scholarly journals Toward the identification and the targeting of key players of the mitochondrial unfolded protein response (UPRmt) in cancer

2017 ◽  
Author(s):  
Doris Germain
Keyword(s):  
Unfolded Protein Response ◽  
Unfolded Protein ◽  
Key Players ◽  
Protein Response ◽  
Mitochondrial Unfolded Protein Response

scholarly journals At the heart of mitochondrial quality control: many roads to the top

2021 ◽  
Author(s):  
Roberta A. Gottlieb ◽  
Honit Piplani ◽  
Jon Sin ◽  
Savannah Sawaged ◽  
Syed M. Hamid ◽  
...  
Keyword(s):  
Quality Control ◽  
Unfolded Protein Response ◽  
Mitochondrial Biogenesis ◽  
Mitochondrial Dynamics ◽  
Mitochondrial Quality Control ◽  
Unfolded Protein ◽  
Selective Elimination ◽  
Protein Response ◽  
Mitochondrial Unfolded Protein Response

AbstractMitochondrial quality control depends upon selective elimination of damaged mitochondria, replacement by mitochondrial biogenesis, redistribution of mitochondrial components across the network by fusion, and segregation of damaged mitochondria by fission prior to mitophagy. In this review, we focus on mitochondrial dynamics (fusion/fission), mitophagy, and other mechanisms supporting mitochondrial quality control including maintenance of mtDNA and the mitochondrial unfolded protein response, particularly in the context of the heart.

scholarly journals The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling

Cell ◽  
2018 ◽  
Vol 174 (4) ◽  
pp. 870-883.e17 ◽  
Author(s):  
Qian Zhang ◽  
Xueying Wu ◽  
Peng Chen ◽  
Limeng Liu ◽  
Nan Xin ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Unfolded Protein Response ◽  
Unfolded Protein ◽  
Protein Response ◽  
Mitochondrial Unfolded Protein Response

scholarly journals Impairment of mitochondrial unfolded protein response contribute to resistance declination of H 2 O 2 ‐induced injury in senescent MRC‐5 cell model

2019 ◽  
Vol 36 (2) ◽  
pp. 89-97
Author(s):  
Tzu‐Ying Lee ◽  
Li‐Ju Huang ◽  
Huei‐Ping Dong ◽  
Yoshioka Tohru ◽  
Bo‐Hong Liu ◽  
...  
Keyword(s):  
Unfolded Protein Response ◽  
Cell Model ◽  
Unfolded Protein ◽  
Protein Response ◽  
Mitochondrial Unfolded Protein Response
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