Decades of research, much of it in
Escherichia coli
, have yielded a wealth of insight into bacterial cell division. Here, we provide an overview of the
E. coli
division machinery with an emphasis on recent findings.
Abstract
Polymyxins are used as last-resort antibiotics, where other treatments have been ineffectual due to antibiotic resistance. However, resistance to polymyxins has also been now reported, therefore it is instructive to characterise at the molecular level, the mechanisms of action of polymyxins. Here we review insights into these mechanisms from molecular dynamics simulations and discuss the utility of simulations as a complementary technique to experimental methodologies.
Activation of a diluted E. coli cell-free transcription-translation system within liposomes by hypertonic concentration