Complete response of hereditary leiomyomatosis and renal cell cancer (HLRCC)-associated renal cell carcinoma to nivolumab and ipilimumab combination immunotherapy by: a case report

2020 ◽  
Author(s):  
Yasuhiro Iribe ◽  
Mitsuko Furuya ◽  
Yousuke Shibata ◽  
Masato Yasui ◽  
Makoto Funahashi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Complete Response ◽  
Combination Immunotherapy ◽  
Hereditary Leiomyomatosis

scholarly journals A Case of Metastatic Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome-Associated Renal Cell Carcinoma Treated with a Sequence of Axitinib and Nivolumab Following Cytoreductive Nephrectomy

2020 ◽  
Vol 7 (2) ◽  
pp. 6-10
Author(s):  
Ichiro Yonese ◽  
Masaya Ito ◽  
Kosuke Takemura ◽  
Takao Kamai ◽  
Fumitaka Koga
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Fumarate Hydratase ◽  
Cancer Syndrome ◽  
Durable Response ◽  
Pelvic Cancer ◽  
Hereditary Leiomyomatosis

Hereditary leiomyomatosis and renal cell cancer syndrome (HLRCC) associated renal cell carcinoma (RCC) is an aggressive form of type 2 papillary RCC caused by deficiency of the fumarate hydratase gene. For patients with metastatic disease, no standard treatment has been established with dismal prognosis. We report a case of metastatic HLRCC-associated RCC in a 65-year-old Japanese male whose clinical features mimicked advanced renal pelvic cancer. A durable response was achieved with a sequence of axitinib and nivolumab after cytoreductive and diagnostic nephrectomy. Their potential therapeutic roles in the management of metastatic HLRCC-associated RCC have been discussed based on its molecular and biological backgrounds.

scholarly journals MP42-18 MANAGEMENT OF HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CANCER (HLRCC)-ASSOCIATED RENAL CELL CARCINOMA

2021 ◽  
Vol 206 (Supplement 3) ◽  
Author(s):  
Alexis Rompre-Brodeur ◽  
Jeunice Owens-Walton ◽  
Sandeep Gurram ◽  
Patrick T Gomella ◽  
Bradley R Webster ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer ◽  
Hereditary Leiomyomatosis

Hereditary leiomyomatosis and renal cell carcinoma syndrome: A case report

2008 ◽  
Vol 14 (1) ◽  
Author(s):  
Hayedeh Ghaninejad ◽  
Fatemeh Moeineddin ◽  
Ahmadreza Rajaee ◽  
Masoud Asgari ◽  
Ahmad Salimzadeh
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Hereditary Leiomyomatosis

Nephrectomy Followed by Interferon Alfa-2b Compared With Interferon Alfa-2b Alone for Metastatic Renal Cell Cancer

2021 ◽  
pp. 113-118
Author(s):  
Christopher Weight
Keyword(s):  
Renal Cell Carcinoma ◽  
Overall Survival ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Performance Status ◽  
Cell Cancer ◽  
Interferon Alfa ◽  
Cytoreductive Nephrectomy

This chapter summarizes the findings of a landmark trial of cytoreductive nephrectomy in patients with metastatic renal cell carcinoma performed in the interferon era. All enrolled patients had a good performance status. It found overall survival extended by about 3 months in the cytoreductive-nephrectomy-plus-interferon arm versus the interferon-only arm.

scholarly journals WITHDRAWN: Hereditary leiomyomatosis renal cell carcinoma: A rare case report

2020 ◽  
Vol 33 ◽  
pp. 101045
Author(s):  
Dalin Feng ◽  
Xiaoli Diao ◽  
Mingshuai Wang ◽  
Xiaodong Zhang ◽  
Jianwen Wang
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Rare Case ◽  
Rare Case Report ◽  
Hereditary Leiomyomatosis

scholarly journals The renal cell cancer database Sweden (RCCBaSe) – a new register-based resource for renal cell carcinoma research

2020 ◽  
Vol 54 (3) ◽  
pp. 235-240
Author(s):  
Anna Landberg ◽  
Per Lindblad ◽  
Ulrika Harmenberg ◽  
Sven Lundstam ◽  
Börje Ljungberg ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Cell Cancer
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