scholarly journals Clinical characteristics and risk factors of gastroesophageal reflux disease in Vietnamese patients with upper gastrointestinal symptoms undergoing esophagogastroduodenoscopy

JGH Open ◽  
2021 ◽  
Author(s):  
Duc T Quach ◽  
Quyen T T Pham ◽  
Truc L T Tran ◽  
Nhu T H Vu ◽  
Quang D Le ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Clinical Characteristics ◽  
Gastrointestinal Symptoms ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

scholarly journals Acute Effects of Red Chili, a Natural Capsaicin Receptor Agonist, on Gastric Accommodation and Upper Gastrointestinal Symptoms in Healthy Volunteers and Gastroesophageal Reflux Disease Patients

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3740
Author(s):  
Tanisa Patcharatrakul ◽  
Chatchai Kriengkirakul ◽  
Tawatchai Chaiwatanarat ◽  
Sutep Gonlachanvit
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Healthy Volunteers ◽  
Reflux Disease ◽  
Gastrointestinal Symptoms ◽  
Emission Computed Tomography ◽  
Transient Receptor Potential Vanilloid ◽  
Gastric Accommodation ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

The effects of chili on gastric accommodation (GA) in gastroesophageal reflux disease (GERD) patients have not been explored. Methods: In total, 15 healthy volunteers (HV) and 15 pH-positive non-erosive GERD (NERD) patients underwent single-photon emission computed tomography after ingesting 2 g of chili or placebo in capsules in a randomized double-blind crossover fashion with a one-week washout period. GA was the maximal postprandial gastric volume (GV) after 250 mL of Ensure® minus the fasting GV. Upper gastrointestinal symptoms were evaluated by using a visual analog scale. Results: NERD patients but not HV had significantly greater GA after chili compared to a placebo (451 ± 89 vs. 375 ± 81 mL, p < 0.05). After chili, the postprandial GVs at 10, 20, and 30 min in NERD patients were significantly greater than HV (10 min, 600 ± 73 vs. 526 ± 70 mL; 20 min, 576 ± 81 vs. 492 ± 78 mL; 30 min, 532 ± 81 vs. 466 ± 86 mL, all p < 0.05). In NERD, chili was associated with significantly less satiety, more severe abdominal burning (p < 0.05), and a trend of more severe heartburn (p = 0.06) compared to the placebo. In HV, postprandial symptoms after chili and placebo ingestion were similar (p > 0.05). Conclusions: Chili enhanced GA in NERD patients but not in HV. This suggests that the modulation of GA in NERD is abnormal and likely involves transient receptor potential vanilloid 1 (TRPV1) sensitive pathways.

scholarly journals Clinical Characteristics of Gastroesophageal Reflux Disease with Esophageal Injury in Korean: Focusing on Risk Factors

2011 ◽  
Vol 57 (5) ◽  
pp. 281 ◽  
Author(s):  
Seung Jun Lee ◽  
Min Kyu Jung ◽  
Sung Kook Kim ◽  
Byung Ik Jang ◽  
Si Hyung Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Clinical Characteristics ◽  
Esophageal Injury

scholarly journals Prevalence, clinical characteristics, and risk factors of Barrett esophagus in Vietnamese patients with upper gastrointestinal symptoms

Medicine ◽  
2020 ◽  
Vol 99 (34) ◽  
pp. e21791
Author(s):  
Duc T. Quach ◽  
Quyen T.T. Pham ◽  
Truc L.T. Tran ◽  
Nhu T.H. Vu ◽  
Quang D. Le ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Characteristics ◽  
Gastrointestinal Symptoms ◽  
Barrett Esophagus ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

scholarly journals Gastroesophageal Reflux Disease and Probiotics: A Systematic Review

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 132 ◽  
Author(s):  
Jing Cheng ◽  
Arthur C. Ouwehand
Keyword(s):  
Systematic Review ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Prospective Studies ◽  
Reflux Disease ◽  
Adult Population ◽  
Gastrointestinal Symptoms ◽  
Therapeutic Window ◽  
Jadad Scale ◽  
Upper Gastrointestinal

Probiotic is little known for its benefits on upper gastrointestinal health. The objective of this systematic review was to examine the efficacy of probiotics in alleviating the frequency and severity of symptoms in gastroesophageal reflux disease (GERD) in the general adult population. The PubMed and Web of Science databases were searched for prospective studies on GERD, heartburn, regurgitation, and dyspepsia, without any limitation on sample size. The Jadad scale was used to evaluate the quality of randomized controlled trials. In total, 13 prospective studies that were published in 12 articles were included in the analysis and scored per the Jadad scale as high- (five studies), medium- (two), and low- (six) quality. One article reported on two probiotic groups; thus, 14 comparisons were included in the selected studies, of which 11 (79%) reported positive benefits of probiotics on symptoms of GERD. Five out of 11 positive outcomes (45%) noted benefits on reflux symptoms: three noted reduced regurgitation; improvements in reflux or heartburn were seen in one study; five (45%) saw improvements in dyspepsia symptoms; and nine (81%) saw improvements in other upper gastrointestinal symptoms, such as nausea (three studies), abdominal pain (five), and gas-related symptoms (four), such as belching, gurgling, and burping. In conclusion, probiotic use can be beneficial for GERD symptoms, such as regurgitation and heartburn. However, proper placebo-controlled, randomized, and double-blinded clinical trials with a sufficient number of participants are warranted to confirm its efficacy in alleviating these symptoms. Further, interventions with longer durations and an intermediate analysis of endpoints should be considered to determine the proper therapeutic window.

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