scholarly journals Interocular Symmetry in Macular Choroidal Thickness in Children

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Christiane Al-Haddad ◽  
Lama El Chaar ◽  
Rafic Antonios ◽  
Mays El-Dairi ◽  
Baha’ Noureddin
Keyword(s):  
Refractive Error ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Healthy Children ◽  
Spherical Equivalent ◽  
High Definition ◽  
Biometric Data ◽  
Ocular Abnormality ◽  
Thickness Measurements ◽  
Sd Oct

Objective.To report interocular differences in choroidal thickness in children using spectral domain optical coherence tomography (SD-OCT) and correlate findings with biometric data.Methods.This observational cross-sectional study included 91 (182 eyes) healthy children aged 6 to 17 years with no ocular abnormality except refractive error. After a comprehensive eye exam and axial length measurement, high definition macular scans were performed using SD-OCT. Two observers manually measured the choroidal thickness at the foveal center and at 1500 µm nasally, temporally, inferiorly, and superiorly. Interocular differences were computed; correlations with age, gender, refractive error, and axial length were performed.Results.Mean age was 10.40 ± 3.17 years; mean axial length and refractive error values were similar between fellow eyes. There was excellent correlation between the two observers’ measurements. No significant interocular differences were observed at any location. There was only a trend for right eyes to have higher values in all thicknesses, except the superior thickness. Most of the choroidal thickness measurements correlated positively with spherical equivalent but not with axial length, age, or gender.Conclusion.Choroidal thickness measurements in children as performed using SD-OCT revealed a high level of interobserver agreement and consistent interocular symmetry. Values correlated positively with spherical equivalent refraction.

scholarly journals Choroidal Thickness in Chinese Children Aged 8 to 11 Years with Mild and Moderate Myopia

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Ya Qi ◽  
Li Li ◽  
Fengju Zhang
Keyword(s):  
Refractive Error ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Narrow Range ◽  
The Other ◽  
Chinese Children ◽  
Healthy Children ◽  
Spherical Equivalent ◽  
Subfoveal Choroidal Thickness

Purpose. To investigate macular choroidal thickness (CT), topographical variation, and associations between subfoveal choroidal thickness (SFCT) and age, gender, spherical equivalent (SE), and axial length (AL) in Chinese healthy mild and moderate myopia children aged 8 to 11 years. Methods. One hundred twenty eyes from 120 healthy children were studied. Children were divided into mild and moderate myopia groups. AL and CT were evaluated. CTs were measured at the fovea, and 1 mm, 2 mm, and 3 mm nasal, temporal, superior, and inferior to the fovea. Results. SFCT was 252.80 ± 46.95 µm in the whole population. AL was shorter in the mild myopia group (24.18 ± 0.69 mm) than in the moderate myopia group (24.97 ± 0.68 mm, P<0.001), and SFCT was thicker in the mild myopia group (262.00 ± 40.57 µm) than in the moderate myopia group (236.00 ± 55.08 µm, P=0.005). The topographical variation was similar in refraction groups. CTs nasal to the fovea thinned gradually and were all significantly thinner than SFCT. CTs in the other three directions gradually thickened and peaked at locations of 2 mm to the fovea. Then, CTs thinned at 3 mm to the fovea. The thickest choroid is located temporal to the fovea. There were significant negative correlations between AL and SFCT in the mild myopia group and the whole population. No other correlations were found. Conclusions. The topographical variations of choroidal thickness were similar in mild and moderate myopia groups with the thickest locations temporal to the fovea. SFCT was relatively stable in children in narrow range of age and refractive error.

scholarly journals Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

2017 ◽  
Vol 11 (01) ◽  
pp. 1850001
Author(s):  
Inmaculada Bueno-Gimeno ◽  
Enrique España-Gregori ◽  
Andres Gene-Sampedro ◽  
Juan Carlos Ondategui-Parra ◽  
Carlos J. Zapata-Rodriguez
Keyword(s):  
Optic Disc ◽  
Refractive Error ◽  
Axial Length ◽  
Healthy Children ◽  
Spherical Equivalent ◽  
Correct Interpretation ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Master System ◽  
Magnification Effect

