Production of hydroxyapatite–bacterial cellulose composite scaffolds with enhanced pore diameters for bone tissue engineering applications

Cellulose ◽  
2019 ◽  
Vol 26 (18) ◽  
pp. 9803-9817 ◽  
Author(s):  
Ece Bayir ◽  
Eyup Bilgi ◽  
E. Esin Hames ◽  
Aylin Sendemir
Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1962 ◽  
Author(s):  
Abdullah M. Cakmak ◽  
Semra Unal ◽  
Ali Sahin ◽  
Faik N. Oktar ◽  
Mustafa Sengor ◽  
...  

Three-dimensional (3D) printing application is a promising method for bone tissue engineering. For enhanced bone tissue regeneration, it is essential to have printable composite materials with appealing properties such as construct porous, mechanical strength, thermal properties, controlled degradation rates, and the presence of bioactive materials. In this study, polycaprolactone (PCL), gelatin (GEL), bacterial cellulose (BC), and different hydroxyapatite (HA) concentrations were used to fabricate a novel PCL/GEL/BC/HA composite scaffold using 3D printing method for bone tissue engineering applications. Pore structure, mechanical, thermal, and chemical analyses were evaluated. 3D scaffolds with an ideal pore size (~300 µm) for use in bone tissue engineering were generated. The addition of both bacterial cellulose (BC) and hydroxyapatite (HA) into PCL/GEL scaffold increased cell proliferation and attachment. PCL/GEL/BC/HA composite scaffolds provide a potential for bone tissue engineering applications.


2016 ◽  
Vol 31 (8) ◽  
pp. 1148-1168 ◽  
Author(s):  
Engin Pazarçeviren ◽  
Özge Erdemli ◽  
Dilek Keskin ◽  
Ayşen Tezcaner

2009 ◽  
Vol 45 (3) ◽  
pp. 289-292 ◽  
Author(s):  
K. Madhumathi ◽  
P.T. Sudheesh Kumar ◽  
K.C. Kavya ◽  
T. Furuike ◽  
H. Tamura ◽  
...  

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