Choroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjects

2014 ◽  
Vol 35 (3) ◽  
pp. 403-410 ◽  
Author(s):  
Ibrahim Tuncer ◽  
Eyyup Karahan ◽  
Mehmet Ozgur Zengin ◽  
Eray Atalay ◽  
Nihat Polat
2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Ya Qi ◽  
Li Li ◽  
Fengju Zhang

Purpose. To investigate macular choroidal thickness (CT), topographical variation, and associations between subfoveal choroidal thickness (SFCT) and age, gender, spherical equivalent (SE), and axial length (AL) in Chinese healthy mild and moderate myopia children aged 8 to 11 years. Methods. One hundred twenty eyes from 120 healthy children were studied. Children were divided into mild and moderate myopia groups. AL and CT were evaluated. CTs were measured at the fovea, and 1 mm, 2 mm, and 3 mm nasal, temporal, superior, and inferior to the fovea. Results. SFCT was 252.80 ± 46.95 µm in the whole population. AL was shorter in the mild myopia group (24.18 ± 0.69 mm) than in the moderate myopia group (24.97 ± 0.68 mm, P<0.001), and SFCT was thicker in the mild myopia group (262.00 ± 40.57 µm) than in the moderate myopia group (236.00 ± 55.08 µm, P=0.005). The topographical variation was similar in refraction groups. CTs nasal to the fovea thinned gradually and were all significantly thinner than SFCT. CTs in the other three directions gradually thickened and peaked at locations of 2 mm to the fovea. Then, CTs thinned at 3 mm to the fovea. The thickest choroid is located temporal to the fovea. There were significant negative correlations between AL and SFCT in the mild myopia group and the whole population. No other correlations were found. Conclusions. The topographical variations of choroidal thickness were similar in mild and moderate myopia groups with the thickest locations temporal to the fovea. SFCT was relatively stable in children in narrow range of age and refractive error.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Christiane Al-Haddad ◽  
Lama El Chaar ◽  
Rafic Antonios ◽  
Mays El-Dairi ◽  
Baha’ Noureddin

Objective.To report interocular differences in choroidal thickness in children using spectral domain optical coherence tomography (SD-OCT) and correlate findings with biometric data.Methods.This observational cross-sectional study included 91 (182 eyes) healthy children aged 6 to 17 years with no ocular abnormality except refractive error. After a comprehensive eye exam and axial length measurement, high definition macular scans were performed using SD-OCT. Two observers manually measured the choroidal thickness at the foveal center and at 1500 µm nasally, temporally, inferiorly, and superiorly. Interocular differences were computed; correlations with age, gender, refractive error, and axial length were performed.Results.Mean age was 10.40 ± 3.17 years; mean axial length and refractive error values were similar between fellow eyes. There was excellent correlation between the two observers’ measurements. No significant interocular differences were observed at any location. There was only a trend for right eyes to have higher values in all thicknesses, except the superior thickness. Most of the choroidal thickness measurements correlated positively with spherical equivalent but not with axial length, age, or gender.Conclusion.Choroidal thickness measurements in children as performed using SD-OCT revealed a high level of interobserver agreement and consistent interocular symmetry. Values correlated positively with spherical equivalent refraction.


2020 ◽  
Vol 1 (4) ◽  
pp. 256-261
Author(s):  
Ying Zhou ◽  
◽  
Er-Teng Jia ◽  

This article summarized the choroidal thickness systematically and followed by relevant findings which describes the influencing factors of the choroidal thickness, the changes of the choroidal thickness in ophthalmic diseases and the relationship between the blood flow and the choroidal thickness detailedly. Choroidal thickness is affected by many factors, such as age, gender, intraocular pressure, refractive error, axial length, systolic blood pressure, daily rhythm, body position, smoking history, etc., and choroid is significantly correlated with many ophthalmic diseases. Choroidal thickness is of great importance in the diagnosis and treatment of ophthalmic diseases.


2021 ◽  
pp. 112067212110080
Author(s):  
Masato Kakisu ◽  
Takayuki Baba ◽  
Takehito Iwase ◽  
Hirotaka Yokouchi ◽  
Shuichi Yamamoto