Purpose: The aim of this paper was to examine the distribution of macular, retinal nerve fiber layer (RNFL) thickness and optic disc parameters of myopic and hyperopic eyes in comparison with emmetropic control eyes and to investigate their variation according to axial length (AL) and spherical equivalent (SE) in healthy children. Methods: This study included 293 pairs of eyes of 293 children (145 boys and 148 girls), ranging in age from 6 to 17 years. Subjects were divided according to SE in control (emmetropia, 99 children), myopia (100 children) and hyperopia (94 children) groups and according to axial AL in 68 short ([Formula: see text]22.00[Formula: see text]mm, 68), medium (from [Formula: see text]22.00[Formula: see text]mm to 25.00[Formula: see text]mm, 189) and long eyes ([Formula: see text]25.00[Formula: see text]mm, 36). Macular parameters, RNFL thickness and optic disc morphology were assessed by the CirrusTM HD-OCT. AL was measured using the IOL-Master system. Littmann’s formula was used for calculating the corrected AL-related ocular magnification. Results: Mean age ([Formula: see text][Formula: see text]SD) was 10.84[Formula: see text][Formula: see text][Formula: see text]3.05 years; mean ([Formula: see text][Formula: see text]SD) SE was [Formula: see text]0.14[Formula: see text][Formula: see text][Formula: see text]0.51 D (range from [Formula: see text]8.75 to [Formula: see text]8.25 D) and mean AL ([Formula: see text][Formula: see text]SD) was 23.12[Formula: see text][Formula: see text][Formula: see text]1.49. Average RNFL thickness, average macular thickness and macular volume decreased as AL and myopia increased. No correlations between AL/SE and optic disc parameters were found after correcting for magnification effect. Conclusions: AL and refractive error affect measurements of macular and RNFL thickness in healthy children. To make a correct interpretation of OCT measurements, ocular magnification effect should be taken into account by clinicians or OCT manufacturers.

scholarly journals A calculator proposal for estimating refractive error after 3 years using the onset biometric values in primary school children: a cohort study

2021 ◽  
Author(s):  
Feride Tuncer Orhan ◽  
Haluk Huseyin Gürsoy
Keyword(s):  
Primary School ◽  
Anterior Chamber ◽  
Refractive Error ◽  
Axial Length ◽  
Anterior Chamber Depth ◽  
Primary School Children ◽  
Optical Parameters ◽  
Spherical Equivalent ◽  
Final Data ◽  
The Mean

Aim To evaluate consecutive measurements of the biometric parameters, age, and refraction error in a Turkish population at primary school age. Materials and Methods A total of 197 children aged between 7-12 years were included. The data of three consecutive measurements of children, who were examined at least once a year for three years using both cycloplegic auto-refractometry and optical biometry, were used in this retrospective study. Spherical equivalent <-0.50D was considered to be myopic; >+0.75D was considered to be hypermetropic. Age, gender, body mass index, spherical equivalent, axial length, anterior chamber depth, central corneal thickness, keratometry, and lens thickness were analyzed. The onset data obtained in 2013 whereas, the final data were from 2015. Logistic and Cox regression analyses were performed (p<0.05). Results The mean of the onset and the final spherical equivalents were 0.19D (0.56), and 0.08D (0.80), respectively. The myopia prevalence was increased among refractive errors in observation periods (univariable analysis p=0.029; multivariable analysis p=0.017). The onset axial length (HR:4.55, 95%CI:2.87-7.24, p<0.001), keratometry (HR:2.04, 95%CI:1.55-2.67, p<0.001) and age (HR:0.73, 95%CI: 0.57-0.92, p=0.009) correlated myopia progression. To calculate the estimated spherical equivalent, the onset data were included in the logistic regression model. The onset data of spherical equivalent (β=0.916, p<0.001), axial length (β=-0.451, p<0.001), anterior chamber depth (β=0.430, p=0.005) and keratometry (β=-0.172, p<0.001) were found to be significantly associated with the mean SE at the final data. Conclusions To calculate the estimated spherical equivalent following three years, an equation was proposed. The estimated refractive error of children can be calculated by using the proposed equation with the associated onset optical parameters.

Choroidal thickness evaluation in paediatric patients with adenotonsillar hypertrophy

2017 ◽  
Vol 131 (9) ◽  
pp. 768-772
Author(s):  
A Yenigun ◽  
A Elbay ◽  
A M Hafiz ◽  
O Ozturan
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Healthy Children ◽  
Depth Imaging ◽  
Adenotonsillar Hypertrophy ◽  
Paediatric Patients ◽  
Healthy Control ◽  
Imaging Optical Coherence Tomography ◽  
Thickness Measurements

AbstractObjective:To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy.Methods:The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken.Results:In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048).Conclusion:There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.

scholarly journals Comparison of Choroidal Thickness Measurements between Spectral-domain Optical Coherence Tomography and Swept-source Optical Coherence Tomography in Children

