Basic Amino Acids Within the Juxtamembrane Domain of the Epidermal Growth Factor Receptor Regulate Receptor Dimerization and Auto-phosphorylation

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Juxtamembrane Domain ◽

Receptor Dimerization ◽

Basic Amino Acids ◽

The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis

BMC Biochemistry ◽

10.1186/1471-2091-15-13 ◽

2014 ◽

Vol 15 (1) ◽

pp. 13 ◽

Cited By ~ 7

Author(s):

Xiudan Zheng ◽

Jing Zhang ◽

Kan Liao

Keyword(s):

Amino Acids ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phosphatidic Acid ◽

Coiled Coil ◽

Growth Factor Receptor ◽

Basic Amino Acids ◽

Coiled Coil Domain ◽

Inhibiting Epidermal Growth Factor Receptor Dimerization and Signaling Through Targeted Delivery of a Juxtamembrane Domain Peptide Mimic

ACS Chemical Biology ◽

10.1021/acschembio.8b00555 ◽

2018 ◽

Vol 13 (9) ◽

pp. 2623-2632 ◽

Cited By ~ 7

Author(s):

Janessa Gerhart ◽

Anastasia F. Thévenin ◽

Elizabeth Bloch ◽

Kelly E. King ◽

Damien Thévenin

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Targeted Delivery ◽

Growth Factor Receptor ◽

Juxtamembrane Domain ◽

Receptor Dimerization ◽

Peptide Mimic ◽

Epidermal Growth ◽

Domain Peptide

Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells.

10.1016/s0021-9258(18)47026-3 ◽

1994 ◽

Vol 269 (44) ◽

pp. 27595-27602

Author(s):

Z Fan ◽

Y Lu ◽

X Wu ◽

J Mendelsohn

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Squamous Carcinoma ◽

Carcinoma Cells ◽

Receptor Dimerization ◽

Squamous Carcinoma Cells ◽

Unliganded Epidermal Growth Factor Receptor Dimerization Induced by Direct Interaction of Quinazolines with the ATP Binding Site

10.1074/jbc.272.37.23247 ◽

1997 ◽

Vol 272 (37) ◽

pp. 23247-23254 ◽

Cited By ~ 101

Author(s):

Carlos L. Arteaga ◽

Timothy T. Ramsey ◽

Laura K. Shawver ◽

Cheryl A. Guyer

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Binding Site ◽

Growth Factor Receptor ◽

Direct Interaction ◽

Atp Binding ◽

Receptor Dimerization ◽

Atp Binding Site ◽

Analysis of Epidermal Growth Factor Receptor Dimerization by BS3 Cross-Linking

Methods in Molecular Biology - Receptor Tyrosine Kinases ◽

10.1007/978-1-4939-1789-1_3 ◽

2014 ◽

pp. 25-34 ◽

Cited By ~ 7

Author(s):

Harmony F. Turk ◽

Robert S. Chapkin

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Cross Linking ◽

Receptor Dimerization ◽

The Cytoplasmic Juxtamembrane Domain of the Epidermal Growth Factor Receptor Contains a Novel Autonomous Basolateral Sorting Determinant

10.1074/jbc.272.52.32901 ◽

1997 ◽

Vol 272 (52) ◽

pp. 32901-32909 ◽

Cited By ~ 47

Author(s):

Michael E. Hobert ◽

Song J. Kil ◽

M. Edward Medof ◽

Cathleen R. Carlin

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Juxtamembrane Domain ◽

Plakophilin-2 Promotes Tumor Development by Enhancing Ligand-Dependent and -Independent Epidermal Growth Factor Receptor Dimerization and Activation

Molecular and Cellular Biology ◽

10.1128/mcb.00758-14 ◽

2014 ◽

Vol 34 (20) ◽

pp. 3843-3854 ◽

Cited By ~ 20

Author(s):

K.-i. Arimoto ◽

C. Burkart ◽

M. Yan ◽

D. Ran ◽

S. Weng ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Tumor Development ◽

Growth Factor Receptor ◽

Receptor Dimerization ◽

Plakophilin 2 ◽

Epidermal growth factor receptor dimerization status determines response to HER-kinase targeted therapies in keratinocytes

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3062 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3062-3062

Author(s):

I. Laux ◽

A. Jain ◽

C. A. Tindell ◽

D. B. Agus

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Targeted Therapies ◽

Growth Factor Receptor ◽

Receptor Dimerization ◽

A Structural Model for the Membrane-bound Form of the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

10.1074/jbc.m502698200 ◽

2005 ◽

Vol 280 (25) ◽

pp. 24043-24052 ◽

Cited By ~ 30

Author(s):

Kiattawee Choowongkomon ◽

Cathleen R. Carlin ◽

Frank D. Sönnichsen

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Structural Model ◽

Growth Factor Receptor ◽

Juxtamembrane Domain ◽

Epidermal Growth ◽

Membrane Bound

Epidermal growth factor receptor dimerization monitored in live cells

Nature Biotechnology ◽

10.1038/72686 ◽

2000 ◽

Vol 18 (2) ◽

pp. 218-222 ◽

Cited By ~ 67

Author(s):

Bruce T. Blakely ◽

Fabio M. V. Rossi ◽

Bonnie Tillotson ◽

Michelle Palmer ◽

Angeles Estelles ◽

...

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Live Cells ◽

Receptor Dimerization ◽