A controlled release system of superoxide dismutase by electrospun fiber and its antioxidant activity in vitro

2009 ◽  
Vol 21 (2) ◽  
pp. 609-614 ◽  
Author(s):  
Ping Chen ◽  
Yu-jun Sun ◽  
Zi-chun Zhu ◽  
Rui-xia Wang ◽  
Xiu-dong Shi ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Controlled Release ◽  
Electrospun Fiber ◽  
Release System ◽  
Controlled Release System

A controlled release system of titanocene dichloride by electrospun fiber and its antitumor activity in vitro

2010 ◽  
Vol 76 (3) ◽  
pp. 413-420 ◽  
Author(s):  
Ping Chen ◽  
Qing-Sheng Wu ◽  
Ya-Ping Ding ◽  
Maoquan Chu ◽  
Zheng-Ming Huang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Antitumor Activity ◽  
Electrospun Fiber ◽  
Titanocene Dichloride ◽  
Release System ◽  
Controlled Release System

In vitro analysis of a novel controlled release system designed for intratympanic administration of N-acetylcysteine: a preliminary report

2015 ◽  
Vol 36 (6) ◽  
pp. 786-793 ◽  
Author(s):  
Zafer Ciftci ◽  
Mahmut Deniz ◽  
Ibrahim Yilmaz ◽  
Halide Gunes Ciftci ◽  
Duygu Yasar Sirin ◽  
...  
Keyword(s):  
Controlled Release ◽  
Preliminary Report ◽  
Release System ◽  
Controlled Release System ◽  
Vitro Analysis ◽  
In Vitro Analysis

scholarly journals A Cyclodextrin-Based Controlled Release System in the Simulation of In Vitro Small Intestine

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1212
Author(s):  
Danni Zheng ◽  
Liuxi Xia ◽  
Hangyan Ji ◽  
Zhengyu Jin ◽  
Yuxiang Bai
Keyword(s):  
Complex System ◽  
Small Intestine ◽  
Controlled Release ◽  
Glucose Production ◽  
Scanning Calorimetry ◽  
Release System ◽  
In Vitro Simulation ◽  
Controlled Release System ◽  
Enteric Coated

A novel cyclodextrin (CD)-based controlled release system was developed in the small intestine to control the rate of drug release, on the premise of enteric-coated tablets. The system was designed based on the enzymes exogenous β-cyclodextrin glycosyltransferase (β-CGTase) and endogenous maltase-glucoamylase (MG), wherein MG is secreted in the small intestine and substituted by a congenerous amyloglucosidase (AG). The vanillin-/curcumin-β-CD complexes were prepared and detected by Fourier transform infrared (FT-IR), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC), and host CD degradation was measured based on the glucose yield. The combination of β-CGTase and AG was also functional in the CD complex system. The variations in the concentrations of added β-CGTase, with AG constantly in excess, could effectively alter the rate of host CD degradation and guest release by monitoring glucose production and color disappearance, thus, demonstrating that guest release in the CD complex system could be precisely controlled by changing the amount of β-CGTase used. Thus, the in vitro simulation of the system indicated that a novel controlled release system, based on endogenous MG, could be established in the small intestine. The CD-based controlled release system can be potentially applied in drug delivery and absorption in the small intestine.

In vitro investigation of lipid implants as a controlled release system for interleukin-18

2006 ◽  
Vol 314 (2) ◽  
pp. 145-152 ◽  
Author(s):  
S. Koennings ◽  
E. Garcion ◽  
N. Faisant ◽  
P. Menei ◽  
J.P. Benoit ◽  
...  
Keyword(s):  
Controlled Release ◽  
Interleukin 18 ◽  
Release System ◽  
In Vitro Investigation ◽  
Controlled Release System
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