white adults
Recently Published Documents


TOTAL DOCUMENTS

422
(FIVE YEARS 116)

H-INDEX

49
(FIVE YEARS 3)

Author(s):  
Kevin Heffernan ◽  
Lee Stoner ◽  
Michelle L. Meyer ◽  
Adam Keifer ◽  
Lauren Bates ◽  
...  

Introduction: Aortic stiffness offers important insight into vascular aging and cardiovascular disease (CVD) risk. The referent measure of aortic stiffness is carotid-femoral pulse wave velocity (cfPWV). cfPWV can be estimated (ePWV) from age and mean arterial pressure. Few studies have directly compared the association of ePWV to measured cfPWV, particularly in non-White adults. Moreover, whether ePWV and cfPWV correlate similarly with CVD risk remains unexplored. Aim: (1) To estimate the strength of the agreement between ePWV and cfPWV in both Black and White older adults; and (2) to compare the associations of ePWV and cfPWV with CVD risk factors and determine whether these associations were consistent across races. Methods and Results: We evaluated 4478 [75.2 (SD 5.0) years] Black and White older adults in the Atherosclerosis Risk in Communities (ARIC) Study. cfPWV was measured using an automated pulse waveform analyzer. ePWV was derived from an equation based on age and mean arterial pressure. Association and agreement between the two measurements were determined using Pearson’s correlation coefficient (r), standard error of estimate (SEE), and Bland-Altman analysis. Associations between traditional risk factors with ePWV and cfPWV were evaluated using linear mixed regression models. We observed weak correlations between ePWV and cfPWV within White adults (r = 0.36) and Black adults (r = 0.31). The mean bias for Bland-Altman analysis was low at -0.17 m/s (95%CI: -0.25 to -0.09). However, the inspection of the Bland-Altman plots indicated systematic bias (P < 0.001), which was consistent across race strata. The SEE, or typical absolute error, was 2.8 m/s suggesting high variability across measures. In models adjusted for sex, prevalent diabetes, the number of prevalent cardiovascular diseases, and medication count, both cfPWV and ePWV were positively associated with heart rate, triglycerides, and fasting glucose, and negatively associated with body mass index (BMI) and smoking status in White adults (P < 0.05). cfPWV and ePWV were not associated with heart rate, triglycerides, and fasting glucose in Black adults, while both measures were negatively associated with BMI in Black adults. Conclusions: Findings suggest a weak association between ePWV and cfPWV in older White and Black adults from ARIC. There were similar weak associations between CVD risk factors with ePWV and cfPWV in White adults with subtle differences in associations in Black adults. One sentence summary: Estimated pulse wave velocity is weakly associated with measured carotid-femoral pulse wave velocity in older Black and White adults in ARIC.


Author(s):  
Morgan Elizabeth Ellithorpe ◽  
Bruno Takahashi ◽  
Geri Alumit Zeldes ◽  
Elizabeth Dorrance-Hall ◽  
Manuel Chavez ◽  
...  

2021 ◽  
Author(s):  
Stephen L. Morgan

The General Social Survey (GSS) shows that many self-identified white adults continue to hold racial attitudes that can be regarded, collectively, as a persistent social problem. Similar to findings from the analysis of electoral surveys, the GSS also shows that these racial attitudes have more strongly predicted political behavior since 2012. However, and in contrast to group-identity interpretations of these patterns, the increase in predictive power since 2012 is attributable to a positive development: above and beyond the effects of cohort replacement, support for compensatory interventions to address black-white inequalities has increased substantially, while prejudice and bigotry have decreased slightly. Because these changes have been larger on the political left than on the political right, the attitudes have gained in overall predictive power.


