accentuating the therapeutic implications of this indoleamine in line of prevention and treatment of AD.   


2012 ◽  
Vol 34 (4) ◽  
pp. 454-464 ◽  
Author(s):  
Li WANG ◽  
Wei NA ◽  
Yu-Xiang WANG ◽  
Yan-Bo WANG ◽  
Ning WANG ◽  
...  

2011 ◽  
Vol 38 (10) ◽  
pp. 967-974
Author(s):  
Jian ZHOU ◽  
Hui-Ping MA ◽  
Ke-Ming CHEN ◽  
Bao-Feng GE ◽  
Guo-Zheng CHENG ◽  
...  

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