2021 ◽  
Author(s):  
Chun On Lee ◽  
Xiujuan Zhang ◽  
Shumin Tang ◽  
Li Jia Chen ◽  
Carol Cheung ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Correlation Coefficient ◽  
Choroidal Thickness ◽  
Relative Difference ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Normal Children ◽  
Swept Source ◽  
Thickness Measurements ◽  
Sd Oct

Abstract PURPOSE: Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domain optical coherence tomography (SD-OCT) and swept-source optical coherence tomography (SS-OCT) in healthy pediatric eyes.METHODS: Children from the population–based Hong Kong Children Eye Study were recruited. Choroidal thickness was measured by both devices. Intra-class correlation coefficient (ICC) was used to compare the measurements.RESULTS: A total of 114 children with mean age of 7.38±0.82 years were included. The central foveal choroidal thickness (CFCT) measured by SD-OCT and SS-OCT was 273.24±54.29μm and 251.84±47.12μm respectively. Inter-device correlation coefficient was 0.840 (95%CI: 0.616-0.918). However, choroidal thickness obtained by SD-OCT was significantly thicker than that measured by SS-OCT with a mean difference of 21.40±33.13μm (P<0.001). Bland-Altman limit of agreement on the relative difference scale for SD-OCT/SS-OCT was 86.33μm. Validated conversion equation for translating SD-OCT CFCT measurement into SS-OCT was SS-OCT = 35.261 + 0.810 x SD-OCT. CONCLUSIONS: ICC shows an acceptable agreement between SD-OCT and SS-OCT, however, there was a significant inter-device difference of choroidal thickness measurements in normal children eyes. Therefore, the measurements are not interchangeable.

scholarly journals Validation of Macular Choroidal Thickness Measurements from Automated SD-OCT Image Segmentation

2016 ◽  
Vol 93 (11) ◽  
pp. 1387-1398 ◽  
Author(s):  
Michael D. Twa ◽  
Krystal L. Schulle ◽  
Stephanie J. Chiu ◽  
Sina Farsiu ◽  
David A. Berntsen
Keyword(s):  
Image Segmentation ◽  
Choroidal Thickness ◽  
Thickness Measurements ◽  
Oct Image ◽  
Sd Oct

Choroidal thickness in relation to sex, age, refractive error, and axial length in healthy Turkish subjects

2014 ◽  
Vol 35 (3) ◽  
pp. 403-410 ◽  
Author(s):  
Ibrahim Tuncer ◽  
Eyyup Karahan ◽  
Mehmet Ozgur Zengin ◽  
Eray Atalay ◽  
Nihat Polat
Keyword(s):  
Refractive Error ◽  
Axial Length ◽  
Choroidal Thickness

scholarly journals Pachychoroid Pigment Epitheliopathy and Choroidal Thickness Changes in Coeliac Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Selim Bolukbasi ◽  
Burak Erden ◽  
Akin Cakir ◽  
Alper Halil Bayat ◽  
Mustafa Nuri Elcioglu ◽  
...  
Keyword(s):  
Coeliac Disease ◽  
Choroidal Thickness ◽  
Healthy Controls ◽  
Prospective Comparative Study ◽  
The Mean ◽  
Thickness Measurements ◽  
Choroidal Vessels ◽  
Pachychoroid Pigment Epitheliopathy ◽  
Fellow Eyes ◽  
Sd Oct

Purpose. To evaluate choroidal thickness in patients with coeliac disease (CD) using spectral domain optical coherence tomography (SD-OCT) and to compare the results to normal eyes. Methods. Seventy patients with CD and 70 healthy controls were included in this prospective, comparative study. All participants underwent a complete ophthalmologic evaluation and SD-OCT. Subfoveal, nasal (nasal distance to fovea 500 μm, 1000 μm, and 1500 μm), and temporal (temporal distance to fovea 500 μm, 1000 μm, and 1500 μm) choroidal thickness measurements were performed using SD-OCT. Results. There were no significant differences in sex, ages, and axial lengths between the groups (p=1.0, p=0.601, p=0.314, respectively). The mean choroidal thickness measurements at all predefined measurement point areas were higher in the coeliac group than in the healthy controls (p<0.001). Of all patients with coeliac disease (70 eyes of 70 patients), 64 eyes (84.2%) had uncomplicated pachychoroid (UCP), one eye had pachychoroid pigment epitheliopathy (PPE), and five eyes in the UCP group had PPE in fellow eyes. Conclusion. It is probable that systemic inflammation in coeliac patients causes the enlargement of choroidal vessels and increasing choroidal thickness. PPE, which is believed to be the precursor of central serous chorioretinopathy, can be observed in coeliac patients.

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