Author(s):  
Nkiru Umekwe ◽  
Ibiye Owei ◽  
Frankie Stentz ◽  
Sam Dagogo-Jack

Abstract Increased circulating fibroblast growth factor (FGF)-21 and sclerostin levels have been reported in patients with type 2 diabetes (T2D). We assessed the association of FGF-21 and sclerostin with adiposity, glycemia and glucoregulatory measures in healthy subjects. We studied 20 normoglycemic Black and White offspring of parents with T2D. Assessments included OGTT, insulin sensitivity (Si-clamp), insulin secretion (HOMA-B), and body fat (DXA). Fasting plasma FGF-21 and sclerostin levels were measured with ELISAs. The participants' mean (+SD) age was 50.4 ± 5.97 yr; BMI 32.5 ± 5.86 kg/m2; fasting plasma glucose (FPG) 96.1 ± 5.21 mg/dl, and 2-hr post-load glucose (2hPG) 116 ± 5.45 mg/dl. FGF-21 levels were similar in Blacks vs. Whites (0.36 ± 0.15 ng/ml vs. 0.39 ± 0.25 ng/ml), men vs. women (0.45 ± 0.14 vs. 0.44 ± 0.07ng/ml), correlated positively with body mass index (BMI) (r=0.23, P=0.05) and waist circumference (r=0.27, P=0.04), and inversely with FPG (r= -0.26, P=0.05). Sclerostin levels also were similar in Blacks (33.5 ± 17.1 pmol/l) vs. Whites (34.2 ± 6.41 pmol/l), men vs. women (35.3 ± 9.01 pmol/l vs. 32.3 ± 15.8 pmol/l), and correlated inversely with FPG (r= - 0.11-0.44) but not adiposity measures. The correlation coefficient between Si-clamp values and FGF-21 levels was -0.31 (P=0.09) compared with 0.04 (P=0.89) for sclerostin levels. FGF-21 and sclerostin levels were not correlated with each other or HOMA-B. Among healthy Black and White subjects, plasma FGF-21 and sclerostin showed differential associations with adiposity but concordant association with FPG levels.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 570-570
Author(s):  
Ronica Rooks ◽  
Allison Leanage

Abstract Little longitudinal research exists on health and working among older racial and ethnic minority adults. Following previous cross-sectional research, we examine the Health, Aging, and Body Composition (HABC) study comparing working vs. not working overtime among older adults. We hypothesize: 1) Black vs. White adults are more likely to work; 2) Black vs. White differences in working are greater among women than men; and 3) Working relates to fewer prevalent health problems than not working. We used gender-stratified descriptive statistics and generalized mixed-effects logistic regression with covariate adjustments to analyze the HABC cohort study, with community-dwelling, well-functioning Black (42%) and White older adults aged 70-79 in year 1 (n=3,069) to year 6 (n=2,091). We found support for all three hypotheses. Black vs. White adults were more likely to work overtime. Women were less likely to work overtime compared to men. White women were less likely to keep working compared to men and Black women. Lastly, older adults with fewer chronic conditions were more likely to continue working. Our study finds racial and gender differences among older adults working overtime. Intersectionality plays a role in older adults’ health and work disparities, leading us to explore the needs and/or benefits of working past retirement in specific groups. Our policy implication is for society to pro-actively invest in older adults’ health and productive activities, which may act as social determinants of health solutions to reduce disparities and growing social safety net program costs.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 261-261
Author(s):  
Bryan James ◽  
Ana Capuano ◽  
Robert Wilson ◽  
Lisa Barnes ◽  
Melissa Lamar

Abstract Negative social stressors (e.g., perceived loneliness and/or social isolation) predict mortality in older adults; less is known about the role of positive social activities. What research does exist focuses on White adults, leaving gaps in knowledge regarding specific activities that may decrease mortality risk in Black adults. We investigated whether self-reported late-life social activity, generally and by type, predicted mortality risk in 768 Black adults (age~73yrs; non-demented at baseline) participating in MARS. Over ~6.5 follow-up years, 25% of participants died (n=192; age-at-death~83yrs). In fully-adjusted Cox models including demographic, health, and relevant psychosocial covariates, mortality risk decreased by 32% (HR=0.68,95%CI=0.49,0.93) in those with higher compared to lower social activity generally, and with higher volunteer-, church- and group-related activities specifically. Engaging in social activity, especially altruistic or faith-based activities, reduces mortality risk in older Blacks regardless of overall health or social stressors pointing toward community-based approaches to increase longevity in this population.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 399-399
Author(s):  
Agus Surachman ◽  
Alexis Santos ◽  
Jonathan Daw ◽  
Lacy Alexander ◽  
Christopher Coe ◽  
...  