Purpose: To determine whether there is a significant correlation between the retinal sensitivity and the integrity of the ellipsoid zone (EZ) of the photoreceptors in eyes with myopic chorioretinal atrophy (CRA). We also determined the significance of the correlation between the retinal sensitivity and the retinal and choroidal thicknesses. Methods: The medical records of 10 eyes of six subjects with myopic CRA were reviewed. The integrity of the EZ was determined in the spectral-domain optical coherence tomographic (OCT) images at 37 points of six scans corresponding to the locations where the retinal sensitivities were measured by MP-3 microperimetry. The mesopic retinal sensitivities were determined within the central 16°. The significance of the correlations between the integrity of the EZ and the mesopic retinal sensitivities was determined. The relationships between the retinal and choroidal thickness and the retinal sensitivity were also determined. Results: The average age of the patients was 70.0 ± 6.7 years, and the average axial length of the eye was 29.2 mm. The mesopic sensitivities at the points where the EZ was present were significantly higher than those where the EZ was absent ( p < 0.01). The mesopic sensitivity was significantly correlated with the retinal thickness ( p < 0.01, r = 0.30) and the choroidal thickness ( p < 0.01, r = 0.23). Conclusions: The significant correlation between the mesopic retinal sensitivity and the integrity of the EZ indicates that the mesopic sensitivities can be used to assess the integrity of the photoreceptors in eyes with myopic CRA.


2014 ◽  
Vol 158 (3) ◽  
pp. 574-583.e1 ◽  
Author(s):  
Ana Sanchez-Cano ◽  
Elvira Orduna ◽  
Francisco Segura ◽  
Carmen Lopez ◽  
Nicolás Cuenca ◽  
...  

2007 ◽  
Vol 17 (4) ◽  
pp. 515-520 ◽  
Author(s):  
B.J. Kaluzny

Purpose To investigate changes of crystalline lens position during accommodation in children with emmetropia, myopia, and hyperopia. Methods A total of 188 children (372 eyes) from 4 to 19 years old (mean age 11.3±4.43) with cycloplegic refractive error within a range +9.00 D to −9.00 D were enrolled. After a general ophthalmic examination, ultrasound biometry was performed, with the eye at a maximal accommodative effort. Cycloplegia was induced by triple installation of 1% tropicamide drops and 30 minutes later the biometric examination was repeated. Results In emmetropic eyes in the process of accommodation, the anterior pole of the crystalline lens moved forward by 0.144±0.14 mm (p ≤ 0.001); the position of the posterior pole did not change. In myopic eyes, the anterior pole moved forward by 0.071±0.13 mm (p≤0.001) and the posterior pole moved backward by 0.039±0.10 mm (p=0.003). In hyperopic eyes, the whole lens translocated anteriorly: anterior pole moved forward by 0.242±0.16 mm (p≤ 0.001) and posterior pole moved forward by 0.036±0.09 mm (p≤0.001). Differences among emmetropia, myopia, and hyperopia were statistically significant. Forward movement of the posterior pole correlated with a low axial length of the eye, and also with plus refractive error and with a smaller accommodative increase of lens thickness. Conclusions In children, accommodative changes of the crystalline lens position depend on refractive status.


2016 ◽  
Vol 27 (3) ◽  
pp. 331-335 ◽  
Author(s):  
Isil Kurultay-Ersan ◽  
Sinan Emre

Purpose To evaluate the alterations in mean central choroidal, central macular, and disk retinal nerve fiber layer (RNFL) thickness measured by optical coherence tomography (OCT) during Valsalva maneuver among patients with high refractive errors. Methods A total of 60 high myopic (≥-6.0 D) and 50 high hyperopic (≥ + 3.0 D) eyes of 58 patients aged 19-65 years with visual acuity of 20/20 and without any ophthalmologic or systemic diseases were evaluated by OCT before and after the Valsalva maneuver. The choroidal thickness was measured with enhanced depth imaging OCT method. Central macular thickness, disk RNFL thickness, and axial length were also assessed. Results Mean choroidal thickness increased significantly from 275.0 ± 27.2 μm at rest to 279.8 ± 31.6 μm after Valsalva maneuver in high myopic patients, and from 308.2 ± 27.3 μm to 313.6 ± 28.5 μm in high hyperopic patients (p<0.01 for each). A significant negative correlation of the choroidal thickness was noted with axial length (r = -0.509, p<0.01) and age (r = -0.224, p = 0.01) in the overall study population. Mean central macular thickness was 242.9 ± 44.4 μm and 254.0 ± 22.8 μm, while mean disk RNFL thickness was 81.6 ± 12.4 μm and 98.4 ± 13.3 μm in high myopic and hyperopic patients, respectively. Valsalva maneuver was not associated with significant change in central macular or disk RNFL thickness. Conclusions Significant association of Valsalva maneuver with an increase in choroidal thickness was noted among patients with high degree of myopia and hyperopia. Our findings emphasize the likelihood of increase in choroidal volume due to venous distension to be responsible for the increase observed in choroidal thickness after Valsalva maneuver.


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