Overexpression of a novel gene Aokap2 affects the growth and kojic acid production in Aspergillus oryzae

2022 ◽  
Author(s):  
Yuzhen Li ◽  
Huanxin Zhang ◽  
Ziming Chen ◽  
Junxia Fan ◽  
Tianming Chen ◽  
...  
Keyword(s):  
Aspergillus Oryzae ◽  
Acid Production ◽  
Kojic Acid ◽  
Novel Gene ◽  
Kojic Acid Production

Improvement of kojic acid production in Aspergillus oryzae B008 mutant strain and its uses in fermentation of concentrated corn stalk hydrolysate

2013 ◽  
Vol 37 (6) ◽  
pp. 1095-1103 ◽  
Author(s):  
Shoubao Yan ◽  
Huijuan Tang ◽  
Shunchang Wang ◽  
Liangting Xu ◽  
Hongyan Liu ◽  
...  
Keyword(s):  
Mutant Strain ◽  
Aspergillus Oryzae ◽  
Acid Production ◽  
Kojic Acid ◽  
Corn Stalk ◽  
Kojic Acid Production

scholarly journals Aspergillus oryzae-based cell factory for direct kojic acid production from cellulose

2014 ◽  
Vol 13 (1) ◽  
pp. 71 ◽  
Author(s):  
Ryosuke Yamada ◽  
Toshihide Yoshie ◽  
Satoshi Wakai ◽  
Nanami Asai-Nakashima ◽  
Fumiyoshi Okazaki ◽  
...  
Keyword(s):  
Aspergillus Oryzae ◽  
Acid Production ◽  
Kojic Acid ◽  
Cell Factory ◽  
Kojic Acid Production

scholarly journals OPTIMIZATION OF ASPERGILLUS ORYZAE FERMENTATION CONDITIONS FOR KOJIC ACID PRODUCTION

2018 ◽  
Vol 10 (1) ◽  
pp. 316 ◽  
Author(s):  
Adnina Fitra Azzahra ◽  
Dyah Karina Puspita Sukarna ◽  
Herman Suryadi
Keyword(s):  
Aspergillus Oryzae ◽  
Yeast Extract ◽  
Acid Production ◽  
Kojic Acid ◽  
Nitrogen Sources ◽  
Carbon And Nitrogen Sources ◽  
Fermentation Conditions ◽  
Carbon And Nitrogen ◽  
Aeration Condition ◽  
Kojic Acid Production

Objective: The objective of this study is to obtain the optimal fermentation conditions for Aspergillus oryzae by gradually optimizing the medium andfermentation conditions.Methods: Fermentation condition were optimized by varying carbon and nitrogen sources, pH medium, temperature, and aeration condition. Levelsof kojic acid were determined using thin-layer chromatography-densitometry with an ultraviolet detector at a wavelength of 318 nm.Results: A combination of sucrose and yeast extract was chosen as the best source of carbon and nitrogen, respectively, from nine medium variations,producing 1.5425 g/L kojic acid. The optimum acidity of the medium was at pH 4.5, producing 1.7127 g/L of kojic acid, compared with pH 3.5 and5.5. Compared with fermentation at room temperature, fermentation at 35°C yielded greater kojic acid production. The best aeration condition was100 mL medium in 250 mL flask that produced the most kojic acid (1.6472 g/L).Conclusion: The optimal medium for fermentation of kojic acid using A. oryzae uses sucrose and yeast extract as carbon and nitrogen sources,respectively, at pH 4.5. The optimal aeration and incubation conditions were used, a volume of 100 mL in a 250 mL conical flask, incubated at 35°C,obtaining the highest yield value of 0.0370 g/g.

scholarly journals Effect of culture conditions and medium compositions on kojic acid production by Aspergillus oryzae ATCC 10124

2019 ◽  
Vol 346 ◽  
pp. 012047 ◽  
Author(s):  
A Promsang ◽  
V Rungsardthong ◽  
B Thumthanaruk ◽  
C Puttanlek ◽  
D Uttapap ◽  
...  
Keyword(s):  
Aspergillus Oryzae ◽  
Acid Production ◽  
Kojic Acid ◽  
Culture Conditions ◽  
Kojic Acid Production

Combining induced mutation and protoplasting for strain improvement of Aspergillus oryzae for kojic acid production

2004 ◽  
Vol 26 (14) ◽  
pp. 1163-1166 ◽  
Author(s):  
Hisao-Ming Wan ◽  
Chien-Chiang Chen ◽  
Te-Sheng Chang ◽  
Raghavan N. Giridhar ◽  
Wen-Teng Wu
Keyword(s):  
Aspergillus Oryzae ◽  
Acid Production ◽  
Kojic Acid ◽  
Strain Improvement ◽  
Induced Mutation ◽  
Kojic Acid Production
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