Abstract This paper examines the association between educational mobility and age-related decrements in kidney function. Data from the main survey and the Biomarker Project of the Midlife in the United States (MIDUS) Wave 2 and Refresher samples were combined, resulting in 1,861 adults (54.5% female; age 25-84, Mage=53.37) who self-identified as non-Hispanic Black (n=326) and non-Hispanic white (n=1,535). The estimated glomerular filtration rate (eGFR) was based on serum creatinine, calculated using the CKD-EPI formula. Intergenerational educational mobility was based on the comparison between parental education (no high school/HS degree versus HS degree or higher) and participant’s education level (HS degree or lower versus some college versus bachelor’s degree or higher). Results from regression analysis indicated that Black participants in the moderate upward mobility group (parental education = no HS degree, participant’s education = some college) showed significantly steeper age-related decrements in eGFR across adulthood compared to Black adults with higher stable high status (parental education = HS degree or higher, participant’s education = bachelor’s degree or higher), B=-0.70, SE=0.26, p=.008, or white adults with higher stable high status, B= 0.58, SE=0.29, p=.044. A steeper age-related decrement in eGFR is known as a reliable risk factor for chronic kidney disease and cardiovascular disease. These findings support the notion of skin-deep resilience among Black adults who experience upward socioeconomic mobility. We explored multiple psychosocial factors that may explain these findings, including lifetime and daily discrimination, social status and financial strains, and perceived stress and depressive symptoms.


2021 ◽  
Author(s):  
Wei Gao ◽  
Pengfei Dai ◽  
Yuqian Wang ◽  
Yurong Zhang

Abstract Background: Walking impairment, a common health problem among older adults, has been linked to poor vision and mental health. This study aimed to investigate the associations of walking impairment with visual impairment, depression, and cognitive function in older adults. Methods: A total of 1,489 adults aged 60 years and older who had participated in the National Health and Examination Survey (NHANES) 2013-2014 in the United States were included. Multivariate logistic regression models were used to examine the associations of walking impairment with visual impairment, depression, and four subdomains of cognitive function. Sample weights were used to ensure the generalizability of the results.Results: Among all the participants (median age=68 years; 53.7% women), 17.5% reported walking impairment. Walking impairment was significantly associated with visual impairment (adjusted odds ratio [aOR] =2.76; 95% CI: 1.47-5.20) and depression (aOR=4.66; 95% CI: 3.11-6.99). Walking impairment was only associated with the Digit Symbol Substitution (DSST) subdomain of cognitive function in total participants (aOR=0.97; 95% CI: 0.95-0.99), and in non-Hispanic white adults (aOR=0.96; 95% CI: 0.94-0.98). Participants with more than 1 impairment indicators had higher OR of walking impairment (aOR = 3.64, 95% CI =2.46-5.38) than those with 0-1 (reference group) impairment indicator.Conclusions: Walking impairment was associated with visual impairment, depression, and cognitive impairment in the American older adults and also positively associated with the number of impairment indicators. The association between walking impairment and cognitive impairment varied according to race. Evaluations of vision, cognition, and depression should be conducted among the elderly with walking impairment, and that needs of the older adults with biological aspect of their particular race should be provided in the evaluations.


Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1518
Author(s):  
Lin Zhu ◽  
Wei J. Yang ◽  
Cody B. Spence ◽  
Aisha Bhimla ◽  
Grace X. Ma

(1) Background: Despite having consistently lower rates of obesity than other ethnic groups, Asian Americans (AAs) are more likely to be identified as metabolically obese, suggesting an ethnic-specific association between BMI and cardiometabolic outcomes. The goal of this study was to provide an estimate of metabolic syndrome (MetS) prevalence among AAs using national survey data and to compare this rate to that of non-Hispanic Whites (NHWs) over the BMI continuum. (2) Methods: Using the NHANES 2011–2016 data, we computed age-adjusted, gender-specific prevalence of MetS and its individual components for three BMI categories. Furthermore, we conducted multivariate binary logistic regression to examine the risk of MetS in AAs compared to NHWs, controlling for sociodemographic and lifestyle factors. The analysis sample consisted of 2121 AAs and 6318 NHWs. (3) Results: Among AAs, the prevalence of MetS and its components increased with higher BMI levels, with overall prevalence being 5.23% for BMI < 23, 38.23% for BMI of 23–27.4, and 77.68% for BMI ≥ 27.5 in men; and 18.61% for BMI < 23, 47.82% for BMI of 23–27.4, and 67.73% for BMI ≥ 27.5 in women. We also found that for those with a BMI > 23, AAs had a higher predicted risk of MetS than their NHW counterparts of the same BMI level, in both men and women. (4) Conclusions: Our findings support the use of lower BMI ranges for defining overweight and obesity in Asian populations, which would allow for earlier and more appropriate screening for MetS and may better facilitate prevention efforts.


Sign in / Sign up

Export Citation Format

Share Document