Effect of Melafen on Structure and Function of Liposome and Ehrlich Ascitic Carcinoma Cell Membranes

2009 ◽  
Vol 147 (6) ◽  
pp. 742-745 ◽  
Author(s):  
O. M. Alekseeva ◽  
L. D. Fatkullina ◽  
Yu. A. Kim ◽  
E. B. Burlakova ◽  
S. G. Fattakhov ◽  
...  
1962 ◽  
Vol 40 (9) ◽  
pp. 1253-1260 ◽  
Author(s):  
A. S. V. Burgen

Permeation through cell membranes may occur through solution in membrane lipid, association with carrier molecules, formation of molecular dimers, passage through organized channels or through membrane translocation. It is probable that the predominant mechanism differs according to the type of cell.


1981 ◽  
Vol 15 (8) ◽  
pp. 1143-1149 ◽  
Author(s):  
R F A Zwaal

Author(s):  
Tatsuo Oguro ◽  
Kaoru Aihara ◽  
Kuniharu Aida ◽  
Goro Asano ◽  
Muhammad Ashraf

It has been suggested that hydrogen peroxide (H2O2) is indirectly associated with postischemicreperfusion injury of the heart. Previously, we reported that the heart was not damaged when perfused with exogenously generated superoxide anions. However, H2O2 which is a dismutation product of superoxide anion severely affected the heart structure and function, and the combined effects of H2O on membrane lipid and proteins result in the formation of membranous bleb.In this study, we evaluated the ultrastructural changes of the cell membranes in isolated rat hearts and cultured myocytes following treatment with exogenous H2O2. In the isolated hearts, 300μM H2O2 was perfused for 15 min and in the isolated cultured myocytes an equal amount of H2O2 was added to the culture medium for 30 min. This dosage of H2O2 was found to be injurious to the heart in our previous study. In the isolated cultured myocytes, 300μM H2O2 was added to the medium for 30 min.


1962 ◽  
Vol 40 (1) ◽  
pp. 1253-1260 ◽  
Author(s):  
A. S. V. Burgen

Permeation through cell membranes may occur through solution in membrane lipid, association with carrier molecules, formation of molecular dimers, passage through organized channels or through membrane translocation. It is probable that the predominant mechanism differs according to the type of cell.


Sign in / Sign up

Export Citation Format

Share Document