Chronic Stress Induced by Keeping in Conditions of Nesting Material Deficiency in the Early Postnatal Period Affects Behavior and Stress Reactivity in Male Rats

2022 ◽  
Author(s):  
M. Yu. Stepanichev ◽  
O. A. Nedogreeva ◽  
M. A. Klimanova ◽  
Yu. V. Moiseeva ◽  
M. V. Onufriev ◽  
...  
Keyword(s):  
Chronic Stress ◽  
Stress Reactivity ◽  
Postnatal Period ◽  
Early Postnatal Period ◽  
Male Rats ◽  
Nesting Material

scholarly journals Genistein Exposure During the Early Postnatal Period Favors the Development of Obesity in Female, But Not Male Rats

2013 ◽  
Vol 138 (1) ◽  
pp. 161-174 ◽  
Author(s):  
Rita S. Strakovsky ◽  
Stéphane Lezmi ◽  
Jodi A. Flaws ◽  
Susan L. Schantz ◽  
Yuan-Xiang Pan ◽  
...  
Keyword(s):  
Postnatal Period ◽  
Early Postnatal Period ◽  
Male Rats

EFFECT OF ANDROGENISATION ON ADENOHYPOPHYSIAL PROLACTIN CONTENT IN RATS

1967 ◽  
Vol 54 (4) ◽  
pp. 663-667 ◽  
Author(s):  
M. Kurcz ◽  
K. Kovács ◽  
T. Tiboldi ◽  
A. Orosz
Keyword(s):  
Mammary Gland ◽  
Postnatal Period ◽  
Prolactin Secretion ◽  
Female Rats ◽  
Early Postnatal Period ◽  
Male Rats ◽  
Hormone Production ◽  
Prolactin Content

ABSTRACT The adenohypophyses of androgenised female rats contain significantly less prolactin than control animals. Testosterone phenylpropionate administered in the early postnatal period does not markedly change the adenohypophysial prolactin content of male rats. Since examination of the mammary gland provide no evidence of increased prolactin secretion, the decrease in the adenohypophysial prolactin content of androgenised female rats must be explained by reduced hormone production. It is suggested that androgenisation in female rats influences prolactin production by an action on the hypothalamus.

scholarly journals Stress Modifies the Expression of Glucocorticoid-Responsive Genes by Acting at Epigenetic Levels in the Rat Prefrontal Cortex: Modulatory Activity of Lurasidone

2021 ◽  
Vol 22 (12) ◽  
pp. 6197
Author(s):  
Paola Brivio ◽  
Giulia Sbrini ◽  
Letizia Tarantini ◽  
Chiara Parravicini ◽  
Piotr Gruca ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Chronic Stress ◽  
Chronic Mild Stress ◽  
Male Rats ◽  
Mild Stress ◽  
Experimental Conditions ◽  
Glucocorticoid Responsive Element ◽  
Responsive Element

Epigenetics is one of the mechanisms by which environmental factors can alter brain function and may contribute to central nervous system disorders. Alterations of DNA methylation and miRNA expression can induce long-lasting changes in neurobiological processes. Hence, we investigated the effect of chronic stress, by employing the chronic mild stress (CMS) and the chronic restraint stress protocol, in adult male rats, on the glucocorticoid receptor (GR) function. We focused on DNA methylation specifically in the proximity of the glucocorticoid responsive element (GRE) of the GR responsive genes Gadd45β, Sgk1, and Gilz and on selected miRNA targeting these genes. Moreover, we assessed the role of the antipsychotic lurasidone in modulating these alterations. Chronic stress downregulated Gadd45β and Gilz gene expression and lurasidone normalized the Gadd45β modification. At the epigenetic level, CMS induced hypermethylation of the GRE of Gadd45β gene, an effect prevented by lurasidone treatment. These stress-induced alterations were still present even after a period of rest from stress, indicating the enduring nature of such changes. However, the contribution of miRNA to the alterations in gene expression was moderate in our experimental conditions. Our results demonstrated that chronic stress mainly affects Gadd45β expression and methylation, effects that are prolonged over time, suggesting that stress leads to changes in DNA methylation that last also after the cessation of stress procedure, and that lurasidone is a modifier of such mechanisms.

scholarly journals Changes in pituitary secretion during the early postnatal period and anovulatory syndrome induced by neonatal oestrogen or androgen in rats

Reproduction ◽  
1993 ◽  
Vol 97 (1) ◽  
pp. 13-20 ◽  
Author(s):  
L. Pinilla ◽  
E. Trimino ◽  
P. Garnelo ◽  
C. Bellido ◽  
R. Aguilar ◽  
...  
Keyword(s):  
Postnatal Period ◽  
Early Postnatal Period ◽  
Pituitary Secretion

Changes in masculine sexual behavior, corticosterone and testosterone in response to acute and chronic stress in male rats

2003 ◽  
Vol 44 (4) ◽  
pp. 327-337 ◽  
Author(s):  
S Retana-Márquez ◽  
H Bonilla-Jaime ◽  
G Vázquez-Palacios ◽  
R Martínez-García ◽  
J Velázquez-Moctezuma
Keyword(s):  
Sexual Behavior ◽  
Chronic Stress ◽  
Male Rats ◽  
Acute And Chronic Stress

Fathers’ functional status during pregnancy and the early postnatal period

Midwifery ◽  
2009 ◽  
Vol 25 (6) ◽  
pp. 665-672 ◽  
Author(s):  
Ü. Sevil ◽  
S. Özkan
Keyword(s):  
Functional Status ◽  
Postnatal Period ◽  
Early Postnatal Period

Pharmacological correction of the hepatobiliary system of dry cows as a method of preventing gastrointestinal diseases of calves in the early postnatal period

2021 ◽  
pp. 101-108
Author(s):  
Elena Vasilevna Kuzminova ◽  
Vladimir Anatolevich Grin ◽  
Marina Petrovna Semenenko ◽  
Andrey Georgievich Koshchaev ◽  
Oleg Yurievich Chernykh
Keyword(s):  
Gastrointestinal Diseases ◽  
Postnatal Period ◽  
Early Postnatal Period ◽  
Hepatobiliary System ◽  
Pharmacological Correction
Sign in / Sign up

Export Citation Format

Share Document